PMID- 31853177 OWN - NLM STAT- MEDLINE DCOM- 20200709 LR - 20200709 IS - 1178-2005 (Electronic) IS - 1176-9106 (Print) IS - 1176-9106 (Linking) VI - 14 DP - 2019 TI - Convergent Validity and Minimal Clinically Important Difference of the Maugeri Foundation Respiratory Failure Questionnaire (MRF-28) and the Chronic Obstructive Pulmonary Disease-Specific Health-Related Quality of Life questionnaire (VQ11). PG - 2895-2903 LID - 10.2147/COPD.S222165 [doi] AB - PURPOSE: Short and easy questionnaires have been developed to assess the health-related quality of life (HRQoL) in patients with chronic obstructive pulmonary disease (COPD), such as the Maugeri Foundation Respiratory Failure Questionnaire (MRF-28) and the COPD-specific HRQoL Questionnaire (VQ11). Both are valid, reliable, and sensitive, but their minimal clinically important differences (MCID) are unknown. Consequently, this study aimed to confirm the convergent validities of the MRF-28 and VQ11 and establish their MCID. A retrospective design was used to evaluate the effect of individual home-based pulmonary rehabilitation (PR) in 400 COPD patients. PATIENTS AND METHODS: Exercise tolerance, anxiety and depression based on the Hospital Anxiety and Depression Scale (HADS), and HRQoL using three questionnaires (MRF-28, VQ11, and the Visual Simplified Respiratory Questionnaire: VSRQ) were assessed before and after an individualized home-based PR program (5 sessions of 30-45 mins/week for 8 weeks, including a weekly session supervised by a team member). RESULTS: PR improved all measured variables (p < 0.0001). The correlations were significant (p < 0.0001) between VSRQ and MRF-28 (r = -0.685 at baseline and r = -0.686 after the PR program), and between VSRQ and VQ11 (r = -0.691 at baseline and r = -0.753 after the PR program). Moreover, changes in score (delta between after and before PR program) of VSRQ were also significantly correlated (p < 0.0001) to changes in score of MRF-28 (r = -0.372) and VQ11 (r = -0.423). Last, we calculated MCID of -5.2 and -2.0 units for MRF-28 and VQ11, respectively. CONCLUSION: The MRF-28 and VQ11 can be used in routine practice to evaluate the effects of PR on the HRQoL of COPD patients, with MCID of -5.2 and -2.0, respectively. CI - (c) 2019 Coquart et al. FAU - Coquart, Jeremy B AU - Coquart JB AUID- ORCID: 0000-0001-6515-7736 AD - Universite de Rouen-Normandie, UFR STAPS, CETAPS, EA 3832, Mont Saint Aignan F-76821, France. FAU - Heutte, Natacha AU - Heutte N AUID- ORCID: 0000-0002-1620-6105 AD - Universite de Rouen-Normandie, UFR STAPS, CETAPS, EA 3832, Mont Saint Aignan F-76821, France. FAU - Terce, Gaelle AU - Terce G AD - Centre Hospitalier de Bethune, Service de Pneumologie et de Rehabilitation Respiratoire, Beuvry F-62660, France. FAU - Grosbois, Jean-Marie AU - Grosbois JM AD - FormAction Sante, Perenchies F-59840, France. LA - eng PT - Journal Article DEP - 20191213 PL - New Zealand TA - Int J Chron Obstruct Pulmon Dis JT - International journal of chronic obstructive pulmonary disease JID - 101273481 SB - IM MH - Anxiety/diagnosis/physiopathology MH - Depression/diagnosis/physiopathology MH - Exercise Therapy MH - Exercise Tolerance MH - Female MH - Health Education MH - Home Care Services MH - Humans MH - Male MH - Middle Aged MH - Minimal Clinically Important Difference MH - Outcome Assessment, Health Care/*methods MH - Psychiatric Rehabilitation MH - *Pulmonary Disease, Chronic Obstructive/physiopathology/psychology/rehabilitation MH - *Quality of Life MH - *Surveys and Questionnaires MH - *Treatment Outcome PMC - PMC6916677 OTO - NOTNLM OT - VSRQ OT - home-based pulmonary rehabilitation OT - visual simplified respiratory questionnaire COIS- JMG received financial support from Adair, Aeris Sante, Bastide, France Oxygene, Homeperf, LVL, Medopale, NorOx, Orkyn, Santelys, SOS Oxygene, Sysmed, VitalAire, and ARS Hauts-de-France for the home-based PR program. The remaining authors report no conflicts of interest in this work. EDAT- 2019/12/20 06:00 MHDA- 2020/07/10 06:00 PMCR- 2019/12/13 CRDT- 2019/12/20 06:00 PHST- 2019/07/06 00:00 [received] PHST- 2019/09/23 00:00 [accepted] PHST- 2019/12/20 06:00 [entrez] PHST- 2019/12/20 06:00 [pubmed] PHST- 2020/07/10 06:00 [medline] PHST- 2019/12/13 00:00 [pmc-release] AID - 222165 [pii] AID - 10.2147/COPD.S222165 [doi] PST - epublish SO - Int J Chron Obstruct Pulmon Dis. 2019 Dec 13;14:2895-2903. doi: 10.2147/COPD.S222165. eCollection 2019.