PMID- 31876755
OWN - NLM
STAT- MEDLINE
DCOM- 20200113
LR  - 20230905
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 98
IP  - 52
DP  - 2019 Dec
TI  - Clinical efficacy and safety of Shenqi Fuzheng injection for the treatment of 
      chronic heart failure: Protocol for a meta-analysis and systematic review.
PG  - e18556
LID - 10.1097/MD.0000000000018556 [doi]
LID - e18556
AB  - BACKGROUND: Chronic heart failure (CHF) is one of the most serious cardiovascular 
      diseases. Shenqi Fuzheng injection (SQFZI), as a Chinese herbal injection, is 
      usually used for the treatment of CHF. However, the clinical evidence of SQFZI 
      for the treatment of CHF is unclear. METHODS: Two researchers will dependently 
      search literatures of SQFZI for CHF from Chinese National Knowledge 
      Infrastructure database, VIP database, Chinese Biological and Medicine database, 
      Wangfang database, MEDLINE, EMBASE, Cochrane Library and Web of Science. These 
      inclusive data of included studies will be conducted by RevMan 5.3 software. 
      RESULTS: This meta-analysis and systematic review will provide a series of 
      outcome measures to verify clinical efficacy and safety of SQFZI for treating 
      CHF, including New York Heart Association (NYHA) function classification, left 
      ventricular ejection fraction, left ventricular end-diastolic dimension, cardiac 
      output, stroke volume, brain natriuretic peptide, N-terminal pro-brain 
      natriuretic peptide, and adverse events. CONCLUSIONS: This meta-analysis and 
      systematic review will provide up-to-date clinical evidence to assess SQFZI 
      treatment efficacy for CHF patients.
FAU - Wang, Chuan
AU  - Wang C
AD  - Department of Pharmacology, College of Pharmacy, Shaanxi University of Chinese 
      Medicine, Xianyang.
AD  - Key Laboratory of Pharmacodynamics and Material Basis of Chinese Medicine of 
      Shaanxi Administration of Traditional Chinese Medicine.
AD  - Subject Innovation Team of Shaanxi University of Chinese Medicine.
FAU - Yao, Dongfeng
AU  - Yao D
AD  - Department of Pharmacology, College of Pharmacy, Shaanxi University of Chinese 
      Medicine, Xianyang.
FAU - Zhang, Pan
AU  - Zhang P
AD  - Department of Pharmacology, College of Pharmacy, Shaanxi University of Chinese 
      Medicine, Xianyang.
FAU - Xie, Xiaowei
AU  - Xie X
AD  - Department of Pharmacology, College of Pharmacy, Shaanxi University of Chinese 
      Medicine, Xianyang.
FAU - Wang, Bin
AU  - Wang B
AD  - Department of Pharmacology, College of Pharmacy, Shaanxi University of Chinese 
      Medicine, Xianyang.
AD  - Key Laboratory of Pharmacodynamics and Material Basis of Chinese Medicine of 
      Shaanxi Administration of Traditional Chinese Medicine.
AD  - Subject Innovation Team of Shaanxi University of Chinese Medicine.
FAU - Liu, Jiping
AU  - Liu J
AD  - Department of Pharmacology, College of Pharmacy, Shaanxi University of Chinese 
      Medicine, Xianyang.
AD  - Key Laboratory of Pharmacodynamics and Material Basis of Chinese Medicine of 
      Shaanxi Administration of Traditional Chinese Medicine.
AD  - Subject Innovation Team of Shaanxi University of Chinese Medicine.
FAU - Zhang, Zhen
AU  - Zhang Z
AD  - Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources 
      Industrialization, Shaanxi University of Chinese Medicine, China.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Cardiotonic Agents)
RN  - 0 (Drugs, Chinese Herbal)
RN  - 0 (shenqi fuzheng)
SB  - IM
MH  - Cardiotonic Agents/adverse effects/*therapeutic use
MH  - Drugs, Chinese Herbal/administration & dosage/adverse effects/*therapeutic use
MH  - Heart Failure/*drug therapy
MH  - Humans
MH  - Injections
MH  - Treatment Outcome
MH  - Meta-Analysis as Topic
MH  - Systematic Review as Topic
PMC - PMC6946559
COIS- The authors report no conflicts of interest.
EDAT- 2019/12/27 06:00
MHDA- 2020/01/14 06:00
PMCR- 2019/12/27
CRDT- 2019/12/27 06:00
PHST- 2019/12/27 06:00 [entrez]
PHST- 2019/12/27 06:00 [pubmed]
PHST- 2020/01/14 06:00 [medline]
PHST- 2019/12/27 00:00 [pmc-release]
AID - 00005792-201912270-00054 [pii]
AID - MD-D-19-09131 [pii]
AID - 10.1097/MD.0000000000018556 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2019 Dec;98(52):e18556. doi: 10.1097/MD.0000000000018556.