PMID- 31793424
OWN - NLM
STAT- MEDLINE
DCOM- 20210111
LR  - 20210111
IS  - 2212-4012 (Electronic)
IS  - 1872-2083 (Linking)
VI  - 14
IP  - 2
DP  - 2020
TI  - Geminiviruses: Taxonomic Structure and Diversity in Genomic Organization.
PG  - 86-98
LID - 10.2174/1872208313666191203100851 [doi]
AB  - BACKGROUND: Geminiviridae is one of the best-characterized and hence, one of the 
      largest plant-virus families with the highest economic importance. Its members 
      characteristically have a circular ssDNA genome within the encapsidation of 
      twinned quasi-icosaheadral virions (18-38 nm size-range). OBJECTIVE: Construction 
      of a narrative review on geminiviruses, to have a clearer picture of their 
      genomic structure and taxonomic status. METHODS: A thorough search was conducted 
      for papers and patents regarding geminiviruses, where relevant information was 
      used to study their genomic organization, diversity and taxonomic structure. 
      RESULTS: Geminiviruses have been classified into nine genera (viz., genus 
      Begomovirus, Mastrevirus, Curtovirus, Topocuvirus, Becurtovirus, Turncurtovirus, 
      Capulavirus, Eragrovirus and Grablovirus) having distinct genomic organizations, 
      host ranges and insect vectors. Genomic organization of all genera generally 
      shows the presence of 4-6 ORFs encoding for various proteins. For now, Citrus 
      chlorotic dwarf-associated virus (CCDaV), Camellia chlorotic dwarf-associated 
      virus (CaCDaV) and few other geminiviruses are still unassigned to any genera. 
      The monopartite begomoviruses (and few mastreviruses) have been found associated 
      with aplhasatellites and betasatellites (viz., ~1.3 kb circular ssDNA 
      satellites). Recent reports suggest that deltasatellites potentially reduce the 
      accumulation of helper-Begomovirus species in host plants. Some patents have 
      revealed the methods to generate transgenic plants resistant to geminiviruses. 
      CONCLUSION: Geminiviruses rapidly evolve and are a highly diverse group of 
      plant-viruses. However, research has shown new horizons in tackling the acute 
      begomoviral diseases in plants by generating a novel bio-control methodology in 
      which deltasatellites can be used as bio-control agents and generate transgenic 
      plants resistant to geminiviruses.
CI  - Copyright(c) Bentham Science Publishers; For any queries, please email at 
      epub@benthamscience.net.
FAU - Kulshrestha, Saurabh
AU  - Kulshrestha S
AD  - School of Biotechnology, Faculty of Applied Sciences and Biotechnology, Shoolini 
      University of Biotechnology and Management Sciences, Bajhol, Solan (H.P.), India.
FAU - Bhardwaj, Abhishek
AU  - Bhardwaj A
AD  - School of Biotechnology, Faculty of Applied Sciences and Biotechnology, Shoolini 
      University of Biotechnology and Management Sciences, Bajhol, Solan (H.P.), India.
FAU - Vanshika
AU  - Vanshika
AD  - School of Biotechnology, Faculty of Applied Sciences and Biotechnology, Shoolini 
      University of Biotechnology and Management Sciences, Bajhol, Solan (H.P.), India.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United Arab Emirates
TA  - Recent Pat Biotechnol
JT  - Recent patents on biotechnology
JID - 101309942
RN  - 0 (DNA, Single-Stranded)
RN  - 0 (DNA, Viral)
SB  - IM
MH  - DNA, Single-Stranded/genetics
MH  - DNA, Viral/genetics
MH  - Geminiviridae/*classification/*genetics
MH  - Genome, Viral/genetics
MH  - Patents as Topic
OTO - NOTNLM
OT  - Geminiviridae
OT  - aplhasatellites
OT  - begomoviruses
OT  - betasatellites
OT  - deltasatellites
OT  - ssDNA.
EDAT- 2019/12/04 06:00
MHDA- 2021/01/12 06:00
CRDT- 2019/12/04 06:00
PHST- 2019/08/27 00:00 [received]
PHST- 2019/11/04 00:00 [revised]
PHST- 2019/11/25 00:00 [accepted]
PHST- 2019/12/04 06:00 [pubmed]
PHST- 2021/01/12 06:00 [medline]
PHST- 2019/12/04 06:00 [entrez]
AID - BIOT-EPUB-102720 [pii]
AID - 10.2174/1872208313666191203100851 [doi]
PST - ppublish
SO  - Recent Pat Biotechnol. 2020;14(2):86-98. doi: 10.2174/1872208313666191203100851.