PMID- 31869422 OWN - NLM STAT- MEDLINE DCOM- 20200511 LR - 20200511 IS - 1578-2735 (Electronic) IS - 1139-9287 (Linking) VI - 47 IP - 6 DP - 2019 Nov TI - Coexistence between personality disorders and substance use disorder. Madrid study about prevalence of dual pathology. PG - 218-28 AB - INTRODUCTION: Personality disorders (PD) and substance use disorders (SUD) have a high prevalence and an important health and socioeconomic impact so, it is interesting to study the relationship between them. The objectives of the study are: to compare the prevalence of SUD between patients with and without diagnosis of PD, to analyze if any PD is related to the SUD, and if a specific PD is associated with a specific SUD. MATERIAL AND METHODS: Cross-sectional study in 837 patients from centers of attention to drug addiction and mental health in Madrid, Spain. The Mini International Neuropsychiatric Interview (MINI) and the Personality Diagnostic Questionnaire-4+ (PDQ4+) are used to detect mental disorder and PD, respectively. RESULTS: SUD is significantly higher in antisocial PD (p<0.01); sedative (p<0.01) and alcohol (p<0.05) use disorder in borderline PD; cocaine (p<0.05) and alcohol (p<0.01) use disorder in paranoid PD; and alcohol use disorder in histrionic PD (p<0.01). The SUD for cocaine is lower in obsessive- compulsive PD (p<0.05) and depressive PD (p<0.01). There is a positive correlation between the number of PD of a subject and the number of SUD that it presents. The risk of an alcohol [OR of 1,08 CI (1,01-1,16)] or sedatives [OR of 1,08 CI (1,001-1,17)] use disorders increases if an individual presents more than one type of PD. CONCLUSIONS: There is not differences of SUD prevalence between PD and not PD groups. We found an association between SUD and PD of cluster B (antisocial, borderline and histrionic) and also with paranoid PD. The SUD are more common among man with the exception of sedatives. FAU - Gonzalez, Ester AU - Gonzalez E AD - Servicio de Psiquiatria. Hospital 12 de Octubre, Madrid, Espana. FAU - Arias, Francisco AU - Arias F AD - Servicio de Psiquiatria. Hospital 12 de Octubre, Madrid, Espana. FAU - Szerman, Nestor AU - Szerman N AD - Servicio de Psiquiatria. Hospital Gregorio Maranon, Madrid, Espana. FAU - Vega, Pablo AU - Vega P AD - Instituto de Adicciones, Madrid, Espana. FAU - Mesias, Beatriz AU - Mesias B AD - Instituto de Adicciones, Madrid, Espana. FAU - Basurte, Ignacio AU - Basurte I AD - Servicio de Psiquiatria. Hospital Gregorio Maranon, Madrid, Espana. LA - eng PT - Journal Article PT - Multicenter Study DEP - 20191101 PL - Spain TA - Actas Esp Psiquiatr JT - Actas espanolas de psiquiatria JID - 100886502 SB - IM MH - Adult MH - Alcoholism/diagnosis/epidemiology MH - Antisocial Personality Disorder/diagnosis/epidemiology MH - Cocaine-Related Disorders/diagnosis/epidemiology MH - Cross-Sectional Studies MH - Depression/diagnosis/epidemiology MH - Diagnosis, Dual (Psychiatry) MH - Female MH - Histrionic Personality Disorder/diagnosis/epidemiology MH - Humans MH - Male MH - Marijuana Abuse/diagnosis/epidemiology MH - Obsessive-Compulsive Disorder/diagnosis/epidemiology MH - Opioid-Related Disorders/diagnosis/epidemiology MH - Paranoid Personality Disorder/diagnosis/epidemiology MH - Personality Disorders/diagnosis/*epidemiology MH - Prevalence MH - Spain/epidemiology MH - Substance Abuse Treatment Centers/statistics & numerical data MH - Substance-Related Disorders/diagnosis/*epidemiology EDAT- 2019/12/24 06:00 MHDA- 2020/05/12 06:00 CRDT- 2019/12/24 06:00 PHST- 2019/11/01 00:00 [received] PHST- 2019/11/01 00:00 [accepted] PHST- 2019/12/24 06:00 [entrez] PHST- 2019/12/24 06:00 [pubmed] PHST- 2020/05/12 06:00 [medline] PST - ppublish SO - Actas Esp Psiquiatr. 2019 Nov;47(6):218-28. Epub 2019 Nov 1.