PMID- 31881654
OWN - NLM
STAT- MEDLINE
DCOM- 20200902
LR  - 20200902
IS  - 2072-6643 (Electronic)
IS  - 2072-6643 (Linking)
VI  - 12
IP  - 1
DP  - 2019 Dec 25
TI  - Antidiabetic Properties of Curcumin II: Evidence from In Vivo Studies.
LID - 10.3390/nu12010058 [doi]
LID - 58
AB  - Type 2 diabetes mellitus (T2DM) is a growing metabolic disease characterized by 
      insulin resistance and hyperglycemia. Current preventative and treatment 
      approaches to insulin resistance and T2DM lack in efficacy, resulting in the need 
      for new approaches to prevent and treat the disease. In recent years, 
      epidemiological studies have suggested that diets rich in fruits and vegetables 
      have beneficial health effects, including protection against insulin resistance 
      and T2DM. Curcumin, a polyphenol found in turmeric, and curcuminoids have been 
      reported to have antioxidant, anti-inflammatory, hepatoprotective, 
      nephroprotective, neuroprotective, immunomodulatory and antidiabetic properties. 
      The current review (II of II) summarizes the existing in vivo studies examining 
      the antidiabetic effects of curcumin.
FAU - Den Hartogh, Danja J
AU  - Den Hartogh DJ
AD  - Department of Health Sciences, Brock University, St. Catharines, ON L2S 3A1, 
      Canada.
AD  - Centre for Bone and Muscle Health, Brock University, St. Catharines, ON L2S 3A1, 
      Canada.
FAU - Gabriel, Alessandra
AU  - Gabriel A
AD  - Department of Health Sciences, Brock University, St. Catharines, ON L2S 3A1, 
      Canada.
FAU - Tsiani, Evangelia
AU  - Tsiani E
AUID- ORCID: 0000-0003-4218-5851
AD  - Department of Health Sciences, Brock University, St. Catharines, ON L2S 3A1, 
      Canada.
AD  - Centre for Bone and Muscle Health, Brock University, St. Catharines, ON L2S 3A1, 
      Canada.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20191225
PL  - Switzerland
TA  - Nutrients
JT  - Nutrients
JID - 101521595
RN  - 0 (Hypoglycemic Agents)
RN  - IT942ZTH98 (Curcumin)
SB  - IM
MH  - Animals
MH  - *Curcumin
MH  - Diabetes Mellitus, Experimental
MH  - Diabetes Mellitus, Type 2/drug therapy/physiopathology
MH  - Disease Progression
MH  - Female
MH  - Humans
MH  - *Hypoglycemic Agents
MH  - Insulin Resistance
MH  - Male
MH  - Mice
MH  - Oxidative Stress/drug effects
MH  - Rats
PMC - PMC7019668
OTO - NOTNLM
OT  - animal studies
OT  - curcumin
OT  - curcuminoids
OT  - diabetes
OT  - human studies
OT  - in vivo
OT  - insulin resistance
COIS- The authors declare no conflict of interest.
EDAT- 2019/12/29 06:00
MHDA- 2020/09/04 06:00
PMCR- 2020/01/01
CRDT- 2019/12/29 06:00
PHST- 2019/11/15 00:00 [received]
PHST- 2019/12/19 00:00 [revised]
PHST- 2019/12/24 00:00 [accepted]
PHST- 2019/12/29 06:00 [entrez]
PHST- 2019/12/29 06:00 [pubmed]
PHST- 2020/09/04 06:00 [medline]
PHST- 2020/01/01 00:00 [pmc-release]
AID - nu12010058 [pii]
AID - nutrients-12-00058 [pii]
AID - 10.3390/nu12010058 [doi]
PST - epublish
SO  - Nutrients. 2019 Dec 25;12(1):58. doi: 10.3390/nu12010058.