PMID- 31821993 OWN - NLM STAT- MEDLINE DCOM- 20210407 LR - 20210407 IS - 1543-3072 (Electronic) IS - 1056-6716 (Linking) VI - 29 IP - 7 DP - 2020 Sep 1 TI - Acute Muscular Responses to Practical Low-Load Blood Flow Restriction Exercise Versus Traditional Low-Load Blood Flow Restriction and High-/Low-Load Exercise. PG - 984-992 LID - jsr.2019-0217 [pii] LID - 10.1123/jsr.2019-0217 [doi] AB - CONTEXT: Blood flow restriction (BFR) increases muscle size and strength when combined with low loads, but various methods are used to produce this stimulus. It is unclear how using elastic knee wraps can impact acute muscular responses compared with using nylon cuffs, where the pressure can be standardized. OBJECTIVE: Investigate how elastic knee wraps compare with nylon cuffs and high-load (HL)/low-load (LL) resistance exercise. DESIGN: A randomized cross-over experimental design using 6 conditions combined with unilateral knee extension. SETTING: Human Performance Laboratory. PARTICIPANTS: A total of 9 healthy participants (males = 7 and females = 2) and had an average age of 22 (4) years. INTERVENTION: LL (30% of 1-repetition maximum [1-RM]), HL (70% 1-RM), BFR at 40% of arterial occlusion pressure (BFR-LOW), BFR at 80% of arterial occlusion pressure (BFR-HIGH), elastic knee wraps stretched by 2 in (PRACTICAL-LOW), and elastic knee wraps stretched to a new length equivalent to 85% of thigh circumference (PRACTICAL-HIGH). BFR and practical conditions used 30% 1-RM. MAIN OUTCOME MEASURES: Muscle thickness, maximum voluntary isometric contraction, and electromyography amplitude. Bayesian statistics evaluated differences in changes between conditions using the Bayes factor (BF10), and median and 95% credible intervals were reported from the posterior distribution. RESULTS: Total repetitions completed were greater for BFR-LOW versus PRACTICAL-HIGH (BF10 = 3.2, 48.6 vs 44 repetitions) and greater for PRACTICAL-LOW versus BFR-HIGH (BF10 = 717, 51.8 vs 36.3 repetitions). Greater decreases in changes in maximum voluntary isometric contraction were found in PRACTICAL-HIGH versus HL (BF10 = 1035, approximately 103 N) and LL (BF10 = 45, approximately 66 N). No differences in changes in muscle thickness were found between LL versus PRACTICAL-LOW/PRACTICAL-HIGH conditions (BF10 = 0.32). Greater changes in electromyography amplitude were also found for BFR-LOW versus PRACTICAL-HIGH condition (BF10 = 6.13, approximately 12%), but no differences were noted between the other BFR conditions. CONCLUSIONS: Overall, elastic knee wraps produce a more fatiguing stimulus than LL or HL conditions and might be used as an alternative to pneumatic cuffs that are traditionally used for BFR exercise. FAU - Thiebaud, Robert S AU - Thiebaud RS FAU - Abe, Takashi AU - Abe T FAU - Loenneke, Jeremy P AU - Loenneke JP FAU - Garcia, Tyler AU - Garcia T FAU - Shirazi, Yohan AU - Shirazi Y FAU - McArthur, Ross AU - McArthur R LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20191209 PL - United States TA - J Sport Rehabil JT - Journal of sport rehabilitation JID - 9206500 SB - IM MH - Adult MH - Cross-Over Studies MH - Electromyography MH - Female MH - Humans MH - Male MH - Muscle Strength/*physiology MH - Quadriceps Muscle/*blood supply/*physiology MH - Regional Blood Flow/*physiology MH - Resistance Training/*methods MH - Tourniquets MH - Young Adult OTO - NOTNLM OT - elastic knee wraps OT - muscle thickness OT - vascular occlusion EDAT- 2019/12/11 06:00 MHDA- 2021/04/10 06:00 CRDT- 2019/12/11 06:00 PHST- 2019/05/20 00:00 [received] PHST- 2019/09/19 00:00 [revised] PHST- 2019/10/15 00:00 [accepted] PHST- 2019/12/11 06:00 [pubmed] PHST- 2021/04/10 06:00 [medline] PHST- 2019/12/11 06:00 [entrez] AID - jsr.2019-0217 [pii] AID - 10.1123/jsr.2019-0217 [doi] PST - epublish SO - J Sport Rehabil. 2019 Dec 9;29(7):984-992. doi: 10.1123/jsr.2019-0217. Print 2020 Sep 1.