PMID- 31889225
OWN - NLM
STAT- MEDLINE
DCOM- 20210118
LR  - 20210118
IS  - 1572-8595 (Electronic)
IS  - 1383-875X (Print)
IS  - 1383-875X (Linking)
VI  - 57
IP  - 1
DP  - 2020 Jan
TI  - The impact of catheter ablation of atrial fibrillation on the left atrial volume 
      and function: study using three-dimensional echocardiography.
PG  - 87-95
LID - 10.1007/s10840-019-00696-8 [doi]
AB  - PURPOSE: The exact correlation between the baseline left atrial (LA) volume (LAV) 
      and atrial fibrillation (AF) radiofrequency catheter ablation (RFCA) outcomes and 
      changes to the LA after AF RFCA has not yet been fully understood. We sought to 
      evaluate the serial changes in the LAV and LA function after RFCA using 3D 
      echocardiography. METHODS: Consecutive patients who received RFCA of paroxysmal 
      (PAF) or persistent AF (PeAF) at our center between January 2013 and March 2016 
      were included. Real-time 3D apical full-volume images were acquired, and a 3D 
      volumetric assessment was performed using an automated three-beat averaging 
      method. The LAV index (LAVI) was calculated and the LA ejection fraction (LAEF) 
      was calculated as [LAVmax - LAVmin]/LAVmax. RESULTS: Ninety-nine total patients 
      were enrolled, and the mean age was 58.0 +/- 8.2 years and 75 (74.7%) were male. 
      There were 59 (59.6%) PAF patients and the remaining 40 (40.4%) had PeAF. AF 
      recurred in 5 of 59 (8.5%) PAF and in 10 of 40 (25%) PeAF patients. The LAVImax 
      increased on 1 day, decreased at 3 months, and then increased again at 1 year but 
      was lower than that at baseline. The LAEF changes were similar to the volume 
      changes but were more prominent in PeAF than PAF patients. The baseline 3D 
      LAVImax was an independent predictor of AF recurrence after RFCA and the cut-off 
      value was 44.13 ml/m(2). CONCLUSION: In our study, even after 3 months of scar 
      formation due to ablation, structural remodeling of the LA continued. The changes 
      were more prominent in the non-recurrent, PeAF patients.
FAU - Hwang, Jongmin
AU  - Hwang J
AUID- ORCID: 0000-0001-9710-0945
AD  - Cardiovascular Center, Keimyung University Dongsan Hospital, 1035, 
      Dalgubeol-daero, Daegu, Dalseo-gu,, 42601, South Korea.
FAU - Park, Hyoung-Seob
AU  - Park HS
AUID- ORCID: 0000-0002-8042-1029
AD  - Cardiovascular Center, Keimyung University Dongsan Hospital, 1035, 
      Dalgubeol-daero, Daegu, Dalseo-gu,, 42601, South Korea. parkgyver@dsmc.or.kr.
FAU - Han, Seongwook
AU  - Han S
AUID- ORCID: 0000-0002-0496-7249
AD  - Cardiovascular Center, Keimyung University Dongsan Hospital, 1035, 
      Dalgubeol-daero, Daegu, Dalseo-gu,, 42601, South Korea.
FAU - Jun, Seung-Woon
AU  - Jun SW
AD  - Cardiovascular Center, Keimyung University Dongsan Hospital, 1035, 
      Dalgubeol-daero, Daegu, Dalseo-gu,, 42601, South Korea.
FAU - Kang, Na-Young
AU  - Kang NY
AD  - Cardiovascular Center, Keimyung University Dongsan Hospital, 1035, 
      Dalgubeol-daero, Daegu, Dalseo-gu,, 42601, South Korea.
FAU - Jeon, Jin-Hwa
AU  - Jeon JH
AD  - Cardiovascular Center, Keimyung University Dongsan Hospital, 1035, 
      Dalgubeol-daero, Daegu, Dalseo-gu,, 42601, South Korea.
FAU - Choi, Sang-Woong
AU  - Choi SW
AD  - Cardiovascular Center, Keimyung University Dongsan Hospital, 1035, 
      Dalgubeol-daero, Daegu, Dalseo-gu,, 42601, South Korea.
FAU - Lee, Cheol Hyun
AU  - Lee CH
AUID- ORCID: 0000-0003-4203-1457
AD  - Cardiovascular Center, Keimyung University Dongsan Hospital, 1035, 
      Dalgubeol-daero, Daegu, Dalseo-gu,, 42601, South Korea.
FAU - Kim, In-Cheol
AU  - Kim IC
AUID- ORCID: 0000-0002-5751-2328
AD  - Cardiovascular Center, Keimyung University Dongsan Hospital, 1035, 
      Dalgubeol-daero, Daegu, Dalseo-gu,, 42601, South Korea.
FAU - Cho, Yun-Kyeong
AU  - Cho YK
AUID- ORCID: 0000-0002-0221-0971
AD  - Cardiovascular Center, Keimyung University Dongsan Hospital, 1035, 
      Dalgubeol-daero, Daegu, Dalseo-gu,, 42601, South Korea.
FAU - Yoon, Hyuck-Jun
AU  - Yoon HJ
AUID- ORCID: 0000-0002-0563-7014
AD  - Cardiovascular Center, Keimyung University Dongsan Hospital, 1035, 
      Dalgubeol-daero, Daegu, Dalseo-gu,, 42601, South Korea.
FAU - Kim, Hyungseop
AU  - Kim H
AUID- ORCID: 0000-0001-7056-4221
AD  - Cardiovascular Center, Keimyung University Dongsan Hospital, 1035, 
      Dalgubeol-daero, Daegu, Dalseo-gu,, 42601, South Korea.
FAU - Nam, Chang-Wook
AU  - Nam CW
AUID- ORCID: 0000-0002-3370-5774
AD  - Cardiovascular Center, Keimyung University Dongsan Hospital, 1035, 
      Dalgubeol-daero, Daegu, Dalseo-gu,, 42601, South Korea.
FAU - Hur, Seung-Ho
AU  - Hur SH
AUID- ORCID: 0000-0002-3895-1915
AD  - Cardiovascular Center, Keimyung University Dongsan Hospital, 1035, 
      Dalgubeol-daero, Daegu, Dalseo-gu,, 42601, South Korea.
LA  - eng
GR  - HI17C2594/Korea Health Industry Development Institute/Republic of Korea
PT  - Journal Article
DEP - 20191230
PL  - Netherlands
TA  - J Interv Card Electrophysiol
JT  - Journal of interventional cardiac electrophysiology : an international journal of 
      arrhythmias and pacing
JID - 9708966
SB  - IM
MH  - Atrial Fibrillation/*diagnostic imaging/*surgery
MH  - *Atrial Function, Left
MH  - Catheter Ablation/*methods
MH  - *Echocardiography, Three-Dimensional
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Tomography, X-Ray Computed
PMC - PMC7036070
OTO - NOTNLM
OT  - Atrial fibrillation
OT  - Atrial remodeling
OT  - Catheter ablation
OT  - Left atrium
OT  - Three-dimensional echocardiography
COIS- The authors declare that they have no conflict of interest.
EDAT- 2020/01/01 06:00
MHDA- 2021/01/20 06:00
PMCR- 2019/12/30
CRDT- 2020/01/01 06:00
PHST- 2019/10/05 00:00 [received]
PHST- 2019/12/23 00:00 [accepted]
PHST- 2020/01/01 06:00 [pubmed]
PHST- 2021/01/20 06:00 [medline]
PHST- 2020/01/01 06:00 [entrez]
PHST- 2019/12/30 00:00 [pmc-release]
AID - 10.1007/s10840-019-00696-8 [pii]
AID - 696 [pii]
AID - 10.1007/s10840-019-00696-8 [doi]
PST - ppublish
SO  - J Interv Card Electrophysiol. 2020 Jan;57(1):87-95. doi: 
      10.1007/s10840-019-00696-8. Epub 2019 Dec 30.