PMID- 31893001
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 1920-8642 (Print)
IS  - 1920-8642 (Linking)
VI  - 11
IP  - 1
DP  - 2020
TI  - The first two cases of transcatheter mitral valve repair with ARTO system in 
      Asia.
PG  - 33-36
LID - 10.5847/wjem.j.1920-8642.2020.01.005 [doi]
AB  - BACKGROUND: MAVERIC (Mitral Valve Repair Clinical Trial) validates the safety and 
      efficacy of the ARTO system. We here report the first two successful cases of 
      utilizing the ARTO system in patients with symptomatic heart failure (HF) with 
      functional mitral regurgitation (FMR) in Asia. METHODS: Two patients, aged 70 and 
      63, had severe HF with FMR. Transesophageal echocardiography confirmed that the 
      left ventricular ejection fractions were less than 50% with severe mitral 
      regurgitation (MR) in both patients. Optimizing drug treatment could not mitigate 
      their symptoms. Therefore, we used the ARTO system to repair the mitral valve for 
      these patients on March 5 and 6, 2019, respectively. RESULTS: Mitral valve 
      repairs using the ARTO system were successfully performed under general 
      anaesthesia for these two patients. MR was decreased immediately after the 
      procedures in both patients. The 30-day and 3-month transthoracic 
      echocardiography (TTE) revealed a moderate to severe MR in both patients, and the 
      New York Heart Association (NYHA) scales were also partially improved. 
      CONCLUSION: The first two cases in Asia indicate that the ARTO system is feasible 
      for patients with heart failure with FMR, and the patient selection appears to be 
      crucial.
CI  - Copyright: (c) 2020 World Journal of Emergency Medicine.
FAU - Ren, Kai-da
AU  - Ren KD
AD  - Cardiovascular Department, the Second Affiliated Hospital, Zhejiang University 
      School of Medicine, Hangzhou 310009, China.
FAU - Pu, Zhao-Xia
AU  - Pu ZX
AD  - Cardiovascular Department, the Second Affiliated Hospital, Zhejiang University 
      School of Medicine, Hangzhou 310009, China.
FAU - Yu, Lei
AU  - Yu L
AD  - Cardiovascular Department, the Second Affiliated Hospital, Zhejiang University 
      School of Medicine, Hangzhou 310009, China.
FAU - Gao, Feng
AU  - Gao F
AD  - Cardiovascular Department, the Second Affiliated Hospital, Zhejiang University 
      School of Medicine, Hangzhou 310009, China.
FAU - Wang, Li-Han
AU  - Wang LH
AD  - Cardiovascular Department, the Second Affiliated Hospital, Zhejiang University 
      School of Medicine, Hangzhou 310009, China.
FAU - Ng, Stella
AU  - Ng S
AD  - Cardiovascular Department, the Second Affiliated Hospital, Zhejiang University 
      School of Medicine, Hangzhou 310009, China.
FAU - Jiang, Ju-Bo
AU  - Jiang JB
AD  - Cardiovascular Department, the Second Affiliated Hospital, Zhejiang University 
      School of Medicine, Hangzhou 310009, China.
FAU - Li, Hua-Jun
AU  - Li HJ
AD  - Cardiovascular Department, the Second Affiliated Hospital, Zhejiang University 
      School of Medicine, Hangzhou 310009, China.
FAU - Xu, Yong
AU  - Xu Y
AD  - Cardiovascular Department, the Second Affiliated Hospital, Zhejiang University 
      School of Medicine, Hangzhou 310009, China.
FAU - He, Wei
AU  - He W
AD  - Cardiovascular Department, the Second Affiliated Hospital, Zhejiang University 
      School of Medicine, Hangzhou 310009, China.
FAU - Yan, Min
AU  - Yan M
AD  - Cardiovascular Department, the Second Affiliated Hospital, Zhejiang University 
      School of Medicine, Hangzhou 310009, China.
FAU - Liu, Xian-Bao
AU  - Liu XB
AD  - Cardiovascular Department, the Second Affiliated Hospital, Zhejiang University 
      School of Medicine, Hangzhou 310009, China.
FAU - Wang, Jian-An
AU  - Wang JA
AD  - Cardiovascular Department, the Second Affiliated Hospital, Zhejiang University 
      School of Medicine, Hangzhou 310009, China.
LA  - eng
PT  - Journal Article
PL  - China
TA  - World J Emerg Med
JT  - World journal of emergency medicine
JID - 101549691
PMC - PMC6885581
OTO - NOTNLM
OT  - ARTO system
OT  - Mitral regurgitation
OT  - Mitral valve repair
COIS- Conflicts of interest: The authors declare that they have no competing interests. 
      The funders had no role in the design, conduct, analysis, or interpretation of 
      data or in writing the manuscript.
EDAT- 2020/01/02 06:00
MHDA- 2020/01/02 06:01
PMCR- 2020/01/01
CRDT- 2020/01/02 06:00
PHST- 2020/01/02 06:00 [entrez]
PHST- 2020/01/02 06:00 [pubmed]
PHST- 2020/01/02 06:01 [medline]
PHST- 2020/01/01 00:00 [pmc-release]
AID - WJEM-11-33 [pii]
AID - 10.5847/wjem.j.1920-8642.2020.01.005 [doi]
PST - ppublish
SO  - World J Emerg Med. 2020;11(1):33-36. doi: 10.5847/wjem.j.1920-8642.2020.01.005.