PMID- 31886093
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 11
IP  - 12
DP  - 2019 Dec 12
TI  - Significant Reduction of Elevated Triglycerides and Liver Fibrosis in Diabetic 
      Dyslipidemia with Saroglitazar: A Case Report.
PG  - e6361
LID - 10.7759/cureus.6361 [doi]
LID - e6361
AB  - Metabolic disorders are characterized by pathologies like visceral adiposity, 
      hypertension, type 2 diabetes mellitus (T2DM), dyslipidemia, impaired glucose 
      tolerance, fatty liver, and so on, with insulin resistance being the main 
      contributing factor. Insulin resistance and diabetes mellitus are commonly 
      associated with elevated triglyceride levels. Among the available medications for 
      treating metabolic disorders, only Saroglitazar has a dual peroxisome 
      proliferator-activated receptor a + gamma action that can reduce high triglycerides 
      and improve insulin sensitivity. This medication may also reduce liver fibrosis 
      content. The present case report illustrates the efficacy of Saroglitazar in 
      reducing hypertriglyceridemia and liver stiffness as assessed by shear wave 
      elastography.
CI  - Copyright (c) 2019, Roy et al.
FAU - Roy, Sayak
AU  - Roy S
AD  - Internal Medicine, Calcutta Medical Research Institute Hospital, Kolkata, IND.
FAU - Ghosh, Abhijnan
AU  - Ghosh A
AD  - Pharmacology, The Institute of Post-Graduate Medical Education and Research, 
      Kolkata, IND.
LA  - eng
PT  - Case Reports
DEP - 20191212
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC6910614
OTO - NOTNLM
OT  - hypertriglyceridemia
OT  - saroglitazar
OT  - shear wave elastography
OT  - type 2 diabetes mellitus
COIS- The authors have declared that no competing interests exist.
EDAT- 2019/12/31 06:00
MHDA- 2019/12/31 06:01
PMCR- 2019/12/12
CRDT- 2019/12/31 06:00
PHST- 2019/12/31 06:00 [entrez]
PHST- 2019/12/31 06:00 [pubmed]
PHST- 2019/12/31 06:01 [medline]
PHST- 2019/12/12 00:00 [pmc-release]
AID - 10.7759/cureus.6361 [doi]
PST - epublish
SO  - Cureus. 2019 Dec 12;11(12):e6361. doi: 10.7759/cureus.6361.