PMID- 31892027
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20200106
LR  - 20200106
IS  - 1873-3573 (Electronic)
IS  - 0039-9140 (Linking)
VI  - 209
DP  - 2020 Mar 1
TI  - An analytical strategy based on the combination of ultrasound assisted flat 
      membrane liquid phase microextraction and a smartphone reader for trace 
      determination of malondialdehyde.
PG  - 120618
LID - S0039-9140(19)31251-2 [pii]
LID - 10.1016/j.talanta.2019.120618 [doi]
AB  - In the present work, a new cleanup process entitled ultrasonic assisted flat 
      membrane liquid phase microextraction (UA-FM-LPME) was introduced. The UA-FM-LPME 
      procedure in two phase format was applied for the extraction-preconcentration of 
      malondialdehyde (MDA) as an analyte model from the biological samples after a 
      derivatization reaction. In the designed extraction setup, the simultaneous use 
      of two flat sheet membranes and the application of ultrasonic radiation provided 
      the efficient mass transfer of MDA into the acceptor phase in a short extraction 
      time (2 min). The collected organic phase was then analyzed through 
      Red-Green-Blue (RGB) image analysis and high-performance liquid chromatography 
      coupled with ultraviolet-visible spectroscopy (HPLC-UV/Vis) as detection methods. 
      The key parameters affecting the extraction process were studied and optimized in 
      detail. The effect of the sugaring out on the partition of MDA into the 
      extraction phase was examined for the first time. Under optimal conditions, 
      linearity was observed in the concentration range of 8-1000 ng mL(-1) for HPLC, 
      and 10-1000 ng mL(-1) for RGB analysis, with the coefficient of determination 
      (R(2)) values higher than 0.9973. The introduced method also offered satisfactory 
      relative standard deviations (RSDs) less than 4.0%. In order to examine the 
      reliability of the technique in complicated matrices, three different biological 
      samples (urine, saliva and blood plasma) were analyzed and the acceptable results 
      in terms of relative recoveries (89.7-102.4%) were obtained. The designed setup 
      in combination with RGB analysis will provide a low-cost alternative technique 
      for rapid determination of MDA in clinical diagnosis or biochemical analysis 
      without the need to complex, time consuming and expensive analytical instruments.
CI  - Copyright (c) 2019 Elsevier B.V. All rights reserved.
FAU - Fashi, Armin
AU  - Fashi A
AD  - Environmental Science Research Laboratory, Department of Environmental Science, 
      Faculty of Science, University of Zanjan, Postal Code 45371-38791, Zanjan, Iran. 
      Electronic address: arminfashi@znu.ac.ir.
FAU - Cheraghi, Mahdi
AU  - Cheraghi M
AD  - Environmental Science Research Laboratory, Department of Environmental Science, 
      Faculty of Science, University of Zanjan, Postal Code 45371-38791, Zanjan, Iran.
FAU - Badiee, Hamid
AU  - Badiee H
AD  - Environmental Science Research Laboratory, Department of Environmental Science, 
      Faculty of Science, University of Zanjan, Postal Code 45371-38791, Zanjan, Iran; 
      Department of Chemistry, Faculty of Science, University of Guilan, University 
      Campus 2, Rasht, Iran.
FAU - Zamani, Abbasali
AU  - Zamani A
AD  - Environmental Science Research Laboratory, Department of Environmental Science, 
      Faculty of Science, University of Zanjan, Postal Code 45371-38791, Zanjan, Iran. 
      Electronic address: Zamani@znu.ac.ir.
LA  - eng
PT  - Journal Article
DEP - 20191204
PL  - Netherlands
TA  - Talanta
JT  - Talanta
JID - 2984816R
SB  - IM
OTO - NOTNLM
OT  - Biological samples
OT  - Derivatization
OT  - Membrane extraction
OT  - Preconcentration
OT  - RGB analysis
OT  - Sugaring out
EDAT- 2020/01/02 06:00
MHDA- 2020/01/02 06:01
CRDT- 2020/01/02 06:00
PHST- 2019/11/05 00:00 [received]
PHST- 2019/12/02 00:00 [revised]
PHST- 2019/12/03 00:00 [accepted]
PHST- 2020/01/02 06:00 [entrez]
PHST- 2020/01/02 06:00 [pubmed]
PHST- 2020/01/02 06:01 [medline]
AID - S0039-9140(19)31251-2 [pii]
AID - 10.1016/j.talanta.2019.120618 [doi]
PST - ppublish
SO  - Talanta. 2020 Mar 1;209:120618. doi: 10.1016/j.talanta.2019.120618. Epub 2019 Dec 
      4.