PMID- 31828742
OWN - NLM
STAT- MEDLINE
DCOM- 20200113
LR  - 20201220
IS  - 1833-3516 (Print)
IS  - 2209-1491 (Electronic)
IS  - 1833-3516 (Linking)
VI  - 49
IP  - 4
DP  - 2019 Dec 20
TI  - The myopic shift associated with hyperbaric oxygen administration is reduced when 
      using a mask delivery system compared to a hood - a randomised controlled trial.
PG  - 245-252
LID - 10.28920/dhm49.4.245-252 [doi]
AB  - INTRODUCTION: A temporary myopic shift is a well-recognized complication of 
      hyperbaric oxygen treatment (HBOT). Oxidation of proteins in the crystalline lens 
      is the likely cause. Direct exposure of the eye to hyperbaric oxygen may 
      exacerbate the effect. Our aim was to measure the magnitude of the myopic shift 
      over a course of HBOT when using two different methods of oxygen delivery. 
      METHODS: We conducted a randomised trial of oxygen delivery via hood versus 
      oronasal mask during a course of 20 and 30 HBOT sessions. Subjective refraction 
      was performed at baseline and after 20 and 30 sessions. We repeated these 
      measurements at four and 12 weeks after completion of the course in those 
      available for assessment. RESULTS: We enrolled 120 patients (mean age 57.6 (SD 
      11.2) years; 81% male). The myopic shift was significantly greater after both 20 
      and 30 sessions in those patients using the hood. At 20 treatments: refractory 
      change was -0.92 D with hood versus -0.52 D with mask, difference 0.40 D (95% CI 
      0.22 to 0.57, P < 0.0001); at 30 treatments: -1.25 D with hood versus -0.63 with 
      mask, difference 0.62 D (95% CI 0.39 to 0.84, P < 0.0001). Recovery was slower 
      and less complete in the hood group at both four and 12 weeks. CONCLUSIONS: 
      Myopic shift is common following HBOT and more pronounced using a hood system 
      than an oronasal mask. Recovery may be slower and less complete using a hood. Our 
      data support the use of an oronasal mask in an air environment when possible.
CI  - Copyright: This article is the copyright of the authors who grant Diving and 
      Hyperbaric Medicine a non-exclusive licence to publish the article in electronic 
      and other forms.
FAU - Bennett, Michael H
AU  - Bennett MH
AD  - Prince of Wales Clinical School, University of New South Wales, Sydney, 
      Australia.
AD  - Department of Diving and Hyperbaric Medicine, Prince of Wales Hospital, Sydney, 
      Australia.
AD  - Corresponding author: Prince of Wales Clinical School and Academic Director, 
      Wales Anaesthesia, Ground Floor, East Wing Edmund Blackett Building, Prince of 
      Wales Hospital, Barker Street, Randwick, NSW 2031, Australia, 
      m.bennett@unsw.edu.au.
FAU - Hui, Cheng Fb
AU  - Hui CF
AD  - Prince of Wales Clinical School, University of New South Wales, Sydney, 
      Australia.
AD  - Department of Diving and Hyperbaric Medicine, Prince of Wales Hospital, Sydney, 
      Australia.
FAU - See, Hooi G
AU  - See HG
AD  - Division of Anaesthesiology and Perioperative Medicine, Singapore General 
      Hospital, Singapore.
FAU - Au-Yeung, Kwan L
AU  - Au-Yeung KL
AD  - Department of Emergency Medicine, Princess Elizabeth Hospital, Hong Kong.
FAU - Tan, Christopher
AU  - Tan C
AD  - Department of Anaesthesia, The Wollongong Hospital, Wollongong, Australia.
FAU - Watson, Stephanie
AU  - Watson S
AD  - Prince of Wales Clinical School, University of New South Wales, Sydney, 
      Australia.
AD  - Save Sight Institute, Discipline of Ophthalmology, The University of Sydney, 
      Sydney, Australia.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - Australia
TA  - Diving Hyperb Med
JT  - Diving and hyperbaric medicine
JID - 101282742
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Female
MH  - Humans
MH  - *Hyperbaric Oxygenation/adverse effects/instrumentation/methods
MH  - Male
MH  - Masks
MH  - Middle Aged
MH  - *Myopia/etiology
MH  - Oxygen/administration & dosage
PMC - PMC7039782
OTO - NOTNLM
OT  - Hyperbaric oxygen
OT  - Myopia
OT  - Ophthalmology
OT  - Side effects
OT  - Vision
EDAT- 2019/12/13 06:00
MHDA- 2020/01/14 06:00
PMCR- 2020/12/20
CRDT- 2019/12/13 06:00
PHST- 2019/04/10 00:00 [received]
PHST- 2019/05/17 00:00 [accepted]
PHST- 2019/12/13 06:00 [entrez]
PHST- 2019/12/13 06:00 [pubmed]
PHST- 2020/01/14 06:00 [medline]
PHST- 2020/12/20 00:00 [pmc-release]
AID - 10.28920/dhm49.4.245-252 [doi]
PST - ppublish
SO  - Diving Hyperb Med. 2019 Dec 20;49(4):245-252. doi: 10.28920/dhm49.4.245-252.