PMID- 31783791 OWN - NLM STAT- MEDLINE DCOM- 20200630 LR - 20200630 IS - 1471-2261 (Electronic) IS - 1471-2261 (Linking) VI - 19 IP - 1 DP - 2019 Nov 28 TI - Rationale and design of the Henan ST elevation myocardial infarction (STEMI) registry: a regional STEMI project in predominantly rural central China. PG - 271 LID - 10.1186/s12872-019-1250-9 [doi] LID - 271 AB - BACKGROUND: Cardiovascular disease including ST elevation myocardial infarction (STEMI) is increasing and the leading cause of death in China. There has been limited data available to characterize STEMI management and outcomes in rural areas of China. The Henan STEMI Registry is a regional STEMI project with the objectives to timely obtain real-world knowledge about STEMI patients in secondary and tertiary hospitals and to provide a platform for care quality improvement efforts in predominantly rural central China. METHODS: The Henan STEMI Registry is a multicentre, prospective and observational study for STEMI patients. The registry includes 66 participating hospitals (50 secondary hospitals; 16 tertiary hospitals) that cover 15 prefectures and one city direct-controlled by the province in Henan province. Patients were consecutively enrolled with a primary diagnosis of STEMI within 30 days of symptom onset. Clinical treatments, outcomes and cost are collected by local investigators and captured electronically, with a standardized set of variables and standard definitions, and rigorous data quality control. Post-discharge patient follow-up to 1 year is planned. As of August 2018, the Henan STEMI Registry has enrolled 5479 patients of STEMI. DISCUSSION: The Henan STEMI Registry represents the largest Chinese regional platform for clinical research and care quality improvement for STEMI. The board inclusion of secondary hospitals in Henan province will allow for the exploration of STEMI in predominantly rural central China. TRIAL REGISTRATION: [NCT02641262] [29 December, 2015]. FAU - Zhang, You AU - Zhang Y AD - Department of Cardiology, Zhengzhou University People's Hospital, No. 1 Fuwai Road, Zhengzhou, 450018, Henan, China. AD - Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou, Henan, China. AD - Department of Cardiology, Central China Fuwai Hospital, Zhengzhou, Henan, China. AD - Henan Institute of Cardiovascular Epidemiology, Zhengzhou, Henan, China. FAU - Wang, Shan AU - Wang S AD - Department of Cardiology, Zhengzhou University People's Hospital, No. 1 Fuwai Road, Zhengzhou, 450018, Henan, China. AD - Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou, Henan, China. AD - Department of Cardiology, Central China Fuwai Hospital, Zhengzhou, Henan, China. AD - Henan Institute of Cardiovascular Epidemiology, Zhengzhou, Henan, China. FAU - Yang, Shuyan AU - Yang S AD - Department of Electrocardiography, Henan Chest Hospital, Zhengzhou, Henan, China. FAU - Yin, Shanshan AU - Yin S AD - Henan Academy of Medical Sciences, Zhengzhou, Henan, China. FAU - Cheng, Qianqian AU - Cheng Q AD - Department of Cardiology, Zhengzhou University People's Hospital, No. 1 Fuwai Road, Zhengzhou, 450018, Henan, China. AD - Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou, Henan, China. AD - Department of Cardiology, Central China Fuwai Hospital, Zhengzhou, Henan, China. AD - Henan Institute of Cardiovascular Epidemiology, Zhengzhou, Henan, China. FAU - Li, Muwei AU - Li M AD - Department of Cardiology, Zhengzhou University People's Hospital, No. 1 Fuwai Road, Zhengzhou, 450018, Henan, China. AD - Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou, Henan, China. AD - Department of Cardiology, Central China Fuwai Hospital, Zhengzhou, Henan, China. FAU - Qi, Datun AU - Qi D AD - Department of Cardiology, Zhengzhou University People's Hospital, No. 1 Fuwai Road, Zhengzhou, 450018, Henan, China. AD - Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou, Henan, China. AD - Department of Cardiology, Central China Fuwai Hospital, Zhengzhou, Henan, China. FAU - Wang, Xianpei AU - Wang X AD - Department of Cardiology, Zhengzhou University People's Hospital, No. 1 Fuwai Road, Zhengzhou, 450018, Henan, China. AD - Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou, Henan, China. AD - Department of Cardiology, Central China Fuwai Hospital, Zhengzhou, Henan, China. FAU - Zhu, Zhongyu AU - Zhu Z AD - Department of Cardiology, Zhengzhou University People's Hospital, No. 1 Fuwai Road, Zhengzhou, 450018, Henan, China. AD - Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou, Henan, China. AD - Department of Cardiology, Central China Fuwai Hospital, Zhengzhou, Henan, China. FAU - Zhao, Luosha AU - Zhao L AD - Department of Cardiology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. FAU - Hu, Dayi AU - Hu D AD - Henan Institute of Cardiovascular Epidemiology, Zhengzhou, Henan, China. AD - Heart centre, Peking University People's Hospital, Beijing, China. FAU - Gao, Chuanyu AU - Gao C AUID- ORCID: 0000-0002-9608-9438 AD - Department of Cardiology, Zhengzhou University People's Hospital, No. 1 Fuwai Road, Zhengzhou, 450018, Henan, China. gaocy6802@126.com. AD - Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou, Henan, China. gaocy6802@126.com. AD - Department of Cardiology, Central China Fuwai Hospital, Zhengzhou, Henan, China. gaocy6802@126.com. AD - Henan Institute of Cardiovascular Epidemiology, Zhengzhou, Henan, China. gaocy6802@126.com. LA - eng SI - ClinicalTrials.gov/NCT02641262 PT - Journal Article PT - Multicenter Study PT - Observational Study PT - Research Support, Non-U.S. Gov't DEP - 20191128 PL - England TA - BMC Cardiovasc Disord JT - BMC cardiovascular disorders JID - 100968539 SB - IM MH - China/epidemiology MH - Cost-Benefit Analysis MH - Female MH - Health Care Costs MH - Humans MH - Male MH - Prospective Studies MH - *Quality Improvement/economics MH - *Quality Indicators, Health Care/economics MH - Registries MH - Research Design MH - *Rural Health Services/economics MH - ST Elevation Myocardial Infarction/diagnosis/economics/mortality/*therapy MH - Time Factors MH - Treatment Outcome PMC - PMC6883687 OTO - NOTNLM OT - China OT - Mortality OT - Quality improvement OT - Registry OT - Rural health OT - ST elevation myocardial infarction COIS- The authors declare that they have no competing interests. EDAT- 2019/12/01 06:00 MHDA- 2020/07/01 06:00 PMCR- 2019/11/28 CRDT- 2019/12/01 06:00 PHST- 2019/06/05 00:00 [received] PHST- 2019/11/11 00:00 [accepted] PHST- 2019/12/01 06:00 [entrez] PHST- 2019/12/01 06:00 [pubmed] PHST- 2020/07/01 06:00 [medline] PHST- 2019/11/28 00:00 [pmc-release] AID - 10.1186/s12872-019-1250-9 [pii] AID - 1250 [pii] AID - 10.1186/s12872-019-1250-9 [doi] PST - epublish SO - BMC Cardiovasc Disord. 2019 Nov 28;19(1):271. doi: 10.1186/s12872-019-1250-9.