PMID- 31761043
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20191125
LR  - 20191125
IS  - 1873-4324 (Electronic)
IS  - 0003-2670 (Linking)
VI  - 1094
DP  - 2020 Jan 15
TI  - Incorporation of homochiral metal-organic cage into ionic liquid based monolithic 
      column for capillary electrochromatography.
PG  - 160-167
LID - S0003-2670(19)31198-5 [pii]
LID - 10.1016/j.aca.2019.10.002 [doi]
AB  - Metal-organic cages (MOCs) are a novel kind of porous materials which have three 
      dimensional structures with perpetual and well-defined holes. They have attracted 
      wide consideration for relatively simple synthesis and potential applications 
      such as separation, sensing, microreactor and catalysis etc. In this study, a 
      homochiral MOC [Zn(3)L(2)] was prepared as a novel stereoselective stationary 
      phase and added into poly (ionic liquid-co-ethylene dimethacrylate) 
      (Zn(3)L(2)@poly(IL-co-EDMA)) monolith for capillary electrochromatography (CEC). 
      The chiral analytes comprising mandelic acid, benzoin and furoin enantiomer were 
      separated perfectly using the monolithic column Zn(3)L(2)@poly(IL-co-EDMA), and 
      the effects of buffer pH, acetonitrile percentage and buffer concentration on 
      enantiomers separation were confirmed. Moreover, incorporation of MOC [Zn(3)L(2)] 
      into IL polymer monolith strengthened obviously the stereoselective isolation of 
      some positional isomers (such as nitrophenols, nitrotoluenes, xylenes, and 
      ionones). The relative standard deviations (RSDs) of the retention time for 
      intra-day (n = 5) and inter-day (n = 3) and column-to-column (n = 3) 
      enantioseparations were all below 5.0%. This novel monolithic column combined 
      distinct features of the stereoselective materials with the eminent traits of 
      ionic liquid matrix, it has great application potential in CEC.
CI  - Copyright (c) 2019 Elsevier B.V. All rights reserved.
FAU - Li, Zhentao
AU  - Li Z
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of 
      Education, Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, 
      China; State Key Laboratory of Transducer Technology, Chinese Academy of 
      Sciences, Beijing, 10080, China.
FAU - Mao, Zhenkun
AU  - Mao Z
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of 
      Education, Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, 
      China.
FAU - Zhou, Wei
AU  - Zhou W
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of 
      Education, Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, 
      China.
FAU - Chen, Zilin
AU  - Chen Z
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of 
      Education, Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, 
      China; State Key Laboratory of Transducer Technology, Chinese Academy of 
      Sciences, Beijing, 10080, China. Electronic address: chenzl@whu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20191009
PL  - Netherlands
TA  - Anal Chim Acta
JT  - Analytica chimica acta
JID - 0370534
SB  - IM
OTO - NOTNLM
OT  - Electrochromatography
OT  - Enantioseparation
OT  - Ionic liquid polymer
OT  - Metal-organic cages
OT  - Monolithic column
EDAT- 2019/11/26 06:00
MHDA- 2019/11/26 06:01
CRDT- 2019/11/26 06:00
PHST- 2019/08/10 00:00 [received]
PHST- 2019/10/01 00:00 [revised]
PHST- 2019/10/06 00:00 [accepted]
PHST- 2019/11/26 06:00 [entrez]
PHST- 2019/11/26 06:00 [pubmed]
PHST- 2019/11/26 06:01 [medline]
AID - S0003-2670(19)31198-5 [pii]
AID - 10.1016/j.aca.2019.10.002 [doi]
PST - ppublish
SO  - Anal Chim Acta. 2020 Jan 15;1094:160-167. doi: 10.1016/j.aca.2019.10.002. Epub 
      2019 Oct 9.