PMID- 31781303 OWN - NLM STAT- MEDLINE DCOM- 20200427 LR - 20200427 IS - 1875-8630 (Electronic) IS - 0278-0240 (Print) IS - 0278-0240 (Linking) VI - 2019 DP - 2019 TI - Investigation of Acoustic Cardiographic Parameters before and after Hemodialysis. PG - 5270159 LID - 10.1155/2019/5270159 [doi] LID - 5270159 AB - Patients with end-stage renal disease are at an increased risk of cardiovascular diseases and associated mortality. Acoustic cardiography is a technique in which cardiac acoustic data is synchronized with electric information to detect and characterize heart sounds and detect heart failure early. The aim of this study was to investigate acoustic cardiographic parameters before and after hemodialysis (HD) and their correlations with ankle-brachial index (ABI), brachial-ankle pulse wave velocity (baPWV), and ratio of brachial preejection period to ejection time (bPEP/bET) obtained from an ABI-form device in HD patients. This study enrolled 162 HD patients between October 2016 and April 2018. Demographic, medical, and laboratory data were collected. Acoustic cardiography was performed before and after HD to assess parameters including third heart sound (S3), fourth heart sound (S4), systolic dysfunction index (SDI), electromechanical activation time (EMAT), and left ventricular systolic time (LVST). The mean age of the enrolled patients was 60.4 +/- 10.9 years, and 86 (53.1%) patients were male. S4 (p < 0.001) and LVST (p < 0.001) significantly decreased after HD, but EMAT (p < 0.001) increased. Multivariate forward linear regression analysis showed that EMAT/LVST before HD was negatively associated with albumin (unstandardized coefficient beta = -0.076; p = 0.004) and ABI (unstandardized coefficient beta = -0.115; p = 0.011) and positively associated with bPEP/bET (unstandardized coefficient beta = 0.278; p = 0.003). Screening HD patients with acoustic cardiography may help to identify patients at a high risk of malnutrition, peripheral artery disease, and left ventricular systolic dysfunction. CI - Copyright (c) 2019 Hui-Ju Tsai et al. FAU - Tsai, Hui-Ju AU - Tsai HJ AUID- ORCID: 0000-0001-9285-772X AD - Department of Family Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. AD - Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. FAU - Tsai, Yi-Chun AU - Tsai YC AD - Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. AD - Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. FAU - Huang, Jiun-Chi AU - Huang JC AUID- ORCID: 0000-0002-5897-2860 AD - Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. AD - Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. AD - Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. FAU - Wu, Pei-Yu AU - Wu PY AUID- ORCID: 0000-0003-4499-6631 AD - Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. AD - Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. AD - Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. FAU - Chen, Szu-Chia AU - Chen SC AUID- ORCID: 0000-0002-1610-4184 AD - Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. AD - Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. AD - Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. FAU - Chiu, Yi-Wen AU - Chiu YW AD - Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. AD - Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. FAU - Chang, Jer-Ming AU - Chang JM AUID- ORCID: 0000-0003-0071-1710 AD - Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. AD - Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. FAU - Chen, Hung-Chun AU - Chen HC AD - Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. AD - Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. LA - eng PT - Journal Article DEP - 20191105 PL - United States TA - Dis Markers JT - Disease markers JID - 8604127 SB - IM MH - Acoustics MH - Ankle Brachial Index/*statistics & numerical data MH - Brachial Artery/*physiopathology MH - Case-Control Studies MH - Electrocardiography/*methods MH - Female MH - Follow-Up Studies MH - Heart Failure/*diagnosis/etiology MH - Humans MH - Kidney Failure, Chronic/therapy MH - Male MH - Middle Aged MH - Predictive Value of Tests MH - Pulse Wave Analysis/*statistics & numerical data MH - Renal Dialysis/*adverse effects MH - Risk Assessment/*methods MH - *Stroke Volume PMC - PMC6874870 COIS- All authors declare that they have no conflict of interests to state. EDAT- 2019/11/30 06:00 MHDA- 2020/04/28 06:00 PMCR- 2019/11/05 CRDT- 2019/11/30 06:00 PHST- 2019/07/01 00:00 [received] PHST- 2019/10/22 00:00 [accepted] PHST- 2019/11/30 06:00 [entrez] PHST- 2019/11/30 06:00 [pubmed] PHST- 2020/04/28 06:00 [medline] PHST- 2019/11/05 00:00 [pmc-release] AID - 10.1155/2019/5270159 [doi] PST - epublish SO - Dis Markers. 2019 Nov 5;2019:5270159. doi: 10.1155/2019/5270159. eCollection 2019.