PMID- 31804128 OWN - NLM STAT- MEDLINE DCOM- 20210208 LR - 20210208 IS - 1949-2723 (Electronic) IS - 1949-2723 (Linking) VI - 11 IP - 3 DP - 2020 May TI - A meta-analysis of psychodynamic treatments for borderline and cluster C personality disorders. PG - 157-169 LID - 10.1037/per0000382 [doi] AB - Personality disorders (PD) carry high psychosocial dysfunction and are associated with treatment resistance in nonspecialized care. Psychodynamic therapies (PDT) are often used to treat PDs, but there has never been a systematic meta-analysis of PDT trials for PD. To evaluate the evidence base for PDTs for PDs across multiple outcome domain, a systematic search for PDT for PD trials was conducted through PubMed and PsycINFO. Sixteen trials were identified, comprising 19 dynamic, 8 active, and 9 control groups predominantly reflecting treatment of borderline and mixed Cluster C PDs, and a random effects meta-analysis was undertaken. PDTs were superior to controls in improving core PD symptoms (g = -0.63; 95% confidence interval [CI; -0.87, -0.41]), suicidality (g = -0.79, p = .02; 95% CI [-1.38, -0.20]), general psychiatric symptoms (g = -0.47; 95% CI [-0.69, -0.25]), and functioning (g = -0.66; 95% CI [-1.01, -0.32]), but not for interpersonal problems due to heterogeneity (g = -1.25; 95% CI [-3.22, 0.71]). Outcomes for PDTs were not different from other active treatments in core PD (g = 0.05; 95% CI [-0.25, 0.35]) or other symptoms. This pattern continued into posttreatment follow-up (average 14 months). Study quality was generally rated as adequate and was unrelated to outcomes. Compared with other treatments, PDTs do not have different acute effects and are superior to controls, although only trials treating BPD employed active controls and non-BPD trials were of lower quality. Underresearched areas include narcissistic PD, specific Cluster C disorders, and personality pathology as a continuous construct. (PsycInfo Database Record (c) 2020 APA, all rights reserved). FAU - Keefe, John R AU - Keefe JR AUID- ORCID: 0000-0001-7250-8960 AD - Department of Psychiatry. FAU - McMain, Shelley F AU - McMain SF AD - Department of Psychiatry. FAU - McCarthy, Kevin S AU - McCarthy KS AD - Department of Psychology. FAU - Zilcha-Mano, Sigal AU - Zilcha-Mano S AUID- ORCID: 0000-0002-5645-4429 AD - Department of Psychology. FAU - Dinger, Ulrike AU - Dinger U AD - Center for Psychosocial Medicine. FAU - Sahin, Zeynep AU - Sahin Z AUID- ORCID: 0000-0003-2010-4416 AD - Gordon F. Derner School of Psychology. FAU - Graham, Kathryn AU - Graham K AD - Gordon F. Derner School of Psychology. FAU - Barber, Jacques P AU - Barber JP AUID- ORCID: 0000-0002-8762-2595 AD - Gordon F. Derner School of Psychology. LA - eng GR - TR/NCATS NIH HHS/United States GR - TL1 TR002386/TR/NCATS NIH HHS/United States PT - Journal Article PT - Meta-Analysis PT - Research Support, N.I.H., Extramural PT - Systematic Review DEP - 20191205 PL - United States TA - Personal Disord JT - Personality disorders JID - 101517071 SB - IM MH - Borderline Personality Disorder/therapy MH - Clinical Trials as Topic MH - Humans MH - Personality Disorders/*therapy MH - *Psychotherapy, Psychodynamic EDAT- 2019/12/06 06:00 MHDA- 2021/02/09 06:00 CRDT- 2019/12/06 06:00 PHST- 2019/12/06 06:00 [pubmed] PHST- 2021/02/09 06:00 [medline] PHST- 2019/12/06 06:00 [entrez] AID - 2019-73147-001 [pii] AID - 10.1037/per0000382 [doi] PST - ppublish SO - Personal Disord. 2020 May;11(3):157-169. doi: 10.1037/per0000382. Epub 2019 Dec 5.