PMID- 31826576
OWN - NLM
STAT- MEDLINE
DCOM- 20191216
LR  - 20200108
IS  - 0376-2491 (Print)
IS  - 0376-2491 (Linking)
VI  - 99
IP  - 45
DP  - 2019 Dec 3
TI  - [Clinical characteristics of cardiomyopathies complicated with ventricular 
      thrombosis].
PG  - 3587-3591
LID - 10.3760/cma.j.issn.0376-2491.2019.45.011 [doi]
AB  - Objective: To summarize the clinical characteristics of cardiomyopathy 
      complicated with ventricular thrombosis. Methods: The clinical data of inpatients 
      suffered from cardiomyopathy complicated with ventricular thrombosis in Fuwai 
      Hospital between January 2015 and May 2019 were analyzed retrospectively. 
      Results: A total of 125 cases were reviewed, and 24.8% were female. Dilated 
      cardiomyopathy was the most common disease (62.4%), followed by arrhythmogenic 
      right ventricular cardiomyopathy (ARVC) (13.6%) and hypertrophic cardiomyopathy 
      (11.2%). There were 74.4% thrombosis in left ventricle, 12.8% in right ventricle 
      and 12.8% in biventricle. The proportions of right ventricle thrombosis were 
      higher in ARVC than in other cardiomyopathies (52.9% vs 6.5%, P<0.01). The 
      majority suffered from cardiac function New York Heart Association (NYHA) Class Ⅲ 
      (45.6%) and class Ⅳ (39.2%). The ratio of NYHA Class Ⅳ was higher in female 
      patients than in male ones (25.8% vs 10.6%, P<0.05). In lab detection, positive 
      results of D-Dimer and N terminal-pro B type natriuretic peptide (NT-proBNP) 
      accounted for 72.8% and 97.6%, respectively. There were 2.5% patients died in the 
      hospital or discharged because of the worsening of illness, the chances were 
      higher in female than male patients (9.7% vs 0, P<0.01). Among these patients, 
      one succumbed to massive ischemic stroke caused by ventricular thrombus 
      detachment under standard anticoagulation therapy. Conclusions: Dilated 
      cardiomyopathy is the most common cardiomyopathy complicated with ventricular 
      thrombosis. The most common location of thrombosis is left ventricle. Right 
      ventricle thrombosis is more common in ARVC. The majority suffer from moderate or 
      severe cardiac dysfunction. Higer proportion of female patients suffer from 
      anemia, severe condition and poor prognosis.
FAU - Hu, Z C
AU  - Hu ZC
AD  - Center of Arrhythmia, Fuwai Hospital, National Center for Cardiovascular 
      Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, 
      Beijing 100037, China.
FAU - Wu, L M
AU  - Wu LM
FAU - Liu, S Y
AU  - Liu SY
FAU - Shen, L S
AU  - Shen LS
FAU - Zhao, M H
AU  - Zhao MH
FAU - Liu, L M
AU  - Liu LM
FAU - Ding, L G
AU  - Ding LG
FAU - Zheng, L H
AU  - Zheng LH
FAU - Yao, Y
AU  - Yao Y
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhonghua Yi Xue Za Zhi
JT  - Zhonghua yi xue za zhi
JID - 7511141
SB  - IM
MH  - *Arrhythmogenic Right Ventricular Dysplasia
MH  - *Cardiomyopathies
MH  - *Cardiomyopathy, Dilated
MH  - Female
MH  - Humans
MH  - Male
MH  - Retrospective Studies
MH  - *Thrombosis
OTO - NOTNLM
OT  - Cardiomyopathy
OT  - Clinical features
OT  - Intracardiac thrombosis
EDAT- 2019/12/13 06:00
MHDA- 2019/12/18 06:00
CRDT- 2019/12/13 06:00
PHST- 2019/12/13 06:00 [entrez]
PHST- 2019/12/13 06:00 [pubmed]
PHST- 2019/12/18 06:00 [medline]
AID - 10.3760/cma.j.issn.0376-2491.2019.45.011 [doi]
PST - ppublish
SO  - Zhonghua Yi Xue Za Zhi. 2019 Dec 3;99(45):3587-3591. doi: 
      10.3760/cma.j.issn.0376-2491.2019.45.011.