PMID- 31762390
OWN - NLM
STAT- MEDLINE
DCOM- 20200914
LR  - 20200914
IS  - 1502-4725 (Electronic)
IS  - 0803-9488 (Linking)
VI  - 74
IP  - 4
DP  - 2020 May
TI  - Negative symptom configuration in first episode Schizophrenia: findings from the 
      "Parma Early Psychosis" program.
PG  - 251-258
LID - 10.1080/08039488.2019.1695286 [doi]
AB  - Purpose: Identifying distinct dimensions of negative symptoms in First Episode 
      Schizophrenia (FES) might result in a better understanding and treatment of this 
      invalidating symptomatology. Aim of this study was to examine negative symptom 
      structure in FES patients using the Positive and Negative Syndrome Scale 
      (PANSS).Materials and Methods: All 147 participants, aged 12-35 years, completed 
      the PANSS and the Global Assessment of Functioning (GAF) scale. A principal 
      component analysis with varimax rotation was performed to investigate PANSS 
      negative symptom structure in the FES total sample.Results: A 2-factor model 
      (i.e. "Expressive Deficits" and "Asociality" dimensions) was identified. Only 
      "Expressive Deficits" domain had a significant negative correlation with baseline 
      GAF score.Conclusions: This bipartite solution seems to be adequate to describe 
      the phenomenological variety of negative symptoms experienced by FES individuals 
      at the point of entry in early intervention services.
FAU - Pelizza, Lorenzo
AU  - Pelizza L
AUID- ORCID: 0000-0003-4746-2061
AD  - Department of Mental Health and Pathological Addiction, Azienda USL di Parma, 
      Parma, Italy.
FAU - Landi, Giulia
AU  - Landi G
AD  - Department of Mental Health and Pathological Addiction, Azienda USL di Parma, 
      Parma, Italy.
FAU - Pellegrini, Clara
AU  - Pellegrini C
AD  - Psychiatric Unit, Department of Medicine and Surgery, Universita di Parma, Parma, 
      Italy.
FAU - Quattrone, Emanuela
AU  - Quattrone E
AD  - Department of Mental Health and Pathological Addiction, Azienda USL di Parma, 
      Parma, Italy.
FAU - Azzali, Silvia
AU  - Azzali S
AD  - Department of Mental Health and Pathological Addiction, Azienda USL-IRCCS di 
      Reggio Emilia, Reggio Emilia, Italy.
FAU - Pellegrini, Pietro
AU  - Pellegrini P
AD  - Department of Mental Health and Pathological Addiction, Azienda USL di Parma, 
      Parma, Italy.
FAU - Leuci, Emanuela
AU  - Leuci E
AD  - Department of Mental Health and Pathological Addiction, Azienda USL di Parma, 
      Parma, Italy.
LA  - eng
PT  - Journal Article
PT  - Pragmatic Clinical Trial
DEP - 20191125
PL  - England
TA  - Nord J Psychiatry
JT  - Nordic journal of psychiatry
JID - 100927567
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Child
MH  - Early Diagnosis
MH  - Female
MH  - Humans
MH  - Italy/epidemiology
MH  - Male
MH  - Principal Component Analysis/methods
MH  - *Psychiatric Status Rating Scales
MH  - Psychotic Disorders/diagnosis/epidemiology/psychology
MH  - Schizophrenia/*diagnosis/*epidemiology
MH  - *Schizophrenic Psychology
MH  - Young Adult
OTO - NOTNLM
OT  - Negative symptoms
OT  - dimensions
OT  - early psychosis
OT  - factor analysis
OT  - first episode schizophrenia
EDAT- 2019/11/26 06:00
MHDA- 2020/09/15 06:00
CRDT- 2019/11/26 06:00
PHST- 2019/11/26 06:00 [pubmed]
PHST- 2020/09/15 06:00 [medline]
PHST- 2019/11/26 06:00 [entrez]
AID - 10.1080/08039488.2019.1695286 [doi]
PST - ppublish
SO  - Nord J Psychiatry. 2020 May;74(4):251-258. doi: 10.1080/08039488.2019.1695286. 
      Epub 2019 Nov 25.