PMID- 31782108
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240328
IS  - 1568-5888 (Print)
IS  - 1876-6250 (Electronic)
IS  - 1568-5888 (Linking)
VI  - 28
IP  - 3
DP  - 2020 Mar
TI  - Prophylactic veno-arterial extracorporeal membrane oxygenation in patients 
      undergoing high-risk percutaneous coronary intervention.
PG  - 139-144
LID - 10.1007/s12471-019-01350-8 [doi]
AB  - PURPOSE: Complex high-risk percutaneous coronary intervention (PCI) is 
      challenging and frequently accompanied by haemodynamic instability. Veno-arterial 
      extracorporeal membrane oxygenation (VA-ECMO) can provide cardiopulmonary support 
      in high-risk PCI. However, the outcome is unclear. METHODS: A two-centre, 
      retrospective study was performed of all patients undergoing high-risk PCI and 
      receiving VA-ECMO for cardiopulmonary support. RESULTS: A total of 14 patients 
      (92% male, median age 69 (53-83) years), of whom 50% had previous coronary artery 
      disease in the form of a coronary artery bypass graft (36%) and a PCI (14%) 
      underwent high-risk PCI and received VA-ECMO support. The main target lesion was 
      a left main coronary artery in 78%, a left anterior descending artery in 14%, 
      a right coronary artery in 7%, and 71% underwent multi-vessel PCI in addition to 
      main target vessel PCI. The median SYNTAX score was 27.2 (8-42.5) and in 64% 
      (9/14) there was a chronic total occlusion. Left ventricular function was mildly 
      impaired in 7% (1/14), moderately impaired in 14% (2/14) and severely impaired in 
      64% (9/14). Cannulation was femoral-femoral in all patients. Median ECMO run was 
      2.57 h (1-4). Survival was 93% (13/14). One patient died during hospitalisation 
      due to refractory cardiac failure. All other patients survived to discharge. 
      Complications occurred in 14% (2/14), with one patient developing a transient 
      ischaemic attack post-ECMO and one patient developing a thrombus in the femoral 
      vein used for ECMO cannulation. CONCLUSION: VA-ECMO in high-risk PCI is feasible 
      with a good outcome. It can be successfully used for cardiopulmonary support in 
      selected patients.
FAU - van den Brink, F S
AU  - van den Brink FS
AD  - Department of Cardiology, Medisch Centrum Leeuwarden, Leeuwarden, The 
      Netherlands. floris.s.van.den.brink@gmail.com.
FAU - Meijers, T A
AU  - Meijers TA
AD  - Department of Cardiology, Location Vrije Universiteit Medisch Centrum, Amsterdam 
      Universitair Medisch Centrum, Amsterdam, The Netherlands.
FAU - Hofma, S H
AU  - Hofma SH
AD  - Department of Cardiology, Medisch Centrum Leeuwarden, Leeuwarden, The 
      Netherlands.
FAU - van Boven, A J
AU  - van Boven AJ
AD  - Department of Cardiology, Medisch Centrum Leeuwarden, Leeuwarden, The 
      Netherlands.
FAU - Nap, A
AU  - Nap A
AD  - Department of Cardiology, Location Vrije Universiteit Medisch Centrum, Amsterdam 
      Universitair Medisch Centrum, Amsterdam, The Netherlands.
FAU - Vonk, A
AU  - Vonk A
AD  - Department of Cardiology, Location Vrije Universiteit Medisch Centrum, Amsterdam 
      Universitair Medisch Centrum, Amsterdam, The Netherlands.
FAU - Symersky, P
AU  - Symersky P
AD  - Department of Cardio-Thoracic Surgery, Location Vrije Universiteit Medisch 
      Centrum, Amsterdam Universitair Medisch Centrum, Amsterdam, The Netherlands.
FAU - Sjauw, K D
AU  - Sjauw KD
AD  - Department of Cardiology, Medisch Centrum Leeuwarden, Leeuwarden, The 
      Netherlands.
FAU - Knaapen, P
AU  - Knaapen P
AD  - Department of Cardiology, Location Vrije Universiteit Medisch Centrum, Amsterdam 
      Universitair Medisch Centrum, Amsterdam, The Netherlands.
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Neth Heart J
JT  - Netherlands heart journal : monthly journal of the Netherlands Society of 
      Cardiology and the Netherlands Heart Foundation
JID - 101095458
PMC - PMC7052097
OTO - NOTNLM
OT  - Chronic total occlusion
OT  - High-risk percutaneous coronary intervention
OT  - Percutaneous coronary intervention
OT  - Veno-arterial extracorporeal membrane oxygenation
COIS- F.S. van den Brink, T.A. Meijers, S.H. Hofma, A.J. van Boven, A. Nap, A. Vonk, 
      P. Symersky, K.D. Sjauw and P. Knaapen declare that they have no competing 
      interests.
EDAT- 2019/11/30 06:00
MHDA- 2019/11/30 06:01
PMCR- 2019/11/28
CRDT- 2019/11/30 06:00
PHST- 2019/11/30 06:00 [pubmed]
PHST- 2019/11/30 06:01 [medline]
PHST- 2019/11/30 06:00 [entrez]
PHST- 2019/11/28 00:00 [pmc-release]
AID - 10.1007/s12471-019-01350-8 [pii]
AID - 1350 [pii]
AID - 10.1007/s12471-019-01350-8 [doi]
PST - ppublish
SO  - Neth Heart J. 2020 Mar;28(3):139-144. doi: 10.1007/s12471-019-01350-8.