PMID- 31868317
OWN - NLM
STAT- MEDLINE
DCOM- 20210208
LR  - 20210208
IS  - 1522-726X (Electronic)
IS  - 1522-1946 (Linking)
VI  - 96
IP  - 1
DP  - 2020 Jul
TI  - Outcomes of primary percutaneous cardiac intervention for ST elevation myocardial 
      infarction with a saphenous vein graft culprit.
PG  - E75-E83
LID - 10.1002/ccd.28662 [doi]
AB  - BACKGROUND: Patients treated with primary percutaneous coronary intervention 
      (pPCI) for ST elevation myocardial infarction (STEMI) who have a history of 
      coronary artery bypass grafting (CABG) are at high risk of adverse cardiovascular 
      outcomes. Data on the risk of a saphenous vein graft (SVG)-infarct-related artery 
      (IRA) compared to other culprit vessels are sparse. METHODS: The study was based 
      on a prospectively collected registry of 2,405 consecutive patients with STEMI 
      attending a tertiary medical center in 2001-2017. Patients with an SVG-IRA (n 
      = 172) were compared with patients with native vessel disease (n = 2,333) for 
      mortality and major adverse cardiac events (MACE), which included death, 
      myocardial infarction (MI), target vessel revascularization (TVR), and coronary 
      artery bypass surgery (CABG) at 1 month and 3 years. RESULTS: The SVG-IRA group 
      was significantly older than the native vessel group (p = .05), with no 
      between-group differences in rates of male patients (76 vs. 82%, p = .59), 
      diabetes (24.2 vs. 26.2%, p = .73), and renal failure (18.8 vs. 9.2%, p = .25). 
      Mortality was higher in the SVG-IRA group at 1 month (13.9 vs. 2.5%, p < .01) and 
      3 years (23.9 vs. 7.4%, p < .01). At 3 years, SVG-IRA was associated with the 
      highest rates of MACE (55.6%), compared with native vessel disease. After 
      correction for confounders, SVG-IRA remained an independent risk factor for MACE 
      both at 1 month (HR-2.08, 95%CI 1.72-3.11, p < .01) and 3 years (HR-2.01, 95%CI 
      1.28-3.09, p < .01). CONCLUSION: Among patients treated with pPCI for STEMI, 
      outcomes are worse when the culprit is an SVG.
CI  - (c) 2019 Wiley Periodicals, Inc.
FAU - Kheifets, Mark
AU  - Kheifets M
AUID- ORCID: 0000-0002-7735-4419
AD  - Department of Cardiology, Rabin Medical Center, Petach Tikva and the Sackler 
      Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
AD  - Department of Internal Medicine B, Meir Medical Center, Kfar-Saba, Israel.
FAU - Vaknin-Assa, Hana
AU  - Vaknin-Assa H
AD  - Department of Cardiology, Rabin Medical Center, Petach Tikva and the Sackler 
      Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Greenberg, Gabriel
AU  - Greenberg G
AD  - Department of Cardiology, Rabin Medical Center, Petach Tikva and the Sackler 
      Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Assali, Abid
AU  - Assali A
AD  - Department of Cardiology, Rabin Medical Center, Petach Tikva and the Sackler 
      Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Kornowski, Ran
AU  - Kornowski R
AUID- ORCID: 0000-0002-7708-8253
AD  - Department of Cardiology, Rabin Medical Center, Petach Tikva and the Sackler 
      Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
FAU - Perl, Leor
AU  - Perl L
AUID- ORCID: 0000-0002-0625-7937
AD  - Department of Cardiology, Rabin Medical Center, Petach Tikva and the Sackler 
      Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Observational Study
DEP - 20191223
PL  - United States
TA  - Catheter Cardiovasc Interv
JT  - Catheterization and cardiovascular interventions : official journal of the 
      Society for Cardiac Angiography & Interventions
JID - 100884139
SB  - IM
MH  - Aged
MH  - Coronary Artery Bypass/*adverse effects/mortality
MH  - Female
MH  - Graft Occlusion, Vascular/diagnostic imaging/etiology/mortality/*therapy
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Percutaneous Coronary Intervention/adverse effects/mortality
MH  - Prospective Studies
MH  - Registries
MH  - Risk Assessment
MH  - Risk Factors
MH  - ST Elevation Myocardial Infarction/diagnostic imaging/etiology/mortality/*therapy
MH  - Saphenous Vein/diagnostic imaging/*transplantation
MH  - Time Factors
MH  - Treatment Outcome
OTO - NOTNLM
OT  - STEMI
OT  - SVG-IRA
OT  - pPCI
EDAT- 2019/12/24 06:00
MHDA- 2021/02/09 06:00
CRDT- 2019/12/24 06:00
PHST- 2019/09/10 00:00 [received]
PHST- 2019/11/10 00:00 [revised]
PHST- 2019/12/07 00:00 [accepted]
PHST- 2019/12/24 06:00 [pubmed]
PHST- 2021/02/09 06:00 [medline]
PHST- 2019/12/24 06:00 [entrez]
AID - 10.1002/ccd.28662 [doi]
PST - ppublish
SO  - Catheter Cardiovasc Interv. 2020 Jul;96(1):E75-E83. doi: 10.1002/ccd.28662. Epub 
      2019 Dec 23.