PMID- 31872013 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 2352-3409 (Electronic) IS - 2352-3409 (Linking) VI - 28 DP - 2020 Feb TI - Dataset on effects of perinatal exposure to propylthiouracil on serum T4, body weight gain, day of eye opening and brain monoamine contents in offspring mice. PG - 104900 LID - 10.1016/j.dib.2019.104900 [doi] LID - 104900 AB - Physical growth and brain development need sufficient thyroid hormone (TH). This dataset describes serum T4 level, body weight gain and day of eye opening in offspring mice exposed to the TH synthesis inhibitor propylthiouracil (PTU) from gestational day (GD) 15 to postnatal day (PND) 25. This dataset also describes content of dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), 3-methoxytyramine (3-MT), 5-HT, and 5-hydroxyindoleacetic acid (5-HIAA) and their turnover in the hypothalamus, hippocampus, and nucleus accumbens of male offspring mice perinatally exposed to PTU. These data are referred by a research article entitled "Hyperactive behavioral phenotypes and an altered brain monoaminergic state in male offspring mice with perinatal hypothyroidism" [1]. CI - (c) 2019 The Author(s). FAU - Umezu, Toyoshi AU - Umezu T AD - Center for Health and Environmental Risk Research, National Institute for Environmental Studies, Tsukuba, Ibaraki, 305-8506, Japan. FAU - Kita, Taizo AU - Kita T AD - Graduate School of Food and Nutrition, Kyushu Nutrition Welfare University, Kitakyushu, Fukuoka, 803-8511, Japan. FAU - Morita, Masatoshi AU - Morita M AD - Graduate School of Agriculture, Ehime University, Matsuyama, Ehime, 790-8577, Japan. LA - eng PT - Journal Article DEP - 20191129 PL - Netherlands TA - Data Brief JT - Data in brief JID - 101654995 PMC - PMC6909211 OTO - NOTNLM OT - Growth OT - Hypothyroidism OT - Monoaminergic neurotransmitter OT - Mouse OT - Neurodevelopment EDAT- 2019/12/25 06:00 MHDA- 2019/12/25 06:01 PMCR- 2019/11/29 CRDT- 2019/12/25 06:00 PHST- 2019/11/08 00:00 [received] PHST- 2019/11/21 00:00 [revised] PHST- 2019/11/21 00:00 [accepted] PHST- 2019/12/25 06:00 [entrez] PHST- 2019/12/25 06:00 [pubmed] PHST- 2019/12/25 06:01 [medline] PHST- 2019/11/29 00:00 [pmc-release] AID - S2352-3409(19)31255-7 [pii] AID - 104900 [pii] AID - 10.1016/j.dib.2019.104900 [doi] PST - epublish SO - Data Brief. 2019 Nov 29;28:104900. doi: 10.1016/j.dib.2019.104900. eCollection 2020 Feb.