PMID- 31849537
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220411
IS  - 1179-1373 (Print)
IS  - 1179-1373 (Electronic)
IS  - 1179-1373 (Linking)
VI  - 11
DP  - 2019
TI  - Mother to Child Transmission of HIV and Associated Factors Among HIV Exposed 
      Infants at Public Health Facilities, Dessie Town, Ethiopia.
PG  - 343-350
LID - 10.2147/HIV.S221409 [doi]
AB  - BACKGROUND: Vertical transmission of Human Immunodeficiency Virus (HIV) is the 
      primary route of infection among children. Ethiopia is among the top ten 
      countries in the world with the highest burden of HIV infections among children. 
      Therefore we aimed to assess mother to child transmission (MTCT) of HIV and 
      associated factors among HIV exposed infants (HEIs). METHODS: A cross-sectional 
      study was conducted using retrospective data collected from HEIs paired with 
      their mothers who had received the services in prevention of mother to child 
      transmission (PMTCT) programs from January 2014 to December 2017 in public health 
      facilities in Dessie town. Data of a total of 313 HEIs paired with their mothers 
      were obtained by using semi-structured data extraction proforma from their 
      medical records. The data were processed in Epi-info version 7.1.2.0 and analyzed 
      using SPSS version 22. Crude and adjusted odds ratios with their 95% confidence 
      intervals and p-value were used to identify significant factors. RESULTS: The 
      prevalence of HIV among exposed infants was 3.8%. Absence of maternal antenatal 
      care visit (AOR = 4.6, 95% CI: 1.17-17.99), home delivery (AOR = 4.2, 95% CI: 
      1.04 -16.76), absence of antiretroviral intervention to the mother (AOR= 5.7, 95% 
      CI: 1.10-29.36), and failure to initiate nevirapine prophylaxis for the infant 
      (AOR = 5.3, 95% CI: 1.11 -25.44) were significant factors of MTCT of HIV. 
      CONCLUSION: Prevalence of MTCT of HIV was low (3.8%) in Dessie town public health 
      facilities. Having ANC visit, delivery at health facility, maternal ARV drug 
      intake, and infant ARV prophylaxis were the significant protective factors 
      against MTCT of HIV. Promoting ANC service utilization among pregnant women and 
      providing counseling as well as setting up linkage with PMTCT and giving ARV 
      intervention to all HIV positive pregnant women and timely initiation of NVP 
      prophylaxis to all HEIs should be recommended by the minister of health and 
      health facilities.
CI  - (c) 2019 Yitayew et al.
FAU - Yitayew, Yibeltal Asmamaw
AU  - Yitayew YA
AD  - Department of Nursing, College of Medicine and Health Sciences, Wollo University, 
      Dessie, Ethiopia.
FAU - Bekele, Daniel Mengistu
AU  - Bekele DM
AUID- ORCID: 0000-0003-3570-1117
AD  - School of Nursing and Midwifery, College of Health Science, Addis Ababa 
      University, Addis Ababa, Ethiopia.
FAU - Demissie, Birhanu Wondimeneh
AU  - Demissie BW
AUID- ORCID: 0000-0003-4019-6522
AD  - Department of Nursing, College of Medicine and Health Sciences, Wolaita Sodo 
      University, Sodo, Ethiopia.
FAU - Menji, Zeleke Argaw
AU  - Menji ZA
AD  - School of Nursing and Midwifery, College of Health Science, Addis Ababa 
      University, Addis Ababa, Ethiopia.
LA  - eng
PT  - Journal Article
DEP - 20191212
PL  - New Zealand
TA  - HIV AIDS (Auckl)
JT  - HIV/AIDS (Auckland, N.Z.)
JID - 101515943
PMC - PMC6913252
OTO - NOTNLM
OT  - Ethiopia
OT  - HIV
OT  - HIV exposed infants
OT  - MTCT
OT  - risk factors
COIS- The authors report no conflicts of interest in this work.
EDAT- 2019/12/19 06:00
MHDA- 2019/12/19 06:01
PMCR- 2019/12/12
CRDT- 2019/12/19 06:00
PHST- 2019/06/30 00:00 [received]
PHST- 2019/11/28 00:00 [accepted]
PHST- 2019/12/19 06:00 [entrez]
PHST- 2019/12/19 06:00 [pubmed]
PHST- 2019/12/19 06:01 [medline]
PHST- 2019/12/12 00:00 [pmc-release]
AID - 221409 [pii]
AID - 10.2147/HIV.S221409 [doi]
PST - epublish
SO  - HIV AIDS (Auckl). 2019 Dec 12;11:343-350. doi: 10.2147/HIV.S221409. eCollection 
      2019.