PMID- 31781434 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 2090-6625 (Print) IS - 2090-6633 (Electronic) VI - 2019 DP - 2019 TI - Complicated Urinary Tract Tuberculosis in a 13-Year-Old Adolescent with Chronic Kidney Disease and Antituberculous Drug-Induced Hepatotoxicity. PG - 7370150 LID - 10.1155/2019/7370150 [doi] LID - 7370150 AB - Urinary tract tuberculosis (TB) is a rare extrapulmonary manifestation of TB in children. The disease is potentially underdiagnosed because it clinically resembles other urinary tract infections. A 13-year-old adolescent girl presented with pain, difficulty in micturition, and gross hematuria for almost two years before admission, and she had left flank pain since one year ago and significant loss of body weight during the illness. The close TB contact was her grandmother who was on TB treatment. Acid-fast bacilli yielded positive result, Mantoux test was positive (17 mm), urine GeneXpert MTB/Rif was positive; tuberculoma was identified on kidney histopathology, and a diuretic renogram revealed an uncorrected glomerular filtration rate (GFR) of the right and left kidney to be 32.5 mL/min/1.73 m(2) and 5 mL/min/1.73 m(2), respectively. During the treatment, oral anti-TB drug-induced hepatotoxicity (ADIH) occurred to the patient. This problem was solved with management according to the British Thoracic Society (BTS) guidelines. Screening TB in children is very important for a better outcome. If children complain of some complicated urinary tract infection, TB should be suspected. Optimaly treating children with urinary tract TB exagerrated with ADIH and CKD is very challenging. CI - Copyright (c) 2019 Heda Melinda Nataprawira et al. FAU - Nataprawira, Heda Melinda AU - Nataprawira HM AUID- ORCID: 0000-0001-8079-6544 AD - Respirology Division, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Pasteur 38, Bandung, West Java 40161, Indonesia. FAU - Pratama, Adhitya Agung AU - Pratama AA AD - Nephrology Division, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Pasteur 38, Bandung, West Java 40161, Indonesia. FAU - Widiasta, Ahmedz AU - Widiasta A AUID- ORCID: 0000-0001-5664-089X AD - Nephrology Division, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Pasteur 38, Bandung, West Java 40161, Indonesia. FAU - Sibarani, Jupiter AU - Sibarani J AD - Urology Department, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Pasteur 38, Bandung, West Java 40161, Indonesia. FAU - Hilmanto, Dany AU - Hilmanto D AD - Nephrology Division, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Pasteur 38, Bandung, West Java 40161, Indonesia. FAU - Sekarwana, Nanan AU - Sekarwana N AD - Nephrology Division, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Pasteur 38, Bandung, West Java 40161, Indonesia. FAU - Rachmadi, Dedi AU - Rachmadi D AD - Nephrology Division, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Pasteur 38, Bandung, West Java 40161, Indonesia. LA - eng PT - Case Reports DEP - 20191023 PL - Egypt TA - Case Rep Infect Dis JT - Case reports in infectious diseases JID - 101573243 PMC - PMC6855035 COIS- The authors declare that there are no financial and personal relationships with other people or organizations that could inappropriately influence their work. EDAT- 2019/11/30 06:00 MHDA- 2019/11/30 06:01 PMCR- 2019/10/23 CRDT- 2019/11/30 06:00 PHST- 2019/01/24 00:00 [received] PHST- 2019/08/29 00:00 [accepted] PHST- 2019/11/30 06:00 [entrez] PHST- 2019/11/30 06:00 [pubmed] PHST- 2019/11/30 06:01 [medline] PHST- 2019/10/23 00:00 [pmc-release] AID - 10.1155/2019/7370150 [doi] PST - epublish SO - Case Rep Infect Dis. 2019 Oct 23;2019:7370150. doi: 10.1155/2019/7370150. eCollection 2019.