PMID- 31864724 OWN - NLM STAT- MEDLINE DCOM- 20200526 LR - 20200526 IS - 1873-3778 (Electronic) IS - 0021-9673 (Linking) VI - 1615 DP - 2020 Mar 29 TI - Preparation of core-shell magnetic molecularly imprinted polymers for extraction of patulin from juice samples. PG - 460751 LID - S0021-9673(19)31196-3 [pii] LID - 10.1016/j.chroma.2019.460751 [doi] AB - In this study, a novel magnetic molecularly imprinted polymer (MMIP) was prepared by surface imprinting technology using 2-oxin and 6-HNA as dual virtual templates and 4-vinyl pyridine (4-VP) as the functional monomer for extraction of patulin (PAT) from the surface of magnetic nanoparticles. MMIPs were characterized by fourier transformed infrared (FT-IR) spectroscopy, X-ray diffraction, and vibrating sample magnetometry. The results showed that the molecularly imprinted polymer (MIP) was successfully coupled with magnetic nanoparticles and could be used as a magnetic selective recognition material. Moreover, MMIPs have a greater adsorption capacity for PAT than conventional MIPs. The magnetic dispersion solid-phase extraction procedure was optimized and then combined with liquid chromatography-tandem mass spectrometry (MDSPE-LC-MS/MS) for detection of PAT in juice samples. The method showed excellent analytical performance in terms of linearity (ranged between 0.5 mug L(-1) and 100 mug L(-1)with correlation coefficients (r) higher than 0.999) and limit of detection (LOD) (0.1 mug L(-1), S/N = 3). At three spiking concentrations (1, 10, and 50 mug L(-1)), the mean recoveries were ranged between 79.4% and 97.9% with relative standard deviations (RSDs) < 4.7% (n = 3). CI - Copyright (c) 2019. Published by Elsevier B.V. FAU - Zhao, Minjuan AU - Zhao M AD - Institute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China. FAU - Shao, Hua AU - Shao H AD - Institute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China. Electronic address: nkshaohua@163.com. FAU - Ma, Jun AU - Ma J AD - Institute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China. FAU - Li, Hui AU - Li H AD - Institute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China. FAU - He, Yahui AU - He Y AD - Institute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China; Beijing Technology and Business University, 100048, PR China. FAU - Wang, Miao AU - Wang M AD - Institute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China. FAU - Jin, Fen AU - Jin F AD - Institute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China. FAU - Wang, Jing AU - Wang J AD - Institute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China. FAU - Abd El-Aty, A M AU - Abd El-Aty AM AD - State Key Laboratory of Biobased Material and Green Papermaking, College of Food Science and Engineering, Qilu University of Technology, Shandong Academy of Science, Jinan 250353, China; Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, 12211 Giza, Egypt; Department of Medical Pharmacology, Medical Faculty, Ataturk University, 25240 Erzurum, Turkey. Electronic address: abdelaty44@hotmail.com. FAU - Hacimuftuoglu, Ahmet AU - Hacimuftuoglu A AD - Department of Medical Pharmacology, Medical Faculty, Ataturk University, 25240 Erzurum, Turkey. FAU - Yan, Feiyan AU - Yan F AD - Institute of Quality Standards & Testing Technology for Agro-Products, Guangxi Academy of Agricultural Sciences, Nanning 530000, PR China. FAU - Wang, Yanli AU - Wang Y AD - Institute of Quality Standards & Testing Technology for Agro-Products, Guangxi Academy of Agricultural Sciences, Nanning 530000, PR China. FAU - She, Yongxin AU - She Y AD - Institute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China. Electronic address: sheyongxin@caas.cn. LA - eng PT - Journal Article DEP - 20191129 PL - Netherlands TA - J Chromatogr A JT - Journal of chromatography. A JID - 9318488 RN - 0 (Polymers) RN - 95X2BV4W8R (Patulin) SB - IM MH - Adsorption MH - Chromatography, Liquid MH - Food Analysis/*methods MH - Food Contamination/*analysis MH - Limit of Detection MH - Magnetic Phenomena MH - Molecular Imprinting MH - Nanoparticles/*chemistry MH - Patulin/*analysis/isolation & purification MH - Polymers/*chemical synthesis MH - Solid Phase Extraction MH - Spectroscopy, Fourier Transform Infrared MH - Tandem Mass Spectrometry MH - X-Ray Diffraction OTO - NOTNLM OT - HPLC-DAD OT - Juice OT - LC-MS/MS OT - Magnetic dispersion solid-phase extraction OT - Magnetic molecularly imprinted polymers OT - Patulin COIS- Declaration of Competing Interest Authors have declared no conflicts of interest. EDAT- 2019/12/23 06:00 MHDA- 2020/05/27 06:00 CRDT- 2019/12/23 06:00 PHST- 2019/10/24 00:00 [received] PHST- 2019/11/28 00:00 [revised] PHST- 2019/11/28 00:00 [accepted] PHST- 2019/12/23 06:00 [pubmed] PHST- 2020/05/27 06:00 [medline] PHST- 2019/12/23 06:00 [entrez] AID - S0021-9673(19)31196-3 [pii] AID - 10.1016/j.chroma.2019.460751 [doi] PST - ppublish SO - J Chromatogr A. 2020 Mar 29;1615:460751. doi: 10.1016/j.chroma.2019.460751. Epub 2019 Nov 29.