PMID- 31802198 OWN - NLM STAT- MEDLINE DCOM- 20211124 LR - 20211124 IS - 1432-0460 (Electronic) IS - 0179-051X (Linking) VI - 35 IP - 5 DP - 2020 Oct TI - An Absorbable Collagen Biomembrane Help Improve Swallowing Function After Anterior Cervical Spine Surgery. PG - 780-786 LID - 10.1007/s00455-019-10083-0 [doi] AB - The objective of this study is to investigate the changes in swallowing function after using an absorbable collagen biomembrane during anterior cervical spine surgery (ACSS). A prospective controlled study of patients who underwent two-level anterior cervical decompression and fusion (ACDF) with a zero-profile implant or single-level anterior cervical corpectomy and fusion (ACCF) with cage and plate fixation was performed in our hospital from January 2016. An absorbable collagen biomembrane was used after suturing the prevertebral fascia in the experimental groups. The thickness of prevertebral soft tissue (PST) was measured on lateral X-rays to determine the extent of swelling. In addition, the Bazaz grading system and the Swallowing-Quality of Life (SWAL-QOL) survey were used to assess the swallowing function. A total of 100 patients were included with a follow-up of 12 months. Significant differences in PST swelling were found between the experimental groups and control groups at 3 months, 6 months, and 12 months postoperatively (P < 0.05). Patients in the experimental groups had significantly increased SWAL-QOL scores compared with patients in the control groups at 3 months and 6 months after surgery (P < 0.05). A significant difference in the total incidence of dysphagia was observed at 3 months postoperatively between the experimental groups and control groups (P < 0.05). The application of absorbable collagen biomembrane in ACSS can reduce the total incidence of dysphagia and improve swallowing function early after surgery. FAU - Deng, Yuxiao AU - Deng Y AD - Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. FAU - Huang, Kangkang AU - Huang K AD - Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. FAU - Liu, Hao AU - Liu H AD - Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. FAU - Chen, Hua AU - Chen H AD - Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. FAU - Rong, Xin AU - Rong X AD - Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. FAU - Gong, Quan AU - Gong Q AD - Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. FAU - Hong, Ying AU - Hong Y AUID- ORCID: 0000-0003-0925-4560 AD - Department of Operation Room, West China Hospital, Sichuan University, 37# Guoxue Lane, Chengdu, 610041, Sichuan, China. hongyin518@126.com. FAU - Yang, Yi AU - Yang Y AD - Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. LA - eng GR - 81572141/National Natural Science Foundation of China/International PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20191204 PL - United States TA - Dysphagia JT - Dysphagia JID - 8610856 RN - 9007-34-5 (Collagen) SB - IM MH - Cervical Vertebrae/surgery MH - Collagen MH - Deglutition MH - *Deglutition Disorders/etiology MH - Diskectomy MH - Humans MH - Postoperative Complications MH - Prospective Studies MH - Quality of Life MH - Retrospective Studies MH - *Spinal Fusion MH - Treatment Outcome OTO - NOTNLM OT - Absorbable collagen biomembrane OT - Anterior cervical spine surgery (ACSS) OT - Deglutition OT - Deglutition disorders OT - Dysphagia OT - Swallowing-Quality of Life (SWAL-QOL) survey EDAT- 2019/12/06 06:00 MHDA- 2021/11/25 06:00 CRDT- 2019/12/06 06:00 PHST- 2019/03/15 00:00 [received] PHST- 2019/11/25 00:00 [accepted] PHST- 2019/12/06 06:00 [pubmed] PHST- 2021/11/25 06:00 [medline] PHST- 2019/12/06 06:00 [entrez] AID - 10.1007/s00455-019-10083-0 [pii] AID - 10.1007/s00455-019-10083-0 [doi] PST - ppublish SO - Dysphagia. 2020 Oct;35(5):780-786. doi: 10.1007/s00455-019-10083-0. Epub 2019 Dec 4.