PMID- 31900638 OWN - NLM STAT- MEDLINE DCOM- 20201230 LR - 20201230 IS - 1435-702X (Electronic) IS - 0721-832X (Linking) VI - 258 IP - 3 DP - 2020 Mar TI - Impact of optical coherence tomography angiography on the non-invasive diagnosis of neovascular age-related macular degeneration. PG - 537-541 LID - 10.1007/s00417-019-04581-y [doi] AB - PURPOSE: To investigate the changes in imaging tool practice for the diagnosis of neovascular age-related macular degeneration (nAMD). METHODS: Retrospective analysis of consecutive patients diagnosed with nAMD in a tertiary care center, over a 6-month period in 2014, 2016, and 2018. Patient demographics were compared. Imaging modalities used in 2014 were fundus photography, fluorescein angiography (FA), and structural spectral-domain optical coherence tomography (SD-OCT), while OCT-angiography (OCT-A) was available from 2015. Imaging tools used in our practice were compared in the 3 cohorts. RESULTS: The 3 cohorts included 163, 99, and 167 patients, respectively. There was no difference in age or gender (mean age 81.7 years). OCT-A images were analyzable in 60.5% and 89.7% of patients respectively in 2016 and in 2018. In the 3 cohorts, all patients were imaged with fundus photography and structural OCT. FA was performed in 70.2, 28.8, and 22.1% of patients, respectively. CONCLUSION: This study showed a shift in practice of imaging tools used for the diagnosis of nAMD, non-invasive tools being increasingly used as the first-line imaging, and FA as the second-line imaging. FAU - Giocanti-Auregan, Audrey AU - Giocanti-Auregan A AD - Department of Ophthalmology, Hopital Avicenne, AP-HP and University Paris 13, Bobigny, France. FAU - Dubois, Lise AU - Dubois L AD - Ophthalmology Center for Imaging and Laser, Paris, France. FAU - Dourmad, Pauline AU - Dourmad P AD - Ophthalmology Center for Imaging and Laser, Paris, France. FAU - Cohen, Salomon Y AU - Cohen SY AUID- ORCID: 0000-0003-1181-4379 AD - Ophthalmology Center for Imaging and Laser, Paris, France. sycsyc75@gmail.com. AD - Department of Ophthalmology, University of Paris Est, Creteil, France. sycsyc75@gmail.com. AD - Centre Ophtalmologique d'Imagerie et de Laser, 11 Rue Antoine Bourdelle, 75015, Paris, France. sycsyc75@gmail.com. LA - eng PT - Journal Article DEP - 20200103 PL - Germany TA - Graefes Arch Clin Exp Ophthalmol JT - Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie JID - 8205248 SB - IM MH - Aged MH - Aged, 80 and over MH - Female MH - Fluorescein Angiography/*methods MH - Follow-Up Studies MH - Fundus Oculi MH - Humans MH - Macula Lutea/*pathology MH - Male MH - Reproducibility of Results MH - Retrospective Studies MH - Time Factors MH - Tomography, Optical Coherence/*methods MH - *Visual Acuity MH - Wet Macular Degeneration/*diagnosis OTO - NOTNLM OT - Age-related macular degeneration OT - Fluorescein angiography OT - OCT-angiography EDAT- 2020/01/05 06:00 MHDA- 2020/12/31 06:00 CRDT- 2020/01/05 06:00 PHST- 2019/10/04 00:00 [received] PHST- 2019/12/19 00:00 [accepted] PHST- 2019/12/18 00:00 [revised] PHST- 2020/01/05 06:00 [pubmed] PHST- 2020/12/31 06:00 [medline] PHST- 2020/01/05 06:00 [entrez] AID - 10.1007/s00417-019-04581-y [pii] AID - 10.1007/s00417-019-04581-y [doi] PST - ppublish SO - Graefes Arch Clin Exp Ophthalmol. 2020 Mar;258(3):537-541. doi: 10.1007/s00417-019-04581-y. Epub 2020 Jan 3.