PMID- 31827806 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220411 IS - 2052-1847 (Print) IS - 2052-1847 (Electronic) IS - 2052-1847 (Linking) VI - 11 DP - 2019 TI - The effects of two weeks high-intensity interval training on fasting glucose, glucose tolerance and insulin resistance in adolescent boys: a pilot study. PG - 29 LID - 10.1186/s13102-019-0141-9 [doi] LID - 29 AB - BACKGROUND: Current evidence of metabolic health benefits of high-intensity interval training (HIIT) are limited to longer training periods or conducted in overweight youth. This study assessed 1) fasting and postprandial insulin and glucose before and after 2 weeks of HIIT in healthy adolescent boys, and 2) the relationship between pre intervention health outcomes and the effects of the HIIT intervention. METHODS: Seven healthy boys (age:14.3 +/- 0.3 y, BMI: 21.6 +/- 2.6, 3 participants classified as overweight) completed 6 sessions of HIIT over 2 weeks. Insulin resistance (IR) and blood glucose and insulin responses to a Mixed Meal Tolerance Test (MMTT) were assessed before (PRE), 20 h and 70 h after (POST) the final HIIT session. RESULTS: Two weeks of HIIT had no effect on fasting plasma glucose, insulin or IR at 20 h and 70 h POST HIIT, nor insulin and glucose response to MMTT (all P > 0.05). There was a strong negative correlation between PRE training IR and change in IR after HIIT (r = - 0.96, P < 0.05). CONCLUSION: Two weeks of HIIT did not elicit improvements to fasting or postprandial glucose or insulin health outcomes in a group of adolescent boys. However the negative correlation between PRE IR and improvements after HIIT suggest that interventions of this type may be effective in adolescents with raised baseline IR. CI - (c) The Author(s). 2019. FAU - Cockcroft, Emma J AU - Cockcroft EJ AUID- ORCID: 0000-0003-3798-9492 AD - 1Children's Health and Exercise Research Centre, Sport and Health Sciences, College of Life and Environmental Sciences, University of Exeter, Exeter, EX1 2LU UK. ISNI: 0000 0004 1936 8024. GRID: grid.8391.3 AD - 2College of Medicine and Health, University of Exeter, Exeter, EX1 2LU UK. ISNI: 0000 0004 1936 8024. GRID: grid.8391.3 FAU - Bond, Bert AU - Bond B AD - 1Children's Health and Exercise Research Centre, Sport and Health Sciences, College of Life and Environmental Sciences, University of Exeter, Exeter, EX1 2LU UK. ISNI: 0000 0004 1936 8024. GRID: grid.8391.3 FAU - Williams, Craig A AU - Williams CA AD - 1Children's Health and Exercise Research Centre, Sport and Health Sciences, College of Life and Environmental Sciences, University of Exeter, Exeter, EX1 2LU UK. ISNI: 0000 0004 1936 8024. GRID: grid.8391.3 FAU - Harris, Sam AU - Harris S AD - 3Sport and Health Sciences, College of Life and Environmental Sciences, University of Exeter, Exeter, EX1 2LU UK. ISNI: 0000 0004 1936 8024. GRID: grid.8391.3 FAU - Jackman, Sarah R AU - Jackman SR AD - 3Sport and Health Sciences, College of Life and Environmental Sciences, University of Exeter, Exeter, EX1 2LU UK. ISNI: 0000 0004 1936 8024. GRID: grid.8391.3 FAU - Armstrong, Neil AU - Armstrong N AD - 1Children's Health and Exercise Research Centre, Sport and Health Sciences, College of Life and Environmental Sciences, University of Exeter, Exeter, EX1 2LU UK. ISNI: 0000 0004 1936 8024. GRID: grid.8391.3 FAU - Barker, Alan R AU - Barker AR AD - 1Children's Health and Exercise Research Centre, Sport and Health Sciences, College of Life and Environmental Sciences, University of Exeter, Exeter, EX1 2LU UK. ISNI: 0000 0004 1936 8024. GRID: grid.8391.3 LA - eng PT - Journal Article DEP - 20191209 PL - England TA - BMC Sports Sci Med Rehabil JT - BMC sports science, medicine & rehabilitation JID - 101605016 PMC - PMC6900855 OTO - NOTNLM OT - Aerobic fitness OT - Cardiometabolic health OT - Physical activity OT - Youth COIS- Competing interestsThe authors declare that they have no competing interests. EDAT- 2019/12/13 06:00 MHDA- 2019/12/13 06:01 PMCR- 2019/12/09 CRDT- 2019/12/13 06:00 PHST- 2019/05/23 00:00 [received] PHST- 2019/10/10 00:00 [accepted] PHST- 2019/12/13 06:00 [entrez] PHST- 2019/12/13 06:00 [pubmed] PHST- 2019/12/13 06:01 [medline] PHST- 2019/12/09 00:00 [pmc-release] AID - 141 [pii] AID - 10.1186/s13102-019-0141-9 [doi] PST - epublish SO - BMC Sports Sci Med Rehabil. 2019 Dec 9;11:29. doi: 10.1186/s13102-019-0141-9. eCollection 2019.