PMID- 31884545 OWN - NLM STAT- MEDLINE DCOM- 20200420 LR - 20210128 IS - 1614-7499 (Electronic) IS - 0944-1344 (Linking) VI - 27 IP - 7 DP - 2020 Mar TI - Organochlorine pesticides in the surrounding soils of POPs destruction facility: source fingerprinting, human health, and ecological risks assessment. PG - 7328-7340 LID - 10.1007/s11356-019-07183-7 [doi] AB - The elimination of persistent organic pollutants (POPs) obsolete pesticides stockpiles, particularly the organochlorine pesticides (OCPs), is one of the critical environmental issues faced by many developing countries. This pioneering study aimed to investigate the occurrence, source fingerprinting, human health, and ecological risks of OCPs in the surroundings of the lone POPs pesticide destruction facility in Pakistan. The SigmaOCPs residual levels in soil ranged from 35.98 to 566.77 ng/g dry weight (dw), with a mean concentration of 174.42 + 111.62 ng/g (dw). The OCPs contamination levels in the soil followed the pattern as SigmaHCHs > Sigmaendrins > Sigmaendosulfans > dieldrin > Sigmaheptachlors > SigmaDDTs > Sigmachlordanes > methoxychlor. The SigmaHCHs residual concentrations were comparatively higher than the previous national and global soil studies. The recent accumulation of HCHs, DDTs, and heptachlor was observed in the study area as identified by beta-HCH/ summation operatorHCHs, (DDE + DDD)/SigmaDDTs, heptachlor/Sigmaheptachlor, and heptachlor exo-epoxide/heptachlor ratios. The OCPs' lifetime carcinogenic risk through ingestion, dermal, and inhalation exposure routes ranged from 1.65E-08 to 2.91E-07, whereas the noncarcinogenic hazard quotient (HQ) ranged from 9.12E-05 to 1.61E-03. The risk vulnerability among age groups was in the order: adult > toddler > child > teen > infant. The calculated risk levels were within an acceptable limit of one in a million (1 x 10(-6)) for carcinogenic risk and HQ < 1 for noncarcinogenic risk. The current OCPs residual levels, especially dieldrin and endrin, exhibited low to medium ecological risks when compared to various worldwide limits. The upsurge of the OCPs' environmental contamination levels over the years and consideration of the food chain transfer might amplify the human health and ecological risks intensities. FAU - Ali, Syeda Nazish AU - Ali SN AD - Sustainable Development Study Centre, Government College University, Lahore, 54000, Pakistan. FAU - Baqar, Mujtaba AU - Baqar M AD - Sustainable Development Study Centre, Government College University, Lahore, 54000, Pakistan. mujtababaqar@gcu.edu.pk. FAU - Mumtaz, Mehvish AU - Mumtaz M AD - School of Environment, Tsinghua University, Beijing, 100084, China. FAU - Ashraf, Uzma AU - Ashraf U AD - Department of Environmental Science and Policy, Lahore School of Economics, Lahore, 53200, Pakistan. FAU - Anwar, Muhammad Naveed AU - Anwar MN AD - Sustainable Development Study Centre, Government College University, Lahore, 54000, Pakistan. FAU - Qadir, Abdul AU - Qadir A AD - College of Earth and Environmental Sciences, University of the Punjab, Lahore, 54590, Pakistan. FAU - Ahmad, Sajid Rashid AU - Ahmad SR AD - College of Earth and Environmental Sciences, University of the Punjab, Lahore, 54590, Pakistan. FAU - Nizami, Abdul-Sattar AU - Nizami AS AD - Sustainable Development Study Centre, Government College University, Lahore, 54000, Pakistan. FAU - Jun, Huang AU - Jun H AD - School of Environment, Tsinghua University, Beijing, 100084, China. LA - eng PT - Journal Article DEP - 20191228 PL - Germany TA - Environ Sci Pollut Res Int JT - Environmental science and pollution research international JID - 9441769 RN - 0 (Environmental Pollutants) RN - 0 (Hydrocarbons, Chlorinated) RN - 0 (Pesticides) RN - 0 (Soil) RN - 0 (Water Pollutants, Chemical) SB - IM MH - Adolescent MH - Adult MH - Child, Preschool MH - China MH - *Environmental Pollutants MH - Humans MH - *Hydrocarbons, Chlorinated MH - Pakistan MH - *Pesticides MH - Soil MH - *Water Pollutants, Chemical OTO - NOTNLM OT - Ecological risk OT - Human health risk OT - Organochlorine pesticides contamination OT - Pesticide destruction facility EDAT- 2019/12/31 06:00 MHDA- 2020/04/21 06:00 CRDT- 2019/12/30 06:00 PHST- 2019/06/18 00:00 [received] PHST- 2019/11/25 00:00 [accepted] PHST- 2019/12/31 06:00 [pubmed] PHST- 2020/04/21 06:00 [medline] PHST- 2019/12/30 06:00 [entrez] AID - 10.1007/s11356-019-07183-7 [pii] AID - 10.1007/s11356-019-07183-7 [doi] PST - ppublish SO - Environ Sci Pollut Res Int. 2020 Mar;27(7):7328-7340. doi: 10.1007/s11356-019-07183-7. Epub 2019 Dec 28.