PMID- 31890700
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220412
IS  - 2251-6581 (Print)
IS  - 2251-6581 (Electronic)
IS  - 2251-6581 (Linking)
VI  - 18
IP  - 2
DP  - 2019 Dec
TI  - Severe hypoglycemia due to insulin self-injection as a cause of acute ST 
      elevation myocardial infarction.
PG  - 739-742
LID - 10.1007/s40200-019-00431-0 [doi]
AB  - INTRODUCTION: The role of hypoglycemia in cardiovascular disease still needs to 
      be evaluated. Incidental case studies provide direct, but so far limited, 
      evidence for the direct impairment of heart caused by hypoglycemia. We present a 
      case of severe hypoglycemia manifesting with acute ST elevation myocardial 
      infarction (STEMI). CASE PRESENTATION: A 48-year old man committed a suicidal 
      attempt by insulin self-injection. The emerged hypoglycemia was accompanied by 
      ECG changes and positive troponins confirming the diagnosis of STEMI. Urgent 
      coronary angiography was performed, but no acute coronary artery closure/critical 
      stenosis was found. After resolution of hypoglycemia all signs of ischemia 
      diminished. Insulin and C-peptide levels confirmed exogenous hyperinsulinemia, 
      confirming insulin self-injection. Sadly, the patient suffered irreversible brain 
      damage. CONCLUSION: This patient case shows that severe hypoglycemia can 
      precipitate acute STEMI.
CI  - (c) Springer Nature Switzerland AG 2019.
FAU - Benko, Jakub
AU  - Benko J
AD  - Department of Internal Medicine I, Jessenius Faculty of Medicine in Martin, 
      Comenius University in Bratislava, Kollarova 2, 036 59 Martin, Slovakia. GRID: 
      grid.7634.6. ISNI: 0000000109409708
FAU - Bolek, Tomas
AU  - Bolek T
AD  - Department of Internal Medicine I, Jessenius Faculty of Medicine in Martin, 
      Comenius University in Bratislava, Kollarova 2, 036 59 Martin, Slovakia. GRID: 
      grid.7634.6. ISNI: 0000000109409708
FAU - Pridavkova, Dana
AU  - Pridavkova D
AD  - Department of Internal Medicine I, Jessenius Faculty of Medicine in Martin, 
      Comenius University in Bratislava, Kollarova 2, 036 59 Martin, Slovakia. GRID: 
      grid.7634.6. ISNI: 0000000109409708
FAU - Galajda, Peter
AU  - Galajda P
AD  - Department of Internal Medicine I, Jessenius Faculty of Medicine in Martin, 
      Comenius University in Bratislava, Kollarova 2, 036 59 Martin, Slovakia. GRID: 
      grid.7634.6. ISNI: 0000000109409708
FAU - Samos, Matej
AU  - Samos M
AUID- ORCID: 0000-0002-5561-2560
AD  - Department of Internal Medicine I, Jessenius Faculty of Medicine in Martin, 
      Comenius University in Bratislava, Kollarova 2, 036 59 Martin, Slovakia. GRID: 
      grid.7634.6. ISNI: 0000000109409708
FAU - Mokan, Marian
AU  - Mokan M
AD  - Department of Internal Medicine I, Jessenius Faculty of Medicine in Martin, 
      Comenius University in Bratislava, Kollarova 2, 036 59 Martin, Slovakia. GRID: 
      grid.7634.6. ISNI: 0000000109409708
LA  - eng
PT  - Case Reports
DEP - 20190810
PL  - Switzerland
TA  - J Diabetes Metab Disord
JT  - Journal of diabetes and metabolic disorders
JID - 101590741
PMC - PMC6915245
OTO - NOTNLM
OT  - Hypoglycemia
OT  - Insulin self-injection
OT  - STEMI
OT  - Suicide
COIS- Conflict of interestJakub Benko, Tomas Bolek, Dana Pridavkova, Peter Galajda, 
      Matej Samos, and Marian Mokan declare that they have no conflicts of interest 
      that might be relevant to the contents of this manuscript.
EDAT- 2020/01/01 06:00
MHDA- 2020/01/01 06:01
PMCR- 2020/08/10
CRDT- 2020/01/01 06:00
PHST- 2019/05/29 00:00 [received]
PHST- 2019/08/04 00:00 [accepted]
PHST- 2020/01/01 06:00 [entrez]
PHST- 2020/01/01 06:00 [pubmed]
PHST- 2020/01/01 06:01 [medline]
PHST- 2020/08/10 00:00 [pmc-release]
AID - 431 [pii]
AID - 10.1007/s40200-019-00431-0 [doi]
PST - epublish
SO  - J Diabetes Metab Disord. 2019 Aug 10;18(2):739-742. doi: 
      10.1007/s40200-019-00431-0. eCollection 2019 Dec.