PMID- 31832059
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1660-3796 (Print)
IS  - 1660-3818 (Electronic)
IS  - 1660-3796 (Linking)
VI  - 46
IP  - 5
DP  - 2019 Oct
TI  - Impact, Screening, and Therapy of HLA Antibodies in Patients before and after 
      Lung Transplantation.
PG  - 337-347
LID - 10.1159/000502124 [doi]
AB  - Since almost 30 years, lung transplantation is a considerable therapeutic option 
      in patients suffering from end-stage lung disease. Up to now, the impact of 
      donor-specific antibodies directed against donor HLA (human leukocyte antigen) 
      before and after transplantation is still a matter of debate. As 
      histocompatibility testing is not required for each patient according to the 
      current national guidelines and Eurotransplant recommendations for lung 
      transplantation, each transplantation unit has to establish a local protocol 
      together with the tissue typing laboratory how to implement an immunological risk 
      assessment strategy for their patients while enabling access to transplantation. 
      Desensitization regimens might help in case of highly alloimmunized patients 
      waiting for urgent transplantation.
CI  - Copyright (c) 2019 by S. Karger AG, Basel.
FAU - Dick, Andrea
AU  - Dick A
AD  - Division of Transfusion Medicine, Cellular Therapeutics, and Hemostaseology, 
      University Clinic LMU Munich, Munich, Germany.
FAU - Humpe, Andreas
AU  - Humpe A
AD  - Division of Transfusion Medicine, Cellular Therapeutics, and Hemostaseology, 
      University Clinic LMU Munich, Munich, Germany.
FAU - Kauke, Teresa
AU  - Kauke T
AD  - Division of Transfusion Medicine, Cellular Therapeutics, and Hemostaseology, 
      University Clinic LMU Munich, Munich, Germany.
AD  - Division of Thoracic Surgery, University Clinic LMU Munich, Munich, Germany.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20190820
PL  - Switzerland
TA  - Transfus Med Hemother
JT  - Transfusion medicine and hemotherapy : offizielles Organ der Deutschen 
      Gesellschaft fur Transfusionsmedizin und Immunhamatologie
JID - 101176417
PMC - PMC6876583
OTO - NOTNLM
OT  - Alloimmunization
OT  - Antibody-mediated rejection
OT  - HLA antibodies
OT  - Lung transplantation
COIS- There are no conflicts of interest. The authors have no funding to disclose.
EDAT- 2019/12/14 06:00
MHDA- 2019/12/14 06:01
PMCR- 2019/08/20
CRDT- 2019/12/14 06:00
PHST- 2019/05/03 00:00 [received]
PHST- 2019/07/13 00:00 [accepted]
PHST- 2019/12/14 06:00 [entrez]
PHST- 2019/12/14 06:00 [pubmed]
PHST- 2019/12/14 06:01 [medline]
PHST- 2019/08/20 00:00 [pmc-release]
AID - tmh-0046-0337 [pii]
AID - 10.1159/000502124 [doi]
PST - ppublish
SO  - Transfus Med Hemother. 2019 Oct;46(5):337-347. doi: 10.1159/000502124. Epub 2019 
      Aug 20.