PMID- 31816922 OWN - NLM STAT- MEDLINE DCOM- 20200630 LR - 20221207 IS - 2072-6643 (Electronic) IS - 2072-6643 (Linking) VI - 11 IP - 12 DP - 2019 Dec 3 TI - Association of DASH and Depressive Symptoms with BMI over Adulthood in Racially and Socioeconomically Diverse Adults Examined in the HANDLS Study. LID - 10.3390/nu11122934 [doi] LID - 2934 AB - Adherence to the Dietary Approaches to Stop Hypertension (DASH) diet is linked to slower weight gain over time. Elevated depressive symptoms may lead to poor quality diets, potentially increasing Body Mass Index (BMI). This study explored these pathways using longitudinal data extracted from 1201-1458 Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study participants. DASH mean score was computed using four 24 h recalls [visits(v)1 + v2/2: 2004-2013] and depressive symptoms using the Center for Epidemiologic Studies Depression (CES-D) scale (v1 + v2/2: 2004-2013). BMI was measured at v2: 2009-2013 and v3: 2013-2017. Multiple linear mixed regression and mediation modeling were conducted, linking CES-D((mean)) and DASH((mean)) to BMI [v2 and annualized change DeltaBMI (v3-v2)] and exploring mediation of the CES-D((mean))-BMI((v3)) and DASH((mean))-BMI((v3)) associations through DASH((mean)) and CES-D((mean)), respectively. Models were further stratified by sex, race and poverty status. Inverse cross-sectional and longitudinal relationships of DASH((mean)) with BMI((v2)) and DeltaBMI were detected, mainly in women and <125% of poverty participants. CES-D((mean)) was not associated with BMI((v3)); no mediation was detected through DASH((mean)) in all socio-demographic strata. Moreover, the inverse DASH((mean))-BMI((v3)) total effect was not mediated through CES-D((mean)). Future studies should explore other pathways aside from depressive symptoms by which DASH can have a preventive effect on weight status over time. FAU - Fanelli Kuczmarski, Marie AU - Fanelli Kuczmarski M AUID- ORCID: 0000-0001-6903-3386 AD - Department of Behavioral Health and Nutrition, University of Delaware, 206C McDowell Hall, Newark, DE 19716, USA. FAU - Hossain, Sharmin AU - Hossain S AD - Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institute of Health, Baltimore, MD 21224, USA. FAU - Beydoun, May A AU - Beydoun MA AUID- ORCID: 0000-0002-1050-4523 AD - Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institute of Health, Baltimore, MD 21224, USA. FAU - Maldonando, Ana AU - Maldonando A AD - Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institute of Health, Baltimore, MD 21224, USA. FAU - Evans, Michele K AU - Evans MK AD - Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institute of Health, Baltimore, MD 21224, USA. FAU - Zonderman, Alan B AU - Zonderman AB AD - Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institute of Health, Baltimore, MD 21224, USA. LA - eng GR - Z01-AG000513/AG/NIA NIH HHS/United States PT - Journal Article DEP - 20191203 PL - Switzerland TA - Nutrients JT - Nutrients JID - 101521595 SB - IM MH - Adult MH - Black or African American/*psychology MH - Body Mass Index MH - Depressive Disorder/*complications MH - *Dietary Approaches To Stop Hypertension MH - Female MH - *Healthy Aging MH - Humans MH - Male MH - Middle Aged MH - *Residence Characteristics MH - *Socioeconomic Factors MH - White People/*psychology PMC - PMC6950765 OTO - NOTNLM OT - DASH diet OT - body mass index OT - depressive symptoms OT - urban adults COIS- The authors declare no conflict of interest. EDAT- 2019/12/11 06:00 MHDA- 2020/07/01 06:00 PMCR- 2019/12/01 CRDT- 2019/12/11 06:00 PHST- 2019/11/15 00:00 [received] PHST- 2019/11/25 00:00 [revised] PHST- 2019/11/26 00:00 [accepted] PHST- 2019/12/11 06:00 [entrez] PHST- 2019/12/11 06:00 [pubmed] PHST- 2020/07/01 06:00 [medline] PHST- 2019/12/01 00:00 [pmc-release] AID - nu11122934 [pii] AID - nutrients-11-02934 [pii] AID - 10.3390/nu11122934 [doi] PST - epublish SO - Nutrients. 2019 Dec 3;11(12):2934. doi: 10.3390/nu11122934.