PMID- 31765843
OWN - NLM
STAT- MEDLINE
DCOM- 20210618
LR  - 20210618
IS  - 1873-2763 (Electronic)
IS  - 1873-2763 (Linking)
VI  - 131
DP  - 2020 Feb
TI  - Bone density status in a large population of patients with anorexia nervosa.
PG  - 115161
LID - S8756-3282(19)30455-7 [pii]
LID - 10.1016/j.bone.2019.115161 [doi]
AB  - Anorexia nervosa (AN) is associated with multiple medical complications. One of 
      the rare permanent complications of AN is the deleterious effect that it has on a 
      patient's bone mineral density (BMD). We report on the Dual-Energy X-ray 
      Absorptiometry (DXA) findings of 336 consecutive patients with AN. Also, we 
      investigated the effects of different factors on these DXA results. These factors 
      included age, body mass index (BMI), percentage of ideal body weight (IBW), 
      duration of illness, duration of amenorrhea, medications such as proton pump 
      inhibitors (PPI) or selective serotonin reuptake inhibitors (SSRI), tobacco use 
      and 25-hydroxy vitamin D levels. This study demonstrated a concerning high 
      prevalence of reduced bone mineral density in patients with AN. Thus, the 
      implication being that those involved in the care of patients with AN need to be 
      cognizant of this serious complication and not be assuaged by the young age of 
      this patient population.
CI  - Copyright (c) 2019 Elsevier Inc. All rights reserved.
FAU - Workman, Cassandra
AU  - Workman C
AD  - Eating Recovery Center, Denver, CO, United States of America.
FAU - Blalock, Dan V
AU  - Blalock DV
AD  - Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), 
      Durham Veterans Affairs Medical Center, Durham, NC, United States of America; 
      Department of Psychiatry and Behavioral Sciences, Duke University School of 
      Medicine, Durham, NC, United States of America.
FAU - Mehler, Philip S
AU  - Mehler PS
AD  - Eating Recovery Center, Denver, CO, United States of America; Departments of 
      Medicine, Denver Health and University of Colorado Health Science Center, Aurora, 
      CO, United States of America. Electronic address: Phil.mehler@eatingrecovery.com.
LA  - eng
PT  - Journal Article
DEP - 20191123
PL  - United States
TA  - Bone
JT  - Bone
JID - 8504048
SB  - IM
MH  - Absorptiometry, Photon
MH  - Amenorrhea/epidemiology
MH  - *Anorexia Nervosa/epidemiology
MH  - Body Mass Index
MH  - *Bone Density
MH  - Female
MH  - Humans
OTO - NOTNLM
OT  - Anorexia nervosa
OT  - Dual-energy x-ray absorptiometry
OT  - Osteopenia
OT  - Osteoporosis
EDAT- 2019/11/26 06:00
MHDA- 2021/06/22 06:00
CRDT- 2019/11/26 06:00
PHST- 2019/08/19 00:00 [received]
PHST- 2019/10/29 00:00 [revised]
PHST- 2019/11/20 00:00 [accepted]
PHST- 2019/11/26 06:00 [pubmed]
PHST- 2021/06/22 06:00 [medline]
PHST- 2019/11/26 06:00 [entrez]
AID - S8756-3282(19)30455-7 [pii]
AID - 10.1016/j.bone.2019.115161 [doi]
PST - ppublish
SO  - Bone. 2020 Feb;131:115161. doi: 10.1016/j.bone.2019.115161. Epub 2019 Nov 23.