PMID- 31848736
OWN - NLM
STAT- MEDLINE
DCOM- 20210210
LR  - 20211006
IS  - 1437-160X (Electronic)
IS  - 0172-8172 (Print)
IS  - 0172-8172 (Linking)
VI  - 40
IP  - 3
DP  - 2020 Mar
TI  - Physical activity and sedentary behaviour and their associations with clinical 
      measures in axial spondyloarthritis.
PG  - 375-381
LID - 10.1007/s00296-019-04494-3 [doi]
AB  - Engaging in physical activity (PA) is a key aspect in the management of axial 
      spondyloarthritis (axial SpA), however, its relationship with clinical measures 
      is unknown. Previous research has mainly focused on subjective methods of 
      measuring PA and sedentary behaviour (SB). The aim of this study was to explore 
      the associations between objectively measured PA and SB with clinical measures in 
      people with established axial SpA. Fifty participants were recruited from 
      secondary-care rheumatology outpatient services in Glasgow, UK. Clinical measures 
      collected included; Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), 
      Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis 
      Metrology Index (BASMI), Ankylosing Spondylitis Quality of Life (ASQOL) and the 
      Six Minute Walk Test (6MWT). PA and SB were measured using the activPAL3 
      tri-axial accelerometer. Data from forty-five participants were included (23 
      males, average age 49 +/- 12 years). Participants accumulated an average of 
      93.2 +/- 41.5 min/day walking with an average of 7200 +/- 3397 steps/day. The 
      majority of the day (65%) was spent sitting, accumulated in prolonged bouts. 
      Walking time and steps taken/day were associated with better BASFI (r = - 0.395, 
      p = 0.007 and r = - 0.404, p = 0.006), ASQOL (r = - 0.375, p = 0.011 and 
      r = - 0.361, p = 0.015) and 6MWT (r = 0.396, p = 0.007 and r = 0.421, p = 0.004); 
      while longer walking events were associated with better BASMI (rho = - 0.352, 
      p = 0.018), BASFI (rho = - 0.316, p = 0.034) and 6MWT (rho = 0.404, p = 0.006). 
      SB was associated with worse ASQOL (r = 0.380, p = 0.010) and 6MWT (6MWT, 
      r = - 0.357, p = 0.016). In people with axial SpA PA is associated with better 
      function, exercise capacity and spinal mobility, while SB is associated with 
      lower exercise capacity and poor quality of life. These findings support the 
      promotion of PA and reduction of SB in people with axial SpA.
FAU - Coulter, Elaine H
AU  - Coulter EH
AUID- ORCID: 0000-0001-5246-0576
AD  - School of Health and Life Sciences, Glasgow Caledonian University, Cowcaddens 
      Road, Glasgow, UK.
FAU - McDonald, Marie Therese
AU  - McDonald MT
AUID- ORCID: 0000-0003-4950-5854
AD  - School of Health and Life Sciences, Glasgow Caledonian University, Cowcaddens 
      Road, Glasgow, UK. MarieTherese.McDonald@gcu.ac.uk.
AD  - Rheumatology Service, Queen Elizabeth University Hospital, NHS Greater Glasgow 
      and Clyde, Glasgow, UK. MarieTherese.McDonald@gcu.ac.uk.
AD  - Institute of Infection, Immunity and Inflammation, University of Glasgow, Sir 
      Graeme Davies Building, University Place, Glasgow, UK. 
      MarieTherese.McDonald@gcu.ac.uk.
FAU - Cameron, Sara
AU  - Cameron S
AD  - School of Medicine, Dentistry and Nursing, University of Glasgow, Oakfield 
      Avenue, Glasgow, UK.
FAU - Siebert, Stefan
AU  - Siebert S
AUID- ORCID: 0000-0002-1802-7311
AD  - Institute of Infection, Immunity and Inflammation, University of Glasgow, Sir 
      Graeme Davies Building, University Place, Glasgow, UK.
FAU - Paul, Lorna
AU  - Paul L
AUID- ORCID: 0000-0003-2869-0309
AD  - School of Health and Life Sciences, Glasgow Caledonian University, Cowcaddens 
      Road, Glasgow, UK.
LA  - eng
GR  - 20874/VAC_/Versus Arthritis/United Kingdom
PT  - Journal Article
DEP - 20191217
PL  - Germany
TA  - Rheumatol Int
JT  - Rheumatology international
JID - 8206885
SB  - IM
MH  - Adult
MH  - Exercise/*physiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Quality of Life
MH  - *Sedentary Behavior
MH  - Severity of Illness Index
MH  - Spondylarthritis/*diagnosis/physiopathology
MH  - Surveys and Questionnaires
PMC - PMC7002460
OTO - NOTNLM
OT  - Axial spondyloarthritis
OT  - Physical activity
OT  - Rheumatology
OT  - Sedentary behaviour
COIS- Dr Coulter, Ms McDonald, Dr Siebert and Professor Paul received a research grant 
      from Versus Arthritis (formally Arthritis Research UK) during the conduct of the 
      study. Ms Cameron declares no conflicts of interest.
EDAT- 2019/12/19 06:00
MHDA- 2021/02/11 06:00
PMCR- 2019/12/17
CRDT- 2019/12/19 06:00
PHST- 2019/09/10 00:00 [received]
PHST- 2019/12/09 00:00 [accepted]
PHST- 2019/12/19 06:00 [pubmed]
PHST- 2021/02/11 06:00 [medline]
PHST- 2019/12/19 06:00 [entrez]
PHST- 2019/12/17 00:00 [pmc-release]
AID - 10.1007/s00296-019-04494-3 [pii]
AID - 4494 [pii]
AID - 10.1007/s00296-019-04494-3 [doi]
PST - ppublish
SO  - Rheumatol Int. 2020 Mar;40(3):375-381. doi: 10.1007/s00296-019-04494-3. Epub 2019 
      Dec 17.