PMID- 31834942
OWN - NLM
STAT- MEDLINE
DCOM- 20200826
LR  - 20200826
IS  - 1439-0531 (Electronic)
IS  - 0936-6768 (Linking)
VI  - 55
IP  - 2
DP  - 2020 Feb
TI  - Premature centromere division (PCD) identified in a hucul mare with reproductive 
      difficulties.
PG  - 248-251
LID - 10.1111/rda.13605 [doi]
AB  - A hucul mare with reproductive abnormalities was examined during karyotype 
      analysis. The karyotype was analysed based on evaluation of 860 metaphase plates 
      in chromosome preparations. The use of fluorescence in situ hybridization (FISH) 
      with an X chromosome painting probe showed premature X chromosome separation in 
      9.5% cases of examined chromosome spreads. In this report, we present the first 
      identify premature centromere division (PCD) as a possible cause of abnormal X 
      chromosome morphology in horses and as a probable cause of reproductive 
      difficulties.
CI  - (c) 2019 Blackwell Verlag GmbH.
FAU - Witarski, Wojciech
AU  - Witarski W
AUID- ORCID: 0000-0001-8957-8623
AD  - Department of Animal Genetics, National Institute of Animal Production, Balice, 
      Poland.
FAU - Kij, Barbara
AU  - Kij B
AD  - Department of Animal Reproduction, Anatomy and Genomics, University of 
      Agriculture in Krakow, Krakow, Poland.
FAU - Nowak, Agnieszka
AU  - Nowak A
AD  - Department of Animal Reproduction, Anatomy and Genomics, University of 
      Agriculture in Krakow, Krakow, Poland.
FAU - Bugno-Poniewierska, Monika
AU  - Bugno-Poniewierska M
AUID- ORCID: 0000-0001-7537-6641
AD  - Department of Animal Reproduction, Anatomy and Genomics, University of 
      Agriculture in Krakow, Krakow, Poland.
LA  - eng
GR  - NCBiR:BIOSTRATEG2/297267/14/NCBR/2016/National Centre for Research and 
      Development,/
PT  - Case Reports
PT  - Journal Article
DEP - 20191226
PL  - Germany
TA  - Reprod Domest Anim
JT  - Reproduction in domestic animals = Zuchthygiene
JID - 9015668
SB  - IM
MH  - Animals
MH  - Centromere/*genetics
MH  - Female
MH  - Horses/*genetics
MH  - Infertility, Female/genetics/*veterinary
MH  - Sex Chromosome Aberrations/*veterinary
MH  - X Chromosome/genetics
OTO - NOTNLM
OT  - FISH
OT  - X chromosome
OT  - horses
OT  - painting probe
OT  - premature centromere division
EDAT- 2019/12/14 06:00
MHDA- 2020/08/28 06:00
CRDT- 2019/12/14 06:00
PHST- 2019/10/29 00:00 [received]
PHST- 2019/12/08 00:00 [accepted]
PHST- 2019/12/14 06:00 [pubmed]
PHST- 2020/08/28 06:00 [medline]
PHST- 2019/12/14 06:00 [entrez]
AID - 10.1111/rda.13605 [doi]
PST - ppublish
SO  - Reprod Domest Anim. 2020 Feb;55(2):248-251. doi: 10.1111/rda.13605. Epub 2019 Dec 
      26.