PMID- 31781520
OWN - NLM
STAT- MEDLINE
DCOM- 20200529
LR  - 20200529
IS  - 2291-2797 (Electronic)
IS  - 2291-2789 (Print)
IS  - 2291-2789 (Linking)
VI  - 2019
DP  - 2019
TI  - The Impact of Revascularisation on Quality of Life in Chronic Mesenteric 
      Ischemia.
PG  - 7346013
LID - 10.1155/2019/7346013 [doi]
LID - 7346013
AB  - BACKGROUND: Chronic mesenteric ischemia (CMI) is characterized by long-standing 
      abdominal symptoms due to insufficient mesenteric circulation. Data on the effect 
      of revascularisation on quality of life (QoL) for CMI are scarce. This study is 
      the first to evaluate the impact of revascularisation on quality of life. 
      METHODS: Seventy-nine patients with CMI or acute-on-chronic mesenteric ischemia 
      (AoCMI) underwent an intervention of one or more mesenteric arteries between 
      January 2010 and July 2012. QoL before and after intervention was measured with 
      the EuroQol-5D. Preintervention questionnaires were of standard care. 
      Postintervention data were obtained by resending a questionnaire to the patients 
      between February and May 2013. To investigate the clinical relevance of our 
      findings, the minimal clinically important difference (MCID) was used. Since 
      there is no established MCID for CMI, we used the literature reference MCID of 
      inflammatory bowel syndrome (IBS) of 0.074. RESULTS: Fifty-five (69.6%) of 79 
      patients returned their questionnaire and 23 (29.1%) were completely filled out. 
      There was a significant increase of the median EQ-index score from 0.70 to 0.81 
      (p=0.02) and a significant reduction of symptoms in the domains usual activities 
      (34.4%) and pain/discomfort (32.3%). There was a significant improvement of 17% 
      in overall current health condition (VAS) (p=0.001). The MCID between baseline 
      and postoperative EQ-5D index score was 0.162, indicating a clinically relevant 
      improvement of quality of life after revascularisation. CONCLUSION: Quality of 
      life of CMI patients is improved after mesenteric artery revascularisation.
CI  - Copyright (c) 2019 J. T. M. Blauw et al.
FAU - Blauw, J T M
AU  - Blauw JTM
AUID- ORCID: 0000-0002-8974-5708
AD  - Department of Vascular Surgery, Medical Spectrum Twente, Enschede, Netherlands.
AD  - Department of Surgery, Leiden University Medical Center, Leiden, Netherlands.
FAU - Pastoors, H A M
AU  - Pastoors HAM
AD  - Department of Vascular Surgery, Medical Spectrum Twente, Enschede, Netherlands.
FAU - Brusse-Keizer, M
AU  - Brusse-Keizer M
AD  - Medical School Twente, Medisch Spectrum Twente, Enschede, Netherlands.
FAU - Beuk, R J
AU  - Beuk RJ
AD  - Department of Vascular Surgery, Medical Spectrum Twente, Enschede, Netherlands.
FAU - Kolkman, J J
AU  - Kolkman JJ
AD  - Department of Gastroenterology, Medisch Spectrum Twente, University Medical 
      Center Groningen, Enschede, Netherlands.
FAU - Geelkerken, R H
AU  - Geelkerken RH
AD  - Department of Vascular Surgery, Medical Spectrum Twente, Enschede, Netherlands.
AD  - Multimodality Medical Imaging M3i Group, Faculty of Science and Technology, 
      Technical Medical Centre, University of Twente, Enschede, Netherlands.
FAU - For The Dutch Mesenteric Ischemia Study Group
AU  - For The Dutch Mesenteric Ischemia Study Group
AD  - Medisch Spectrum Twente (t.n.v. R.H. Geelkerken, Backoffice Chirurgie B11), 
      Postbus 50.000, 7500 KA, Enschede, Netherlands.
LA  - eng
PT  - Journal Article
DEP - 20191112
PL  - Egypt
TA  - Can J Gastroenterol Hepatol
JT  - Canadian journal of gastroenterology & hepatology
JID - 101623613
SB  - IM
MH  - Adult
MH  - Aged
MH  - Chronic Disease
MH  - Female
MH  - Humans
MH  - Male
MH  - Mesenteric Ischemia/psychology/*surgery
MH  - Middle Aged
MH  - *Quality of Life
MH  - Recovery of Function
MH  - Retrospective Studies
MH  - Surveys and Questionnaires
MH  - Treatment Outcome
PMC - PMC6874997
COIS- The authors declare that they have no conflicts of interest.
EDAT- 2019/11/30 06:00
MHDA- 2020/05/30 06:00
PMCR- 2019/11/12
CRDT- 2019/11/30 06:00
PHST- 2019/02/11 00:00 [received]
PHST- 2019/08/29 00:00 [accepted]
PHST- 2019/11/30 06:00 [entrez]
PHST- 2019/11/30 06:00 [pubmed]
PHST- 2020/05/30 06:00 [medline]
PHST- 2019/11/12 00:00 [pmc-release]
AID - 10.1155/2019/7346013 [doi]
PST - epublish
SO  - Can J Gastroenterol Hepatol. 2019 Nov 12;2019:7346013. doi: 10.1155/2019/7346013. 
      eCollection 2019.