PMID- 31780613
OWN - NLM
STAT- MEDLINE
DCOM- 20200427
LR  - 20211129
IS  - 1757-790X (Electronic)
IS  - 1757-790X (Linking)
VI  - 12
IP  - 11
DP  - 2019 Nov 28
TI  - Subacute cutaneous lupus erythematosus with a possible paraneoplastic association 
      with melanoma.
LID - 10.1136/bcr-2019-230558 [doi]
LID - e230558
AB  - A 52-year-old man was referred to our dermatology clinic for a diagnosis of 
      melanoma. At the time, his melanoma was excised he developed an annular, 
      polycyclic, scaling eruption consistent with subacute cutaneous lupus 
      erythematosus (SCLE). Skin biopsy and laboratory evaluation confirmed this 
      diagnosis. The patient had been using pantoprazole for gastro-oesophageal reflux 
      disease for the last 3 years. The patient's melanoma was treated surgically, and 
      his SCLE was treated with topical steroids and hydroxychloroquine. His SCLE 
      cleared rapidly, his steroids and hydroxychloroquine were stopped and he remains 
      free of SCLE off of treatment. The parallel course of the patient's SCLE and 
      melanoma prompted consideration of SCLE as paraneoplastic to melanoma in this 
      case. The clinical picture was complicated by the patient's use of a proton pump 
      inhibitor, which are common causes of drug-induced SCLE. To our knowledge, this 
      is the first reported case of possible paraneoplastic SCLE associated with 
      melanoma.
CI  - (c) BMJ Publishing Group Limited 2019. No commercial re-use. See rights and 
      permissions. Published by BMJ.
FAU - Hirner, Jesse
AU  - Hirner J
AD  - Dermatology, University of Missouri, Columbia, Missouri, USA jphirner@gmail.com.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20191128
PL  - England
TA  - BMJ Case Rep
JT  - BMJ case reports
JID - 101526291
SB  - IM
MH  - Humans
MH  - Lupus Erythematosus, Cutaneous/*diagnosis
MH  - Male
MH  - Melanoma/*diagnosis
MH  - Middle Aged
MH  - Paraneoplastic Syndromes/*diagnosis
MH  - Skin Neoplasms/*diagnosis
PMC - PMC6887353
OTO - NOTNLM
OT  - dermatology
OT  - drugs and medicines
OT  - oncology
OT  - rheumatology
COIS- Competing interests: None declared.
EDAT- 2019/11/30 06:00
MHDA- 2020/04/28 06:00
PMCR- 2021/11/28
CRDT- 2019/11/30 06:00
PHST- 2019/11/30 06:00 [entrez]
PHST- 2019/11/30 06:00 [pubmed]
PHST- 2020/04/28 06:00 [medline]
PHST- 2021/11/28 00:00 [pmc-release]
AID - 12/11/e230558 [pii]
AID - bcr-2019-230558 [pii]
AID - 10.1136/bcr-2019-230558 [doi]
PST - epublish
SO  - BMJ Case Rep. 2019 Nov 28;12(11):e230558. doi: 10.1136/bcr-2019-230558.