PMID- 31802441 OWN - NLM STAT- MEDLINE DCOM- 20200527 LR - 20200527 IS - 0975-0711 (Electronic) IS - 0254-8860 (Linking) VI - 38 IP - 5 DP - 2019 Oct TI - Indian consensus on gastroesophageal reflux disease in adults: A position statement of the Indian Society of Gastroenterology. PG - 411-440 LID - 10.1007/s12664-019-00979-y [doi] AB - The Indian Society of Gastroenterology developed this evidence-based practice guideline for management of gastroesophageal reflux disease (GERD) in adults. A modified Delphi process was used to develop this consensus containing 58 statements, which were generated by electronic voting iteration as well as face-to-face meeting and review of the supporting literature primarily from India. These statements include 10 on epidemiology, 8 on clinical presentation, 10 on investigations, 23 on treatment (including medical, endoscopic, and surgical modalities), and 7 on complications of GERD. When the proportion of those who voted either to accept completely or with minor reservation was 80% or higher, the statement was regarded as accepted. The prevalence of GERD in India ranges from 7.6% to 30%, being < 10% in most population studies, and higher in cohort studies. The dietary factors associated with GERD include use of spices and non-vegetarian food. Helicobacter pylori is thought to have a negative relation with GERD; H. pylori negative patients have higher grade of symptoms of GERD and esophagitis. Less than 10% of GERD patients in India have erosive esophagitis. In patients with occasional or mild symptoms, antacids and histamine H(2) receptor blockers (H2RAs) may be used, and proton pump inhibitors (PPI) should be used in patients with frequent or severe symptoms. Prokinetics have limited proven role in management of GERD. FAU - Bhatia, Shobna J AU - Bhatia SJ AD - Seth GS Medical College and KEM Hospital, Mumbai, 400 012, India. shobna.bhatia@gmail.com. FAU - Makharia, Govind K AU - Makharia GK AD - All India Institute of Medical Sciences, New Delhi, 110 029, India. FAU - Abraham, Philip AU - Abraham P AD - P D Hinduja Hospital and MRC, and Hinduja Heathcare Surgical, Mumbai, 400 016, India. FAU - Bhat, Naresh AU - Bhat N AD - Aster CMI Hospital, Bengaluru, 560 092, India. FAU - Kumar, Ajay AU - Kumar A AD - Fortis Escorts Liver and Digestive Diseases Institute, Delhi, 110 025, India. FAU - Reddy, D Nageshwar AU - Reddy DN AD - Asian Institute of Gastroenterology, Hyderabad, 500 082, India. FAU - Ghoshal, Uday C AU - Ghoshal UC AD - Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226 014, India. FAU - Ahuja, Vineet AU - Ahuja V AD - All India Institute of Medical Sciences, New Delhi, 110 029, India. FAU - Rao, G Venkat AU - Rao GV AD - Asian Institute of Gastroenterology, Hyderabad, 500 082, India. FAU - Devadas, Krishnadas AU - Devadas K AD - Government Medical College, Trivandrum, 695 011, India. FAU - Dutta, Amit K AU - Dutta AK AD - Christian Medical College, Vellore, 632 004, India. FAU - Jain, Abhinav AU - Jain A AD - Seth GS Medical College and KEM Hospital, Mumbai, 400 012, India. FAU - Kedia, Saurabh AU - Kedia S AD - All India Institute of Medical Sciences, New Delhi, 110 029, India. FAU - Dama, Rohit AU - Dama R AD - Asian Institute of Gastroenterology, Hyderabad, 500 082, India. FAU - Kalapala, Rakesh AU - Kalapala R AD - Asian Institute of Gastroenterology, Hyderabad, 500 082, India. FAU - Alvares, Jose Filipe AU - Alvares JF AD - Victor Hospital, Margao, Goa, 403 601, India. FAU - Dadhich, Sunil AU - Dadhich S AD - S N Medical College, Jodhpur, 342 003, India. FAU - Dixit, Vinod Kumar AU - Dixit VK AD - Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005, India. FAU - Goenka, Mahesh Kumar AU - Goenka MK AD - Appollo Gleneagles Hospitals, Kolkata, 700 054, India. FAU - Goswami, B D AU - Goswami BD AD - Gauhati Medical College, Dispur Hospitals, Guwahati, 781 032, India. FAU - Issar, Sanjeev K AU - Issar SK AD - JLN Hospital and Research Center, Bhilai Steel Plant, Bhilai, 490 009, India. FAU - Leelakrishnan, Venkatakrishnan AU - Leelakrishnan V AD - PSG Institute of Medical Sciences, Coimbatore, 641 002, India. FAU - Mallath, Mohandas K AU - Mallath MK AD - Tata Medical Center, Kolkata, 700 156, India. FAU - Mathew, Philip AU - Mathew P AD - PVS Memorial Hospital, Kochi, 682 017, India. FAU - Mathew, Praveen AU - Mathew P AD - Vydehi Institute of Medical Sciences and Research Centre, Bengaluru, 560 066, India. FAU - Nandwani, Subhashchandra AU - Nandwani S AD - Surat Institute of Digestive Sciences, Surat, 395 002, India. FAU - Pai, Cannanore Ganesh AU - Pai CG AD - Kasturba Medical College, Manipal Academy of Higher Education, Manipal, 576 104, India. FAU - Peter, Lorance AU - Peter L AD - Columbia Asia Hospital, Bengaluru, 560 075, India. FAU - Prasad, A V Siva AU - Prasad AVS AD - Institute of Gastroenterology, Visakhapatnam, 530 002, India. FAU - Singh, Devinder AU - Singh D AD - Apollo Hospitals, Bilaspur, 495 006, India. FAU - Sodhi, Jaswinder Singh AU - Sodhi JS AD - Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Kashmir, 190 001, India. FAU - Sud, Randhir AU - Sud R AD - Medanta - The Medicity, Gurugram, 122 001, India. FAU - Venkataraman, Jayanthi AU - Venkataraman J AD - Gleneagles Global Health City, Chennai, 600 100, India. FAU - Midha, Vandana AU - Midha V AD - Dayanand Medical College and Hospital, Ludhiana, 141 001, India. FAU - Bapaye, Amol AU - Bapaye A AD - Deenanath Mangeshkar Hospital and Research Center, Pune, 411 004, India. FAU - Dutta, Usha AU - Dutta U AD - Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India. FAU - Jain, Ajay K AU - Jain AK AD - Choithram Hospital and Research Centre, Indore, 452 014, India. FAU - Kochhar, Rakesh AU - Kochhar R AD - Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India. FAU - Puri, Amarender S AU - Puri AS AD - GB Pant Hospital, Delhi, 110 002, India. FAU - Singh, Shivram Prasad AU - Singh SP AD - S C B Medical College, Manglabag, Cuttack, 753 007, India. FAU - Shimpi, Lalit AU - Shimpi L AD - Jehangir Hospital, Pune, 411 001, India. FAU - Sood, Ajit AU - Sood A AD - Dayanand Medical College and Hospital, Ludhiana, 141 001, India. FAU - Wadhwa, Rajkumar T AU - Wadhwa RT AD - Apollo BGS Hospitals, Mysuru, 570 023, India. LA - eng GR - NA/Emcure Pharmaceuticals/International PT - Journal Article DEP - 20191205 PL - India TA - Indian J Gastroenterol JT - Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology JID - 8409436 RN - 0 (Antacids) RN - 0 (Histamine H2 Antagonists) RN - 0 (Proton Pump Inhibitors) SB - IM MH - Adult MH - Antacids/therapeutic use MH - Consensus MH - Diet/adverse effects MH - Esophagitis/epidemiology/etiology MH - Female MH - Gastroenterology/*standards MH - Gastroesophageal Reflux/*epidemiology/etiology/*therapy MH - Helicobacter Infections/complications MH - Helicobacter pylori MH - Histamine H2 Antagonists/therapeutic use MH - Humans MH - India/epidemiology MH - Male MH - *Practice Guidelines as Topic MH - Prevalence MH - Proton Pump Inhibitors/therapeutic use MH - Societies, Medical OTO - NOTNLM OT - Barrett's esophagus OT - Esophageal manometry OT - Esophageal pH monitoring OT - Proton pump inhibitors EDAT- 2019/12/06 06:00 MHDA- 2020/05/28 06:00 CRDT- 2019/12/06 06:00 PHST- 2019/03/10 00:00 [received] PHST- 2019/07/17 00:00 [accepted] PHST- 2019/12/06 06:00 [pubmed] PHST- 2020/05/28 06:00 [medline] PHST- 2019/12/06 06:00 [entrez] AID - 10.1007/s12664-019-00979-y [pii] AID - 10.1007/s12664-019-00979-y [doi] PST - ppublish SO - Indian J Gastroenterol. 2019 Oct;38(5):411-440. doi: 10.1007/s12664-019-00979-y. Epub 2019 Dec 5.