PMID- 31819355 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200929 IS - 1177-5467 (Print) IS - 1177-5483 (Electronic) IS - 1177-5467 (Linking) VI - 13 DP - 2019 TI - Main Complications of Photorefractive Keratectomy and their Management. PG - 2305-2315 LID - 10.2147/OPTH.S233125 [doi] AB - Photorefractive keratectomy (PRK) was the first surface ablation procedure introduced for the treatment of refractive errors and has been proven to be effective and safe. In some cases, however, the patient may not be totally satisfied with the final result and retreatment may be necessary. We performed a literature review to describe the main conditions that may arise following PRK that may require retreatment and new promising techniques to allow customized and effective treatments for patients. There is currently no gold standard for retreatment of residual refractive error after PRK. The surgeon must take into account the patient's history and type of problem when choosing the most appropriate technique. LASIK and PRK are the main options. Haze can be treated with good results with phototherapeutic keratectomy and mytomicin C. High order aberrations and decentration may be addressed with topographically-guided excimer photoablation or with wavefront-guided PRK. CI - (c) 2019 Spadea and Giovannetti. FAU - Spadea, Leopoldo AU - Spadea L AUID- ORCID: 0000-0002-1190-3956 AD - Eye Clinic, Policlinico Umberto 1, Department of Sensory Organs, "La Sapienza" University of Rome, Rome, Italy. FAU - Giovannetti, Francesca AU - Giovannetti F AUID- ORCID: 0000-0002-7661-6675 AD - Eye Clinic, Policlinico Umberto 1, Department of Sensory Organs, "La Sapienza" University of Rome, Rome, Italy. LA - eng PT - Journal Article PT - Review DEP - 20191127 PL - New Zealand TA - Clin Ophthalmol JT - Clinical ophthalmology (Auckland, N.Z.) JID - 101321512 PMC - PMC6885542 OTO - NOTNLM OT - HOA OT - corneal wound healing OT - decentration OT - enhancement OT - haze OT - photorefractive keratectomy OT - regression OT - topographically-guided excimer laser photoablation COIS- The authors report no conflicts of interest in this work. EDAT- 2019/12/11 06:00 MHDA- 2019/12/11 06:01 PMCR- 2019/11/27 CRDT- 2019/12/11 06:00 PHST- 2019/10/04 00:00 [received] PHST- 2019/11/06 00:00 [accepted] PHST- 2019/12/11 06:00 [entrez] PHST- 2019/12/11 06:00 [pubmed] PHST- 2019/12/11 06:01 [medline] PHST- 2019/11/27 00:00 [pmc-release] AID - 233125 [pii] AID - 10.2147/OPTH.S233125 [doi] PST - epublish SO - Clin Ophthalmol. 2019 Nov 27;13:2305-2315. doi: 10.2147/OPTH.S233125. eCollection 2019.