PMID- 31852710 OWN - NLM STAT- MEDLINE DCOM- 20201110 LR - 20221207 IS - 2044-6055 (Electronic) IS - 2044-6055 (Linking) VI - 9 IP - 12 DP - 2019 Dec 17 TI - Cross-sectional study of the association between long working hours and pre-diabetes: 2010-2017 Korea national health and nutrition examination survey. PG - e033579 LID - 10.1136/bmjopen-2019-033579 [doi] LID - e033579 AB - OBJECTIVE: Long working hours have been shown to raise the risk of various health outcomes. However, epidemiological evidence has shown inconsistent result in relation to type 2 diabetes mellitus (T2DM) and the association between long working hours and pre-diabetes among non-diabetic adults remains largely unexplored. We thus aimed to investigate whether long working hours were linked with pre-diabetes as determined by glycated haemoglobin (HbA1c) level. DESIGN: Cross-sectional survey. PARTICIPANTS: This study included 6324 men and 4001 women without diabetes from the 2010 to 2017 Korean National Health and Nutrition Examination Survey. PRIMARY OUTCOME MEASURES: The study outcome of interest was pre-diabetes, defined as HbA1c values 5.7% to 6.4% RESULTS: Logistic regression was performed to obtain the ORs for pre-diabetes according to categories of work hour (40 hours/week, 41 to 52 hours/week, >52 hours/week), after adjusting for relevant covariates. Of the 10 325 eligible participants, 2261 (34.4%) men and 1317 (31.0%) women had pre-diabetes. No statistically significant relationship was found for women. In men, extended working hours (>52 hours per week) was associated with an increased likelihood of pre-diabetes, after adjustment for age, educational attainment, monthly household income, lifestyle related factors, perceived stress, family history of diabetes, hypertension, hypercholesterolaemia and other covariates (adjusted OR=1.22; 95% CI 1.03 to 1.46). In the subgroup analysis by occupational categories, the association was only apparent among men in blue-collar worker groups. CONCLUSION: Extended working hours were significantly related to pre-diabetes in men, with no statistically significant association observed for women. Further subgroup analysis by occupational categories revealed that the increased odds of pre-diabetes associated with long working hours was only apparent among male workers of blue-collar occupations and shift workers. CI - (c) Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. FAU - Baek, Yunseng AU - Baek Y AD - Premedical courses, Yonsei University College of Medicine, Seoul, Korea (the Republic of). FAU - Kim, Minseok AU - Kim M AD - Premedical courses, Yonsei University College of Medicine, Seoul, Korea (the Republic of). FAU - Kim, Gyu Ri AU - Kim GR AUID- ORCID: 0000-0003-3624-3971 AD - Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea (the Republic of) ecpark@yuhs.ac gyurikim@yuhs.ac. FAU - Park, Eun-Cheol AU - Park EC AUID- ORCID: 0000-0002-2306-5398 AD - Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea (the Republic of) ecpark@yuhs.ac gyurikim@yuhs.ac. AD - Department of Preventive Medicine and Institute of Health Services Research, Yonsei University College of Medicine, Seoul, Korea (the Republic of). LA - eng PT - Journal Article DEP - 20191217 PL - England TA - BMJ Open JT - BMJ open JID - 101552874 RN - 0 (Glycated Hemoglobin A) SB - IM MH - Adult MH - Age Distribution MH - Cross-Sectional Studies MH - Female MH - Glycated Hemoglobin/analysis MH - Humans MH - Logistic Models MH - Male MH - Middle Aged MH - Nutrition Surveys MH - Prediabetic State/*epidemiology MH - Republic of Korea/epidemiology MH - Risk Factors MH - Sex Distribution MH - *Social Class MH - *Work PMC - PMC6937098 OTO - NOTNLM OT - Hba1c OT - glucose metabolism OT - pre-diabetes OT - working hours COIS- Competing interests: None declared. EDAT- 2019/12/20 06:00 MHDA- 2020/11/11 06:00 PMCR- 2019/12/17 CRDT- 2019/12/20 06:00 PHST- 2019/12/20 06:00 [entrez] PHST- 2019/12/20 06:00 [pubmed] PHST- 2020/11/11 06:00 [medline] PHST- 2019/12/17 00:00 [pmc-release] AID - bmjopen-2019-033579 [pii] AID - 10.1136/bmjopen-2019-033579 [doi] PST - epublish SO - BMJ Open. 2019 Dec 17;9(12):e033579. doi: 10.1136/bmjopen-2019-033579.