PMID- 31805334
OWN - NLM
STAT- MEDLINE
DCOM- 20210318
LR  - 20210318
IS  - 1879-0003 (Electronic)
IS  - 0141-8130 (Linking)
VI  - 157
DP  - 2020 Aug 15
TI  - Eco-friendly poly(lactic acid) microbeads for cosmetics via melt electrospraying.
PG  - 734-742
LID - S0141-8130(19)38922-6 [pii]
LID - 10.1016/j.ijbiomac.2019.11.240 [doi]
AB  - Microbeads (MBs) are essential materials for cosmetic and healthcare 
      applications. However, environmental pollution has recently emerged as a concern 
      due to the non-degradability and adsorption property of persistent organic 
      pollutants (POPs) in environmental conditions, particularly in the marine 
      environment. Therefore, the development of biodegradable MBs via eco-friendly 
      methods is urgently demanded. Poly(lactic acid) (PLA) is a biodegradable and 
      melt-processable aliphatic polyester which can be obtained from raw materials in 
      nature. In this study, the high molecular weight PLA was pre-treated by electron 
      beam (E-beam) irradiation in order to adjust the melt viscosity. Subsequently, 
      the PLA MBs were prepared by varying the processing parameters via an 
      eco-friendly melt electrospraying process. During the time, the PLA MBs showed 
      bulk degradation which lead to decrement of the residual weight, thermal and 
      structural stability. On the other hand, the crystallinity of PLA MBs was 
      significantly increased due to the degradation of amorphous region. Furthermore, 
      the PLA MBs showed poor POPs adsorption behavior compare with the commercial MBs 
      because of low specific surface area. From these results, the PLA MBs via green 
      method have a great potential to replace the non-degradable MBs in cosmetics.
CI  - Copyright (c) 2019 Elsevier B.V. All rights reserved.
FAU - Nam, Hyeong Chan
AU  - Nam HC
AD  - Department of Organic Materials Engineering, Chungnam National University, 
      Daejeon 34134, South Korea.
FAU - Park, Won Ho
AU  - Park WH
AD  - Department of Organic Materials Engineering, Chungnam National University, 
      Daejeon 34134, South Korea. Electronic address: parkwh@cnu.ac.kr.
LA  - eng
PT  - Journal Article
DEP - 20191202
PL  - Netherlands
TA  - Int J Biol Macromol
JT  - International journal of biological macromolecules
JID - 7909578
RN  - 0 (Biocompatible Materials)
RN  - 0 (Cosmetics)
RN  - 0 (Polyesters)
RN  - 459TN2L5F5 (poly(lactide))
SB  - IM
MH  - Biocompatible Materials/chemistry
MH  - Chemical Phenomena
MH  - Cosmetics/*chemistry
MH  - Hydrolysis
MH  - *Microspheres
MH  - Molecular Weight
MH  - Particle Size
MH  - Polyesters/*chemistry
MH  - Rheology
MH  - Viscosity
OTO - NOTNLM
OT  - Biodegradation
OT  - Cosmetics
OT  - Melt electrospraying
OT  - Microbeads
OT  - Poly(lactic acid)
EDAT- 2019/12/06 06:00
MHDA- 2021/03/19 06:00
CRDT- 2019/12/06 06:00
PHST- 2019/11/02 00:00 [received]
PHST- 2019/11/25 00:00 [revised]
PHST- 2019/11/30 00:00 [accepted]
PHST- 2019/12/06 06:00 [pubmed]
PHST- 2021/03/19 06:00 [medline]
PHST- 2019/12/06 06:00 [entrez]
AID - S0141-8130(19)38922-6 [pii]
AID - 10.1016/j.ijbiomac.2019.11.240 [doi]
PST - ppublish
SO  - Int J Biol Macromol. 2020 Aug 15;157:734-742. doi: 
      10.1016/j.ijbiomac.2019.11.240. Epub 2019 Dec 2.