PMID- 31759318
OWN - NLM
STAT- MEDLINE
DCOM- 20201231
LR  - 20201231
IS  - 1873-1244 (Electronic)
IS  - 0899-9007 (Linking)
VI  - 70
DP  - 2020 Feb
TI  - Mediterranean diet adherence and congestive heart failure: Relationship with 
      clinical severity and ischemic pathogenesis.
PG  - 110584
LID - S0899-9007(19)30168-6 [pii]
LID - 10.1016/j.nut.2019.110584 [doi]
AB  - OBJECTIVES: To our knowledge, no study has addressed the relationship between 
      adherence to a Mediterranean diet style and severity of heart failure. The aim of 
      this retrospective study was to evaluate the relationship between adherence to 
      the Mediterranean diet assessed using the calculation of Mediterranean diet score 
      and congestive heart failure (CHF), its severity, and pathogenesis. METHODS: We 
      analyzed charts and collected data of all consecutive patients with a diagnosis 
      of CHF at admission to our Internal Medicine Ward from 2008 to 2014. RESULTS: We 
      analyzed 209 patients with CHF and 200 controls. Patients with CHF showed a 
      significantly lower mean MeDi score than controls. At receiver operating 
      characteristic curve analysis, we found a good sensitivity and specificity of 
      mean MeDi score to predict CHF. We also observed a significant positive 
      correlation between MeDi score and ischemic pathogenesis of CHF, a positive 
      relationship between New York Heart Association (NYHA) class and ischemic heart 
      disease, and a significant negative relationship between NYHA class and MeDi 
      score. CONCLUSION: The beneficial effects of adherence to the Mediterranean diet 
      suggest a possible answer to the question of the biochemical bases of our data, 
      which should be seen as the direct consequence of the anti-inflammatory, 
      antioxidant, and anti-remodeling effects linked to the diet.
CI  - Copyright (c) 2019 Elsevier Inc. All rights reserved.
FAU - Tuttolomondo, Antonino
AU  - Tuttolomondo A
AD  - Internal Medicine and Stroke Care Ward, Department of Promoting Health, 
      Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. 
      D'Alessandro, University of Palermo, Palermo, Italy. Electronic address: 
      bruno.tuttolomondo@unipa.it.
FAU - Di Raimondo, Domenico
AU  - Di Raimondo D
AD  - Internal Medicine and Stroke Care Ward, Department of Promoting Health, 
      Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. 
      D'Alessandro, University of Palermo, Palermo, Italy.
FAU - Casuccio, Alessandra
AU  - Casuccio A
AD  - Department of Promoting Health, Maternal-Infant. Excellence and Internal and 
      Specialized Medicine (Promise) G. D'Alessandro, University of Palermo, Palermo, 
      Italy.
FAU - Velardo, Mariachiara
AU  - Velardo M
AD  - Internal Medicine and Stroke Care Ward, Department of Promoting Health, 
      Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. 
      D'Alessandro, University of Palermo, Palermo, Italy.
FAU - Salamone, Giovanni
AU  - Salamone G
AD  - Internal Medicine and Stroke Care Ward, Department of Promoting Health, 
      Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. 
      D'Alessandro, University of Palermo, Palermo, Italy.
FAU - Cataldi, Marco
AU  - Cataldi M
AD  - Internal Medicine and Stroke Care Ward, Department of Promoting Health, 
      Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. 
      D'Alessandro, University of Palermo, Palermo, Italy.
FAU - Corpora, Francesca
AU  - Corpora F
AD  - Internal Medicine and Stroke Care Ward, Department of Promoting Health, 
      Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. 
      D'Alessandro, University of Palermo, Palermo, Italy.
FAU - Restivo, Vincenzo
AU  - Restivo V
AD  - Department of Promoting Health, Maternal-Infant. Excellence and Internal and 
      Specialized Medicine (Promise) G. D'Alessandro, University of Palermo, Palermo, 
      Italy.
FAU - Pecoraro, Rosaria
AU  - Pecoraro R
AD  - IRCCS Centro Neurolesi Bonino Pulejo, Palermo, Italy.
FAU - Della Corte, Vittoriano
AU  - Della Corte V
AD  - Molecular and Clinical Medicine, University of Palermo, Palermo, Italy.
FAU - Maida, Carlo
AU  - Maida C
AD  - Internal Medicine and Stroke Care Ward, Department of Promoting Health, 
      Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. 
      D'Alessandro, University of Palermo, Palermo, Italy.
FAU - Simonetta, Irene
AU  - Simonetta I
AD  - Internal Medicine and Stroke Care Ward, Department of Promoting Health, 
      Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. 
      D'Alessandro, University of Palermo, Palermo, Italy.
FAU - Cirrincione, Anna
AU  - Cirrincione A
AD  - Internal Medicine and Stroke Care Ward, Department of Promoting Health, 
      Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. 
      D'Alessandro, University of Palermo, Palermo, Italy.
FAU - Vassallo, Valerio
AU  - Vassallo V
AD  - Internal Medicine and Stroke Care Ward, Department of Promoting Health, 
      Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. 
      D'Alessandro, University of Palermo, Palermo, Italy.
FAU - Pinto, Antonio
AU  - Pinto A
AD  - Internal Medicine and Stroke Care Ward, Department of Promoting Health, 
      Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. 
      D'Alessandro, University of Palermo, Palermo, Italy.
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20190913
PL  - United States
TA  - Nutrition
JT  - Nutrition (Burbank, Los Angeles County, Calif.)
JID - 8802712
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Diet, Mediterranean/*statistics & numerical data
MH  - Female
MH  - Heart Failure/diet therapy/*pathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Ischemia/etiology/*pathology
MH  - Patient Compliance/*statistics & numerical data
MH  - Retrospective Studies
MH  - *Severity of Illness Index
OTO - NOTNLM
OT  - Adherence
OT  - CAD
OT  - CHF
OT  - Mediterranean diet
OT  - NYHA
EDAT- 2019/11/24 06:00
MHDA- 2021/01/01 06:00
CRDT- 2019/11/24 06:00
PHST- 2018/12/28 00:00 [received]
PHST- 2019/06/24 00:00 [revised]
PHST- 2019/08/27 00:00 [accepted]
PHST- 2019/11/24 06:00 [pubmed]
PHST- 2021/01/01 06:00 [medline]
PHST- 2019/11/24 06:00 [entrez]
AID - S0899-9007(19)30168-6 [pii]
AID - 10.1016/j.nut.2019.110584 [doi]
PST - ppublish
SO  - Nutrition. 2020 Feb;70:110584. doi: 10.1016/j.nut.2019.110584. Epub 2019 Sep 13.