PMID- 31770282
OWN - NLM
STAT- MEDLINE
DCOM- 20191206
LR  - 20221005
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 98
IP  - 48
DP  - 2019 Nov
TI  - Comparison of outcomes between type 2 diabetic and non-diabetic incident 
      hemodialysis patients with functioning arteriovenous fistulas.
PG  - e18216
LID - 10.1097/MD.0000000000018216 [doi]
LID - e18216
AB  - This study compared clinical outcomes of patient survival and arteriovenous 
      fistula (AVF) patency between incident hemodialysis patients with and without 
      type 2 diabetes mellitus (T2DM).Between January 2011 and December 2013, 384 
      consecutive incident hemodialysis patients with confirmed first upper-extremity 
      AVF placement were divided into a T2DM group (n = 180, 46.9%) and a non-DM group 
      (n = 204, 53.1%) and analyzed retrospectively. The primary outcome was all-cause 
      mortality, and secondary outcome was AVF patency.Patients in the T2DM group had a 
      higher prevalence of hypertension (P = .02), smoking (P < .01), cardiovascular 
      disease (P < .01), history of cerebrovascular accident (CVA) (P < .01), and 
      peripheral arterial occlusive disease (P < .01) than those in the non-DM group. 
      On Kaplan-Meier survival analysis, the overall survival and AVF patency rates 
      were significantly higher in the non-DM group relative to the T2DM group (both 
      P < .01). In the adjusted model, older age (hazard ratio [HR], 1.04; 95% 
      confidence interval [CI], 1.02-1.06; P < .01), T2DM (HR, 1.76; 95% CI, 1.12-2.77; 
      P = .014), and history of CVA (HR, 1.76; 95% CI, 1.04-2.98; P = .04) were 
      significantly associated with an increased risk of mortality. Older age and T2DM 
      were independently associated with decreased primary (HR, 1.03; 95% CI, 
      1.02-1.04; P < .01, HR, 1.69; 95% CI, 1.22-2.33; P < .01, respectively) and 
      secondary (HR, 1.03; 95% CI, 1.01-1.04; P < .01, HR, 2.07; 95% CI, 1.42-3.00; 
      P < .01, respectively) AVF patency during follow-up.Compared with patients in the 
      non-DM group, patients in the T2DM group had a higher mortality rate and worse 
      AVF patency rates.
FAU - Jeong, Seonjeong
AU  - Jeong S
AD  - Department of Surgery.
FAU - Kwon, Hyunwook
AU  - Kwon H
AD  - Department of Surgery.
FAU - Chang, Jai Won
AU  - Chang JW
AD  - Department of Internal Medicine.
FAU - Kim, Min-Ju
AU  - Kim MJ
AD  - Department of Clinical Epidemiology and Biostatistics, University of Ulsan 
      College of Medicine and Asan Medical Center, Seoul, Republic of Korea.
FAU - Ganbold, Khaliun
AU  - Ganbold K
AD  - Department of Surgery, Mongolian National University of Medical Sciences, 
      Ulaanbaatar, Mongolia.
FAU - Han, Youngjin
AU  - Han Y
AD  - Department of Surgery.
FAU - Kwon, Tae-Won
AU  - Kwon TW
AD  - Department of Surgery.
FAU - Cho, Yong-Pil
AU  - Cho YP
AD  - Department of Surgery.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - *Arteriovenous Shunt, Surgical/adverse effects/methods
MH  - Comorbidity
MH  - *Diabetes Mellitus, Type 2/diagnosis/epidemiology
MH  - Female
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - *Kidney Failure, Chronic/epidemiology/therapy
MH  - Male
MH  - Middle Aged
MH  - Outcome and Process Assessment, Health Care
MH  - *Renal Dialysis/adverse effects/methods/mortality
MH  - Retrospective Studies
MH  - Risk Assessment
MH  - Vascular Patency
PMC - PMC6890339
COIS- The authors have no funding and conflicts of interests to disclose.
EDAT- 2019/11/27 06:00
MHDA- 2019/12/18 06:00
PMCR- 2019/11/27
CRDT- 2019/11/27 06:00
PHST- 2019/11/27 06:00 [entrez]
PHST- 2019/11/27 06:00 [pubmed]
PHST- 2019/12/18 06:00 [medline]
PHST- 2019/11/27 00:00 [pmc-release]
AID - 00005792-201911290-00091 [pii]
AID - MD-D-19-05720 [pii]
AID - 10.1097/MD.0000000000018216 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2019 Nov;98(48):e18216. doi: 10.1097/MD.0000000000018216.