PMID- 31839271
OWN - NLM
STAT- MEDLINE
DCOM- 20201117
LR  - 20201117
IS  - 1768-3122 (Electronic)
IS  - 0248-8663 (Linking)
VI  - 41
IP  - 1
DP  - 2020 Jan
TI  - [ANCA and anti-MBG double-positive vasculitis: An update on the clinical and 
      therapeutic specificities and comparison with the two eponymous vasculitis].
PG  - 21-26
LID - S0248-8663(19)31114-2 [pii]
LID - 10.1016/j.revmed.2019.10.334 [doi]
AB  - Double-positive vasculitis with anti-polynuclear cytoplasm (ANCA) and 
      anti-glomerular basement membrane (GBM) antibodies is a rare entity of systemic 
      vasculitis defined by the presence of ANCA and anti-GBM antibodies. The gradual 
      accumulation of clinical and therapeutic data shows the usefulness of identifying 
      and differentiating this entity from the two vasculitis respectively associated 
      with the isolated presence of each of these two antibodies. Indeed, the 
      double-positive ANCA and anti-GBM vasculitis appears to associate the 
      characteristics of the demography and the extra-renal and pulmonary involvement 
      of the ANCA-associated vasculitis on the one hand, and of the histological type 
      and severe renal prognosis of the anti-MBG vasculitis on the other hand, with the 
      renal involvement which is the only involvement consistently observed in 
      double-positive vasculitis. The aim of this focus is to describe the 
      epidemiological, clinico-biological, histological and prognostic characteristics 
      of this entity, in light of recent literature and ongoing therapeutic changes in 
      the two eponymous vasculitis.
CI  - Copyright (c) 2019 Societe Nationale Francaise de Medecine Interne (SNFMI). 
      Published by Elsevier Masson SAS. All rights reserved.
FAU - Philip, R
AU  - Philip R
AD  - Service de medecine interne et immunologie clinique, UNICAEN, Normandie 
      Universite, CHU de Caen Normandie, 14000 Caen, France.
FAU - Dumont, A
AU  - Dumont A
AD  - Service de medecine interne et immunologie clinique, UNICAEN, Normandie 
      Universite, CHU de Caen Normandie, 14000 Caen, France.
FAU - Le Mauff, B
AU  - Le Mauff B
AD  - Laboratoire d'Immunologie, UNICAEN, Normandie Universite, CHU de Caen Normandie, 
      14000 Caen, France.
FAU - Martinet, M
AU  - Martinet M
AD  - Laboratoire d'Immunologie, UNICAEN, Normandie Universite, CHU de Caen Normandie, 
      14000 Caen, France.
FAU - Martin Silva, N
AU  - Martin Silva N
AD  - Service de medecine interne et immunologie clinique, UNICAEN, Normandie 
      Universite, CHU de Caen Normandie, 14000 Caen, France.
FAU - de Boysson, H
AU  - de Boysson H
AD  - Service de medecine interne et immunologie clinique, UNICAEN, Normandie 
      Universite, CHU de Caen Normandie, 14000 Caen, France.
FAU - Lobbedez, T
AU  - Lobbedez T
AD  - Service de nephrologie, UNICAEN, Normandie Universite, CHU de Caen Normandie, 
      14000 Caen, France.
FAU - Aouba, A
AU  - Aouba A
AD  - Service de medecine interne et immunologie clinique, UNICAEN, Normandie 
      Universite, CHU de Caen Normandie, 14000 Caen, France. Electronic address: 
      aouba-a@chu-caen.fr.
FAU - Deshayes, S
AU  - Deshayes S
AD  - Service de medecine interne et immunologie clinique, UNICAEN, Normandie 
      Universite, CHU de Caen Normandie, 14000 Caen, France.
LA  - fre
PT  - Journal Article
PT  - Review
TT  - Vascularites double-positives ANCA et anti-MBG : mise au point sur les 
      specificites cliniques et therapeutiques et comparaison aux deux vascularites 
      eponymes.
DEP - 20191212
PL  - France
TA  - Rev Med Interne
JT  - La Revue de medecine interne
JID - 8101383
RN  - 0 (Antibodies, Antineutrophil Cytoplasmic)
RN  - 0 (Autoantibodies)
RN  - 0 (Glucocorticoids)
RN  - 0 (Immunosuppressive Agents)
RN  - 0 (antiglomerular basement membrane antibody)
SB  - IM
MH  - Anti-Glomerular Basement Membrane Disease/*diagnosis/*therapy
MH  - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/*diagnosis/*therapy
MH  - Antibodies, Antineutrophil Cytoplasmic/*blood
MH  - Autoantibodies/*blood
MH  - Glucocorticoids/therapeutic use
MH  - Humans
MH  - Immunosuppressive Agents/therapeutic use
MH  - Plasma Exchange
MH  - Prognosis
OTO - NOTNLM
OT  - ANCA-associated vasculitis
OT  - Anti-GBM vasculitis
OT  - Double-positive vasculitis
OT  - Goodpasture's syndrome
OT  - Syndrome de Goodpasture
OT  - Vascularites double-positives
OT  - Vascularites a ANCA
OT  - Vascularites a anticorps anti-MBG
EDAT- 2019/12/17 06:00
MHDA- 2020/11/18 06:00
CRDT- 2019/12/17 06:00
PHST- 2019/03/09 00:00 [received]
PHST- 2019/07/21 00:00 [revised]
PHST- 2019/10/21 00:00 [accepted]
PHST- 2019/12/17 06:00 [pubmed]
PHST- 2020/11/18 06:00 [medline]
PHST- 2019/12/17 06:00 [entrez]
AID - S0248-8663(19)31114-2 [pii]
AID - 10.1016/j.revmed.2019.10.334 [doi]
PST - ppublish
SO  - Rev Med Interne. 2020 Jan;41(1):21-26. doi: 10.1016/j.revmed.2019.10.334. Epub 
      2019 Dec 12.