PMID- 31769843 OWN - NLM STAT- MEDLINE DCOM- 20200717 LR - 20200717 IS - 1753-4887 (Electronic) IS - 0029-6643 (Linking) VI - 78 IP - 5 DP - 2020 May 1 TI - Impact of interventions to reduce overnutrition on healthcare costs related to obesity and type 2 diabetes: a systematic review. PG - 412-435 LID - 10.1093/nutrit/nuz070 [doi] AB - CONTEXT: In recent decades, obesity and type 2 diabetes mellitus (T2DM) have both become global epidemics associated with substantial healthcare needs and costs. OBJECTIVE: The aim of this review was to critically assess nutritional interventions for their impact on healthcare costs to community-dwelling individuals regarding T2DM or obesity or both, specifically using CHEERS (Consolidated Health Economic Evaluation Reporting Standards) criteria to assess the economic components of the evidence. DATA SOURCES: Searches were executed in Embase, EconLit, AgEcon, PubMed, and Web of Science databases. STUDY SELECTION: Studies were included if they had a nutritional perspective, reported an economic evaluation that included healthcare costs, and focused on obesity or T2DM or both. Studies were excluded if they examined clinical nutritional preparations, dietary supplements, industrially modified dietary components, micronutrient deficiencies, or undernutrition; if they did not report the isolated impact of nutrition in complex or lifestyle interventions; or if they were conducted in animals or attempted to transfer findings from animals to humans. DATA EXTRACTION: A systematic review was performed according to PRISMA guidelines. Using predefined search terms, 21 studies evaluating food habit interventions or taxation of unhealthy foods and beverages were extracted and evaluated using CHEERS criteria. RESULTS: Overall, these studies showed that nutrition interventions and taxation approaches could lead to cost savings and improved health outcomes when compared with current practice. All of the included studies used external sources and economic modeling or risk estimations with population-attributable risks to calculate economic outcomes. CONCLUSIONS: Most evidence supported taxation approaches. The effect of nutritional interventions has not been adequately assessed. Controlled studies to directly measure economic impacts are warranted. CI - (c) The Author(s) 2019. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. FAU - Olm, Michaela AU - Olm M AD - Institute for Medical Information Processing, Biometry, and Epidemiology, Ludwig-Maximilians University Munich, Munich, Bavaria, Germany. AD - Institute of Health Economics and Health Care Management, Helmholtz Zentrum Munchen, Neuherberg, Germany. AD - Institute of General Practice and Health Services Research, University Hospital rechts der Isar, Technical University of Munich, Munich, Germany. FAU - Stark, Renee G AU - Stark RG AD - Institute of Health Economics and Health Care Management, Helmholtz Zentrum Munchen, Neuherberg, Germany. FAU - Beck, Nathanael AU - Beck N AD - Munich Center of Health Sciences, Ludwig-Maximilians University Munich, Munich, Bavaria, Germany. FAU - Roger, Christina AU - Roger C AD - Competence Center for Nutrition and the Institute of the Bavarian State Ministry of Food, Agriculture and Forestry, Freising, Bavaria, Germany. FAU - Leidl, Reiner AU - Leidl R AD - Institute of Health Economics and Health Care Management, Helmholtz Zentrum Munchen, Neuherberg, Germany. AD - Munich Center of Health Sciences, Ludwig-Maximilians University Munich, Munich, Bavaria, Germany. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Systematic Review PL - United States TA - Nutr Rev JT - Nutrition reviews JID - 0376405 SB - IM MH - Diabetes Mellitus, Type 2/*diet therapy/*economics MH - *Health Care Costs MH - Humans MH - Obesity/*diet therapy/*economics MH - Taxes OTO - NOTNLM OT - healthcare costs OT - nutrition OT - obesity OT - taxation OT - type 2 diabetes mellitus EDAT- 2019/11/27 06:00 MHDA- 2020/07/18 06:00 CRDT- 2019/11/27 06:00 PHST- 2019/11/27 06:00 [pubmed] PHST- 2020/07/18 06:00 [medline] PHST- 2019/11/27 06:00 [entrez] AID - 5643891 [pii] AID - 10.1093/nutrit/nuz070 [doi] PST - ppublish SO - Nutr Rev. 2020 May 1;78(5):412-435. doi: 10.1093/nutrit/nuz070.