PMID- 31812475
OWN - NLM
STAT- MEDLINE
DCOM- 20210108
LR  - 20210108
IS  - 1873-3336 (Electronic)
IS  - 0304-3894 (Linking)
VI  - 387
DP  - 2020 Apr 5
TI  - Selective binding of antibiotics using magnetic molecular imprint polymer (MMIP) 
      networks prepared from vinyl-functionalized magnetic nanoparticles.
PG  - 121709
LID - S0304-3894(19)31663-2 [pii]
LID - 10.1016/j.jhazmat.2019.121709 [doi]
AB  - Adverse effects of pharmaceutical emerging contaminants (PECs), including 
      antibiotics, in water supplies has been a global concern in recent years as they 
      threaten fresh water security and lead to serious health problems to human, 
      wildlife and the environment. However, detection of these contaminants in water 
      sources, as well as food products, is difficult due to their low concentration. 
      Here, we prepared a new family of magnetic molecular imprinted polymer (MMIP) 
      networks for binding antibiotics via a microemulsion polymerization technique 
      using vinyl silane modified Fe(3)O(4) magnetic nanoparticles. The cross-linked 
      polymer backbone successfully integrated with 20-30 nm magnetic nanoparticles and 
      generated a novel porous polymeric network structure. These networks showed a 
      high binding capacity for both templates, erythromycin and ciprofloxacin at 70 
      and 32 mg/g. Both MMIPs were also recyclable, retaining 75 % and 68 % of the 
      binding capacity after 4 cycles. These MMIPs have showed a clear preference for 
      binding the template molecules, with a binding capacity 4- to 7-fold higher than 
      the other antibiotics in the same matrix. These results demonstrate our MMIP 
      networks, which offered high binding capacity and selectivity as well as 
      recyclability, can be used for both removal and monitoring hazardous antibiotic 
      pollutants in different sources/samples and food products.
CI  - Copyright (c) 2019 Elsevier B.V. All rights reserved.
FAU - Kuhn, Joel
AU  - Kuhn J
AD  - Chemical Engineering, School of Engineering and Physical Sciences, Heriot-Watt 
      University, Edinburgh, EH14 4AS, UK.
FAU - Aylaz, Gulgun
AU  - Aylaz G
AD  - Nanotechnology and Nanomedicine Division, Institute of Science, Hacettepe 
      University, Ankara, Turkey.
FAU - Sari, Esma
AU  - Sari E
AD  - Vocational School of Health Services, Medical Laboratory Techniques, Yuksek 
      Ihtisas University, Ankara, Turkey.
FAU - Marco, Mariano
AU  - Marco M
AD  - Chemical Engineering, School of Engineering and Physical Sciences, Heriot-Watt 
      University, Edinburgh, EH14 4AS, UK.
FAU - Yiu, Humphrey H P
AU  - Yiu HHP
AD  - Chemical Engineering, School of Engineering and Physical Sciences, Heriot-Watt 
      University, Edinburgh, EH14 4AS, UK. Electronic address: h.h.yiu@hw.ac.uk.
FAU - Duman, Memed
AU  - Duman M
AD  - Nanotechnology and Nanomedicine Division, Institute of Science, Hacettepe 
      University, Ankara, Turkey. Electronic address: memi@hacettepe.edu.tr.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20191121
PL  - Netherlands
TA  - J Hazard Mater
JT  - Journal of hazardous materials
JID - 9422688
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Magnetite Nanoparticles)
RN  - 0 (Polyvinyls)
RN  - 0 (Water Pollutants, Chemical)
RN  - 5E8K9I0O4U (Ciprofloxacin)
RN  - 63937KV33D (Erythromycin)
SB  - IM
MH  - Anti-Bacterial Agents/*isolation & purification
MH  - Ciprofloxacin/*isolation & purification
MH  - Erythromycin/*isolation & purification
MH  - Food Contamination
MH  - Limit of Detection
MH  - Magnetite Nanoparticles/*chemistry
MH  - *Molecular Imprinting
MH  - Polyvinyls/chemical synthesis/*chemistry
MH  - Water Pollutants, Chemical/isolation & purification
OTO - NOTNLM
OT  - 3-butenyltriethoxysilane
OT  - Ciprofloxacin CPX
OT  - Erythromycin ERY
OT  - Magnetic MIP
OT  - Poly(methacrylic acid) PMAA
COIS- Declaration of Competing Interest There is no conflict of interest to declare.
EDAT- 2019/12/10 06:00
MHDA- 2021/01/09 06:00
CRDT- 2019/12/09 06:00
PHST- 2019/09/20 00:00 [received]
PHST- 2019/11/14 00:00 [revised]
PHST- 2019/11/15 00:00 [accepted]
PHST- 2019/12/10 06:00 [pubmed]
PHST- 2021/01/09 06:00 [medline]
PHST- 2019/12/09 06:00 [entrez]
AID - S0304-3894(19)31663-2 [pii]
AID - 10.1016/j.jhazmat.2019.121709 [doi]
PST - ppublish
SO  - J Hazard Mater. 2020 Apr 5;387:121709. doi: 10.1016/j.jhazmat.2019.121709. Epub 
      2019 Nov 21.