PMID- 31843986
OWN - NLM
STAT- MEDLINE
DCOM- 20210402
LR  - 20210402
IS  - 1948-2124 (Electronic)
IS  - 1079-7440 (Linking)
VI  - 74
IP  - 3
DP  - 2020 May-Jun
TI  - Practical Applications of Biofluorescent Particle Counting in Environmental 
      Monitoring Investigations.
PG  - 318-323
LID - 10.5731/pdajpst.2019.009969 [doi]
AB  - Investigations into environmental monitoring (EM) excursions can be prolonged and 
      do not always result in clear root causes or corrective and preventative actions. 
      This article outlines how biofluorescent particle counting (BFPC) can be used in 
      investigations to eliminate the inherent delays of culture-based methods. The 
      application for investigations supplements routine EM, acting as a risk-reduction 
      tool enabling real-time detection of viable microorganisms in air samples and 
      supporting root cause analysis and remedial actions. The article includes 
      guidance on how to use the technology, a real case study involving a mold 
      excursion, and examples of business benefits achieved by various companies.
CI  - (c) PDA, Inc. 2020.
FAU - Prasad, Aditya
AU  - Prasad A
AD  - AstraZeneca, Philadelphia, PA, USA.
FAU - Milling, Annett
AU  - Milling A
AD  - CSL Behring, Bradley, IL, USA.
FAU - Hauschild, James
AU  - Hauschild J
AD  - Johnson & Johnson, East Raritan, NJ, USA.
FAU - Ruh, Ann-Caroline
AU  - Ruh AC
AD  - GSK Vaccines, Wavre, Belgium.
FAU - Horsch, Jeff
AU  - Horsch J
AD  - Bristol-Myers Squibb, New Brunswick, NJ, USA.
FAU - Weber, Jeffrey
AU  - Weber J
AD  - Pfizer, Kalamazoo, MI, USA.
FAU - Yan, Lisa
AU  - Yan L
AD  - Shire, Los Angeles, CA, USA.
FAU - Plourde, Lucile
AU  - Plourde L
AD  - Sanofi Pasteur, Marcy-l'Etoile, France.
FAU - Claassen, Marja
AU  - Claassen M
AD  - Merck, Sharp & Dohme, Oss, The Netherlands.
FAU - Villari, Philip
AU  - Villari P
AD  - Merck, West Point, PA, USA.
FAU - IJzerman-Boon, Pieta
AU  - IJzerman-Boon P
AD  - Merck, Sharp & Dohme, Oss, The Netherlands.
FAU - Forng, Ren-Yo
AU  - Forng RY
AD  - Amgen, Thousand Oaks, CA, USA.
FAU - Henry, Robert Bo
AU  - Henry RB
AD  - Catalent Biologics, Bloomington, IN, USA.
FAU - Portmann, Roland
AU  - Portmann R
AD  - CSL Behring, Bern, Switzerland.
FAU - Shereefa, Shebeer
AU  - Shereefa S
AD  - Abbvie, North Chicago, IL, USA; and.
FAU - Urwyler, Simon
AU  - Urwyler S
AD  - CSL Behring, Bern, Switzerland.
FAU - Dassu, Dawood
AU  - Dassu D
AD  - BioPhorum, Sheffield, UK dawood@biophorum.com.
LA  - eng
PT  - Journal Article
DEP - 20191216
PL  - United States
TA  - PDA J Pharm Sci Technol
JT  - PDA journal of pharmaceutical science and technology
JID - 9439538
RN  - 0 (Fluorescent Dyes)
SB  - IM
MH  - Air Filters/*standards
MH  - Air Microbiology/*standards
MH  - Drug Contamination/*prevention & control
MH  - Environmental Monitoring/methods/*standards
MH  - Fluorescent Dyes/*analysis
MH  - Humans
MH  - *Particle Size
EDAT- 2019/12/18 06:00
MHDA- 2021/04/07 06:00
CRDT- 2019/12/18 06:00
PHST- 2019/12/18 06:00 [pubmed]
PHST- 2021/04/07 06:00 [medline]
PHST- 2019/12/18 06:00 [entrez]
AID - pdajpst.2019.009969 [pii]
AID - 10.5731/pdajpst.2019.009969 [doi]
PST - ppublish
SO  - PDA J Pharm Sci Technol. 2020 May-Jun;74(3):318-323. doi: 
      10.5731/pdajpst.2019.009969. Epub 2019 Dec 16.