PMID- 31868676
OWN - NLM
STAT- MEDLINE
DCOM- 20201013
LR  - 20201013
IS  - 2214-3602 (Electronic)
VI  - 7
IP  - 1
DP  - 2020
TI  - Dysautonomia as the Presenting Symptom in Anti-Muscle-Specific Kinase Antibody 
      Myasthenia Gravis.
PG  - 47-50
LID - 10.3233/JND-190411 [doi]
AB  - In an minority of Myasthenia Gravis (MG) patients, the autoantibodies bind to 
      muscle-specific kinase (MUSK). These MuSK antibody-mediated MG (MuSK MG) patients 
      are not only immunologically distinct, but also have different characteristic 
      clinical features. Dysautonomia in MG is rarely reported. We present a MuSK MG 
      patient who suffered from life-threatening autonomic dysfunction. MuSK MG should 
      be considered in the differential diagnosis in cases of unclarified dysautonomia, 
      given the potential for treatment in those cases.
FAU - Bekooij, T J S
AU  - Bekooij TJS
AD  - Department of Neurology, Haaglanden Medical Centre Westeinde, The Hague, The 
      Netherlands.
FAU - Gilhuis, H J
AU  - Gilhuis HJ
AD  - Department of Neurology, Reinier de Graaf Hospital, Delft, The Netherlands.
FAU - Dawson, L
AU  - Dawson L
AD  - Department of Neurology, Reinier de Graaf Hospital, Delft, The Netherlands.
FAU - Niks, E H
AU  - Niks EH
AD  - Department of Neurology, Leiden University Medical Centre, The Netherlands.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Netherlands
TA  - J Neuromuscul Dis
JT  - Journal of neuromuscular diseases
JID - 101649948
RN  - 0 (Autoantibodies)
RN  - 0 (Receptors, Cholinergic)
RN  - EC 2.7.10.1 (MUSK protein, human)
RN  - EC 2.7.10.1 (Receptor Protein-Tyrosine Kinases)
SB  - IM
MH  - Autoantibodies/blood
MH  - Diagnosis, Differential
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Myasthenia Gravis/complications/diagnosis/immunology
MH  - *Primary Dysautonomias/diagnosis/etiology/immunology
MH  - Receptor Protein-Tyrosine Kinases/*immunology
MH  - Receptors, Cholinergic/*immunology
OTO - NOTNLM
OT  - Myasthenia gravis (MG)
OT  - anti-MuSK antibody myasthenia gravis (MuSK MG)
OT  - autonomic dysfunction
OT  - dysautonomia
OT  - muscle-specific kinase (MuSK)
EDAT- 2019/12/24 06:00
MHDA- 2020/10/21 06:00
CRDT- 2019/12/24 06:00
PHST- 2019/12/24 06:00 [pubmed]
PHST- 2020/10/21 06:00 [medline]
PHST- 2019/12/24 06:00 [entrez]
AID - JND190411 [pii]
AID - 10.3233/JND-190411 [doi]
PST - ppublish
SO  - J Neuromuscul Dis. 2020;7(1):47-50. doi: 10.3233/JND-190411.