PMID- 31839148
OWN - NLM
STAT- MEDLINE
DCOM- 20200624
LR  - 20200711
IS  - 1879-1913 (Electronic)
IS  - 0002-9149 (Linking)
VI  - 125
IP  - 4
DP  - 2020 Feb 15
TI  - Computed Tomography Features of Cuspal Thrombosis and Subvalvular Tissue Ingrowth 
      after Transcatheter Aortic Valve Implantation.
PG  - 597-606
LID - S0002-9149(19)31309-8 [pii]
LID - 10.1016/j.amjcard.2019.11.015 [doi]
AB  - Post-transcatheter aortic valve implantation (TAVI) computed tomography (CT) 
      findings have not been fully elucidated, except hypoattenuating leaflet 
      thickening (HALT). The objective of this study was to describe cardiac CT 
      findings after TAVI, and investigate factors associated with HALT. This 
      retrospective study included patients who underwent TAVI and post-TAVI cardiac CT 
      scans. On CT, abnormal findings such as hypoattenuating subvalvular thickening 
      (HAST), thrombus within the sinus of Valsalva, HALT, and leaflet motion 
      limitation were thoroughly reviewed. Clinical and CT findings were compared 
      between patients with HALT and those without HALT. Logistic regression analysis 
      was performed to determine factors associated with HALT. A total of 138 patients 
      (64 male, mean 78.5 +/- 5.2 years of age) with post-TAVI CT scans were included. 
      The median duration from TAVI to CT was 17.5 days (interquartile range, 3 to 
      390.8 days). HAST and thrombus within the sinus of Valsalva were detected in 32 
      (23%) and 5 (4%) patients, respectively. HALT and leaflet motion limitations were 
      found in 25 (18%) and 20 (14%) of patients, respectively. Pannus was diagnosed in 
      2 patients. TAVI device implant duration (odds ratio [OR], 1.5; p = 0.01), 
      hypertension (OR, 0.2; p = 0.03), and HAST (OR, 4.9; p = 0.003) were associated 
      with HALT. Implant durations were longer in patients with HAST, HALT, or leaflet 
      motion limitation (p < 0.05, for all). In conclusion, HAST, HALT, thrombus within 
      the sinus of Valsalva, and leaflet motion limitation are not uncommon after TAVI. 
      Implant duration, hypertension, and HAST are associated with HALT.
CI  - Copyright (c) 2019 Elsevier Inc. All rights reserved.
FAU - Koo, Hyun Jung
AU  - Koo HJ
AD  - Department of Radiology and Research Institute of Radiology, Cardiac Imaging 
      Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 
      South Korea.
FAU - Choe, Jooae
AU  - Choe J
AD  - Department of Radiology and Research Institute of Radiology, Cardiac Imaging 
      Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 
      South Korea.
FAU - Kang, Do-Yoon
AU  - Kang DY
AD  - Division of Cardiology, Asan Medical Center, University of Ulsan College of 
      Medicine, Seoul, South Korea.
FAU - Ko, Euihong
AU  - Ko E
AD  - Division of Cardiology, Asan Medical Center, University of Ulsan College of 
      Medicine, Seoul, South Korea.
FAU - Ahn, Jung-Min
AU  - Ahn JM
AD  - Division of Cardiology, Asan Medical Center, University of Ulsan College of 
      Medicine, Seoul, South Korea.
FAU - Park, Duk-Woo
AU  - Park DW
AD  - Division of Cardiology, Asan Medical Center, University of Ulsan College of 
      Medicine, Seoul, South Korea.
FAU - Park, Seung-Jung
AU  - Park SJ
AD  - Division of Cardiology, Asan Medical Center, University of Ulsan College of 
      Medicine, Seoul, South Korea.
FAU - Kim, Ho Jin
AU  - Kim HJ
AD  - Division of Thoracic and Cardiovascular Surgery, Asan Medical Center, University 
      of Ulsan College of Medicine, Seoul, South Korea.
FAU - Kim, Joon Bum
AU  - Kim JB
AD  - Division of Thoracic and Cardiovascular Surgery, Asan Medical Center, University 
      of Ulsan College of Medicine, Seoul, South Korea.
FAU - Choo, Suk Jung
AU  - Choo SJ
AD  - Division of Thoracic and Cardiovascular Surgery, Asan Medical Center, University 
      of Ulsan College of Medicine, Seoul, South Korea.
FAU - Kang, Joon-Won
AU  - Kang JW
AD  - Department of Radiology and Research Institute of Radiology, Cardiac Imaging 
      Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 
      South Korea.
FAU - Yang, Dong Hyun
AU  - Yang DH
AD  - Department of Radiology and Research Institute of Radiology, Cardiac Imaging 
      Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 
      South Korea. Electronic address: donghyun.yang@gmail.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20191121
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Aortic Valve/*diagnostic imaging/*pathology
MH  - Echocardiography
MH  - Female
MH  - Humans
MH  - Male
MH  - *Multidetector Computed Tomography
MH  - Postoperative Complications/*diagnostic imaging
MH  - Retrospective Studies
MH  - Thrombosis/*diagnostic imaging
MH  - *Transcatheter Aortic Valve Replacement
EDAT- 2019/12/17 06:00
MHDA- 2020/06/25 06:00
CRDT- 2019/12/17 06:00
PHST- 2019/09/11 00:00 [received]
PHST- 2019/10/30 00:00 [revised]
PHST- 2019/11/01 00:00 [accepted]
PHST- 2019/12/17 06:00 [pubmed]
PHST- 2020/06/25 06:00 [medline]
PHST- 2019/12/17 06:00 [entrez]
AID - S0002-9149(19)31309-8 [pii]
AID - 10.1016/j.amjcard.2019.11.015 [doi]
PST - ppublish
SO  - Am J Cardiol. 2020 Feb 15;125(4):597-606. doi: 10.1016/j.amjcard.2019.11.015. 
      Epub 2019 Nov 21.