PMID- 31762240
OWN - NLM
STAT- MEDLINE
DCOM- 20191202
LR  - 20200108
IS  - 1672-173X (Print)
IS  - 1672-173X (Linking)
VI  - 50
IP  - 5
DP  - 2019 Sep
TI  - [Cardiac Magnetic Resonance Imaging Study of Ventricular Myocardial Deformation 
      in Spontaneous T2DM Rhesus Monkey].
PG  - 695-700
AB  - OBJECTIVE: To assess biventricular, especially right ventricular, function and 
      deformationin rhesus monkeys with spontaneous type 2 diabetes mellitus (T2DM) 
      using cardiac magnetic resonance (CMR). METHODS: Twelve male spontaneous T2DM 
      rhesus monkeys and age, sex, body mass matched 9 healthy rhesus monkeys without 
      hypertension and myocardial infarction were included in this study. Fasting blood 
      glucose (FPG), glycated hemoglobin (HbA1c) and blood liquid levels were measured. 
      Biventricular function and myocardial deformations were evaluated by CMR cine and 
      tissue-tracking. RESULTS: Compared with control, the FPG and HbA1c levers were 
      significantly increased in T2DM group, but there was no significant difference in 
      body mass and age between the two groups. CMR result showed that there was no 
      significant decrease in right ventricle and left ventricle ejection fraction in 
      T2DM (P < 0.05). However, the absolute value of radial and circumferential global 
      peak systolic strain, systolic strain rate and three directions global peak 
      diastolic strain rate of the right ventricle free wall were lower in the T2DM 
      group (P < 0.05). Also, only radial and circumferential peak systolic strain and 
      radial diastolic strain rate of left ventricle were higher (P < 0.05). 
      CONCLUSIONS: Right ventricle showed systolic and diastolic dysfunction which were 
      consistent with left ventricle in T2DM by CMR-tissue tracking.
CI  - Copyright(c) by Editorial Board of Journal of Sichuan University (Medical Science 
      Edition).
FAU - Zhu, Tong
AU  - Zhu T
AD  - Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, 
      China.
FAU - Zeng, Wen
AU  - Zeng W
AD  - Sichuan Primed Shines Bio-tech Co., Ltd, Chengdu 610041, China.
FAU - Chen, Yu-Shu
AU  - Chen YS
AD  - Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, 
      China.
FAU - Zhang, Yu
AU  - Zhang Y
AD  - Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, 
      China.
FAU - Sun, Jia-Yu
AU  - Sun JY
AD  - Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, 
      China.
FAU - Cheng, Wei
AU  - Cheng W
AD  - Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, 
      China.
FAU - Wang, Lei
AU  - Wang L
AD  - Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, 
      China.
FAU - Gong, Li
AU  - Gong L
AD  - Sichuan Primed Shines Bio-tech Co., Ltd, Chengdu 610041, China.
FAU - Gao, Fa-Bao
AU  - Gao FB
AD  - Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, 
      China.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Sichuan Da Xue Xue Bao Yi Xue Ban
JT  - Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical 
      science edition
JID - 101162609
SB  - IM
MH  - Animals
MH  - Diabetes Mellitus, Type 2/*complications
MH  - Heart Ventricles/*diagnostic imaging
MH  - Macaca mulatta
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Reproducibility of Results
MH  - Stroke Volume
MH  - *Ventricular Dysfunction, Right
OTO - NOTNLM
OT  - CMR tissue tracking
OT  - Rhesus monkey
OT  - T2DM
EDAT- 2019/11/26 06:00
MHDA- 2019/12/04 06:00
CRDT- 2019/11/26 06:00
PHST- 2019/11/26 06:00 [entrez]
PHST- 2019/11/26 06:00 [pubmed]
PHST- 2019/12/04 06:00 [medline]
PST - ppublish
SO  - Sichuan Da Xue Xue Bao Yi Xue Ban. 2019 Sep;50(5):695-700.