PMID- 31786746
OWN - NLM
STAT- MEDLINE
DCOM- 20210610
LR  - 20210610
IS  - 1522-1709 (Electronic)
IS  - 1520-9512 (Linking)
VI  - 24
IP  - 2
DP  - 2020 Jun
TI  - Effectiveness of barbed repositioning pharyngoplasty for the treatment of 
      obstructive sleep apnea (OSA): a prospective randomized trial.
PG  - 687-694
LID - 10.1007/s11325-019-01956-7 [doi]
AB  - PURPOSE: The aim of our randomized clinical trial is to produce stronger evidence 
      supporting barbed repositioning pharyngoplasty (BRP) as a therapeutic option for 
      the treatment of obstructive sleep apnea (OSA). METHODS: The trial was a 
      single-center prospective controlled trial with two parallel arms (group A: BRP; 
      group B: observation) and randomization. Baseline and 6-month polygraphy 
      evaluating the apnea hypopnea index (AHI), oxygen desaturation index (ODI), and 
      lowest oxygen saturation (LOS) were performed. To test the differences among 
      groups of Student's t test, the role of each factor (univariate analysis) and 
      their independent effect (multivariate analysis) was explored using logistic 
      regression model as appropriate. Linear regression was also conducted. RESULTS: A 
      significant reduction of AHI, ODI, LOS, and Epworth Sleepiness Scale (ESS) values 
      was recorded in the BRP group. BRP showed to be more effective than observation. 
      Logistic regression showed that preoperative AHI is related significantly to 
      postoperative AHI within the BRP group. A linear regression showed that higher 
      baseline AHI predicts more significant postoperative absolute AHI reduction. 
      CONCLUSIONS: BRP appears to be a promising technique and might be included within 
      the surgical armamentarium of a sleep surgeon. Patients affected by severe OSA 
      may benefit from this surgery with more significant reduction of AHI values.
FAU - Vicini, Claudio
AU  - Vicini C
AD  - Unit of Otolaryngology, Hospital Morgagni Pierantoni, Forli, Italy.
AD  - Unit of Otolaryngology, University of Ferrara, Ferrara, Italy.
FAU - Meccariello, Giuseppe
AU  - Meccariello G
AD  - Unit of Otolaryngology, Hospital Morgagni Pierantoni, Forli, Italy.
FAU - Montevecchi, Filippo
AU  - Montevecchi F
AD  - Unit of Otolaryngology, Hospital Morgagni Pierantoni, Forli, Italy.
FAU - De Vito, Andrea
AU  - De Vito A
AD  - Unit of Otolaryngology, Hospital Morgagni Pierantoni, Forli, Italy.
FAU - Frassineti, Sabrina
AU  - Frassineti S
AD  - Unit of Otolaryngology, Hospital Morgagni Pierantoni, Forli, Italy.
FAU - Gobbi, Riccardo
AU  - Gobbi R
AD  - Unit of Otolaryngology, Hospital Morgagni Pierantoni, Forli, Italy.
FAU - Pelucchi, Stefano
AU  - Pelucchi S
AD  - Unit of Otolaryngology, University of Ferrara, Ferrara, Italy.
FAU - Iannella, Giannicola
AU  - Iannella G
AD  - Unit of Otolaryngology, La Sapienza University, Rome, Italy.
FAU - Magliulo, Giuseppe
AU  - Magliulo G
AD  - Unit of Otolaryngology, La Sapienza University, Rome, Italy.
FAU - Cammaroto, Giovanni
AU  - Cammaroto G
AUID- ORCID: 0000-0002-1618-0048
AD  - Unit of Otolaryngology, Hospital Morgagni Pierantoni, Forli, Italy. 
      giovanni.cammaroto@hotmail.com.
AD  - Unit of Otolaryngology, University of Messina, Messina, Italy. 
      giovanni.cammaroto@hotmail.com.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20191130
PL  - Germany
TA  - Sleep Breath
JT  - Sleep & breathing = Schlaf & Atmung
JID - 9804161
RN  - 0 (Hypnotics and Sedatives)
SB  - IM
MH  - Humans
MH  - *Hypnotics and Sedatives
MH  - Observer Variation
MH  - Oropharynx/surgery
MH  - Pharyngostomy/*methods
MH  - Pharynx/*surgery
MH  - Prospective Studies
MH  - Sleep Apnea, Obstructive/diagnosis/*surgery
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Barbed repositioning pharyngoplasty
OT  - OSA
OT  - OSAS
OT  - Outcome
OT  - Sleep surgery
EDAT- 2019/12/02 06:00
MHDA- 2021/06/11 06:00
CRDT- 2019/12/02 06:00
PHST- 2019/01/13 00:00 [received]
PHST- 2019/10/09 00:00 [accepted]
PHST- 2019/10/07 00:00 [revised]
PHST- 2019/12/02 06:00 [pubmed]
PHST- 2021/06/11 06:00 [medline]
PHST- 2019/12/02 06:00 [entrez]
AID - 10.1007/s11325-019-01956-7 [pii]
AID - 10.1007/s11325-019-01956-7 [doi]
PST - ppublish
SO  - Sleep Breath. 2020 Jun;24(2):687-694. doi: 10.1007/s11325-019-01956-7. Epub 2019 
      Nov 30.