PMID- 31768338
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220411
IS  - 2235-0640 (Print)
IS  - 2235-0802 (Electronic)
IS  - 2235-0640 (Linking)
VI  - 8
IP  - 5
DP  - 2019 Oct
TI  - Moderate Frequency of Anti-Thyroglobulin Antibodies in the Early Phase of 
      Subacute Thyroiditis.
PG  - 268-272
LID - 10.1159/000501033 [doi]
AB  - BACKGROUND: Subacute thyroiditis is generally believed to be induced by viral 
      infection, and little attention has been paid to anti-thyroid antibodies. 
      OBJECTIVES: Our study aimed to assess the prevalence of anti-thyroid antibodies 
      in patients with subacute thyroiditis. METHODS: Anti-thyroglobulin (TgAb) and 
      anti-thyroid peroxidase antibodies (TPOAb) were measured with 4 different 
      immunoassay kits currently used in 40 patients in the early phase of subacute 
      thyroiditis. RESULTS: The proportion of samples positive for TgAb was 52.5 +/- 
      13.7% (mean of 4 kits), which was significantly (p < 0.05) higher than that 
      positive for TPOAb (15.6 +/- 6.5%). The prevalence of positive TgAb alone (negative 
      TPOAb) was also significantly higher than that of TPOAb alone (negative TgAb). 
      TgAb titers decreased or disappeared within 4 months to 6 years in 6 patients. 
      CONCLUSIONS: Patient samples were moderately positive for TgAb initially, but the 
      titer decreased or disappeared afterwards in subacute thyroiditis.
CI  - Copyright (c) 2019 by S. Karger AG, Basel.
FAU - Nishihara, Eijun
AU  - Nishihara E
AD  - Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan.
FAU - Amino, Nobuyuki
AU  - Amino N
AD  - Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan.
FAU - Kudo, Takumi
AU  - Kudo T
AD  - Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan.
FAU - Kohsaka, Kazuyoshi
AU  - Kohsaka K
AD  - Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan.
FAU - Ito, Mitsuru
AU  - Ito M
AD  - Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan.
FAU - Fukata, Shuji
AU  - Fukata S
AD  - Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan.
FAU - Nishikawa, Mitsushige
AU  - Nishikawa M
AD  - Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan.
FAU - Nakamura, Hirotoshi
AU  - Nakamura H
AD  - Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan.
FAU - Miyauchi, Akira
AU  - Miyauchi A
AD  - Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan.
LA  - eng
PT  - Journal Article
DEP - 20190715
PL  - England
TA  - Eur Thyroid J
JT  - European thyroid journal
JID - 101604579
PMC - PMC6873036
OTO - NOTNLM
OT  - Anti-TPO antibodies
OT  - Anti-thyroglobulin antibodies
OT  - Autoimmune thyroiditis
OT  - Subacute thyroiditis
COIS- None of the authors has any potential conflict of interest associated with this 
      research.
EDAT- 2019/11/27 06:00
MHDA- 2019/11/27 06:01
PMCR- 2020/04/01
CRDT- 2019/11/27 06:00
PHST- 2019/03/15 00:00 [received]
PHST- 2019/05/17 00:00 [revised]
PHST- 2019/11/27 06:00 [entrez]
PHST- 2019/11/27 06:00 [pubmed]
PHST- 2019/11/27 06:01 [medline]
PHST- 2020/04/01 00:00 [pmc-release]
AID - etj-0008-0268 [pii]
AID - 10.1159/000501033 [doi]
PST - ppublish
SO  - Eur Thyroid J. 2019 Oct;8(5):268-272. doi: 10.1159/000501033. Epub 2019 Jul 15.